Buscar en:

Empiece una nueva busqueda
Add/Remove Filters (2 filters currently applied)

Resultados 1-50 de 132.
 |  Relevancia

 

Resultados por ítem:
DerechosPreviewFecha Public.TítuloAutor(es)Tipo
1closedAccessaccesoRestringido.pdf.jpg2018Neurotoxic Ca2+ signaling induced by amyloid–β oligomers in aged hippocampal neurons in vitroNúñez, Lucía CSIC ORCID; Calvo-Rodríguez, María CSIC ORCID; García-Durillo, Mónica CSIC; Villalobos, Carlos CSIC ORCIDcapítulo de libro
2closedAccessaccesoRestringido.pdf.jpg2012Proteostasis of tau. Tau overexpression results in its secretion via membrane vesiclesSimón, Diana CSIC ORCID; García-García, Esther CSIC; Royo, Félix; Falcón-Pérez, Juan M. CSIC ORCID; Ávila, Jesús CSIC ORCID artículo
3openAccessExpert Opinion on Therapeutic Patents_palomo_2016.pdf.jpg21-nov-2016Glycogen synthase kinase 3 (GSK-3) inhibitors: a patent update (2014-2015)Palomo, Valle CSIC ORCID ; Martínez Gil, Ana CSIC ORCID artículo
4closedAccessaccesoRestringido.pdf.jpg28-may-2019Identification of Alzheimer's Disease Autoantibodies and Their Target Biomarkers by Phage MicroarraysSan Segundo-Acosta, Pablo; Montero-Calle, Ana; Fuentes, Manuel CSIC ORCID ; Rábano, Alberto; Villalba, Mayte; Barderas, Rodrigo CSIC ORCIDartículo
5closedAccessaccesoRestringido.pdf.jpg2017Recent Developments on Multi-Target-Directed Tacrines for Alzheimer's Disease. I. The PyranotacrinesRomero Jódar, Alejandro CSIC ORCID; Marco-Contelles, José CSIC ORCIDartículo
6closedAccessaccesoRestringido.pdf.jpg2019Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer's disease therapyMalek, R.; Maj, M.; Wnorowski, A.; Józwiak, K.; Martin, Helene; Iriepa, Isabel; Moraleda, I.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, L.artículo
7openAccesscerebrospinalfluid.pdf.jpg2017Kidins220 correlates with tau in Alzheimer's disease brain and cerebrospinal fluidGamir-Morralla, Andrea CSIC; Belbin, Olivia CSIC; Fortea, Juan; Alcolea, Daniel; Ferrer, Isidro; Lleó, Alberto; Iglesias, Teresa CSIC ORCIDartículo
8openAccessMOLN_Boya_2015.pdf.jpg28-oct-2015Altered blood gene expression of tumor-related genes (PRKCB, BECN1 and CDKN2A) in Alzheimer’s diseaseAntonell, Anna; Sanfeliu, Coral CSIC ORCID; Boya, Patricia CSIC ORCID ; Molinuevo, José Luisartículo
9openAccessmolecules-24-01307.pdf.jpg3-abr-2019Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer’s DiseaseKohelová, Eliška; Peřinová, Rozálie; Maafi, Negar; Korábečný, Jan; Hulcová, Daniela; Maříková, Jana; Kučera, Tomáš; Martínez-González, Loreto CSIC ORCID ; Hrabinová, Martina; Vorčáková, Katarina; Nováková, Lucie; De Simone, Angela; Havelek, Radim; Cahlíková, Lucieartículo
10closedAccessaccesoRestringido.pdf.jpg2013Synthesis, pharmacological assessment, and molecular modeling of 6-chloro-pyridonepezils: New dual AChE inhibitors as potential drugs for the treatment of Alzheimer's diseaseSamadi, Abdelouahid CSIC ORCID; Fuente Revenga, Mario de la CSIC ORCID; Pérez, Concepción CSIC ORCID; Iriepa, Isabel; Moraleda, Ignacio; Rodríguez-Franco, María Isabel CSIC ORCID ; Marco-Contelles, José CSIC ORCIDartículo
11closedAccessaccesoRestringido.pdf.jpg2013GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivoLlorens-Martín, María CSIC ORCID ; Fuster-Matanzo, Almudena CSIC; Teixeira, Catia M.; Jurado-Arjona, Jerónimo CSIC; Ulloa, Fausto; DeFelipe, Javier CSIC ORCID ; Rábano, Alberto; Hernández Pérez, Félix CSIC ORCID; Soriano, Eduardo; Ávila, Jesús CSIC ORCID artículo
12openAccess15-oct-2018Tau Tubulin Kinase 1 (TTBK1), a new player in the fight against neurodegenerative diseasesNozal, Vanesa CSIC ORCID; Martínez Gil, Ana CSIC ORCID artículo
13closedAccessaccesoRestringido.pdf.jpg2011Epigenetic Control of Somatostatin and Cortistatin Expression by Beta Amyloid PeptideRubio, Alicia; Sánchez-Mut, José V.; García, Esther; Velasquez, Zahady D.; Oliver de la Cruz, Jorge CSIC; Esteller, Manel; Ávila, Jesús CSIC ORCID artículo
14closedAccess8-jul-2010Simvastatin overcomes the resistance to serum withdrawal-induced apoptosis of lymphocytes from Alzheimer´s disease patientsBartolomé Robledo, Fernando CSIC ORCID; Muñoz, Úrsula; Esteras, Noemí CSIC ORCID; Alquézar, Carolina CSIC ORCID; Collado, Andrea; Bermejo-Pareja, Félix; Martín-Requero, Ángeles CSIC ORCID artículo
15openAccessCNS postprint 2018.pdf.jpg7-may-2018Activation of the cannabinoid type 2 receptor by a novel indazole derivative normalizes the survival pattern of lymphoblasts from patients with late-onset alzheimer’s diseaseDel Cerro, Patricia; Alquézar, Carolina CSIC ORCID; Bartolomé Robledo, Fernando CSIC ORCID; González-Naranjo, Pedro CSIC ORCID; Pérez, Concepción CSIC ORCID; Carro, Eva CSIC ORCID; Páez, Juan A. CSIC ORCID; Campillo, Nuria E. CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID artículo
16closedAccess2011N-Acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer’s diseaseGonzález Muñoz, Gema C.; Arce, Mariana P. CSIC; López, Beatriz; López, Beatriz; Romero Jódar, Alejandro CSIC ORCID; del Barrio, Laura; Martín de Saavedra, María Dolores; Egea, Javier; León, Rafael CSIC ORCID ; Villarroya, Mercedes; López, Manuela G.; García, Antonio G.; Conde, Santiago CSIC; Rodríguez-Franco, María Isabel CSIC ORCID artículo
17openAccess2016Armañanzas et al_IEEEJournal of biomedical and Health informatics.pdf.jpg2017Voxel-Based Diagnosis of Alzheimer's Disease Using Classifier EnsemblesArmañanzas, Rubén; Iglesias, Martina; Morales, Dinora A; Alonso-Nanclares, Lidia CSIC ORCID CVN artículo
18openAccessÁvilaJ_LithiumasaTreatmentforAlzheimer’s.pdf.jpg29-mar-2019Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology PerspectiveHampel, Harald; Lista, Simone; Mango, Dalila; Nisticó, Robert; Perry, George; Ávila, Jesús CSIC ORCID ; Hernández, Félix; Geerts, Hugo; Vergallo, Andreaartículo de revisión
19openAccessÁvilaJ_The GABAergicSeptohippocampal.pdf.jpg15-sep-2016The GABAergic septohippocampal connection is impaired in a mouse model of tauopathySoler, Helena; Dorca-Arévalo, Jonatan; Gonzalez, Marta; Rubio, Sara E.; Ávila, Jesús CSIC ORCID ; Soriano, Eduardo; Pascual. Martaartículo
20closedAccessaccesoRestringido.pdf.jpg2017Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amineDe Deurwaerdère, Phillippe; Binda, Claudia; Corne, R.; Leone, C.; Valeri, A.; Valoti, M.; Ramsay, R. R.; Fall, Yagamare; Marco-Contelles, José CSIC ORCIDartículo
21openAccessÁvilaJ_FragmentationoftheGolgi.pdf.jpg23-jul-2018Fragmentation of the Golgi Apparatus in Neuroblastoma Cells Is Associated with Tau-Induced Ring-Shaped Microtubule BundlesRodríguez-Cruz, Fanny; Torres-Cruz, Francisco M.; Monroy-Ramírez, Hugo C.; Escobar-Herrera, Jaime; Basurto-Islas, Gustavo; Ávila, Jesús CSIC ORCID ; García-Sierra, Franciscoartículo
22closedAccess2016Brain local and regional neuroglial alterations in Alzheimer´s disease Cell types, responses and implicationsToledano-Díaz, A. CSIC ORCID ; Álvarez, M. Isabel; Toledano-Díaz, A. CSIC ORCID ; Merino, José Joaquín; Rodríguez, J. J.artículo de revisión
23closedAccessaccesoRestringido.pdf.jpg2012Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic miceSilveyra, María Ximena CSIC ORCID; García-Ayllón, María-Salud CSIC ORCID; Gómez de Barreda, Elena CSIC; Small, David H.; Martínez, Salvador CSIC ORCID; Ávila, Jesús CSIC ORCID ; Sáez-Valero, Javier CSIC ORCIDartículo
24openAccessJEIMC_Sciú_2018.pdf.jpg1-ene-2019Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3Sciú, María Lourdes; Sebastián-Pérez, Víctor; Martínez-González, Loreto CSIC ORCID ; Benítez, Rocio; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Moyano, Elizabeth Lauraartículo
25openAccesscerebrospinal_fluid_Sogord.pdf.jpg29-sep-2016Cerebrospinal fluid Presenilin-1 increases at asymptomatic stage in genetically determined Alzheimer’s diseaseSogorb-Esteve, Aitana CSIC; García-Ayllón, María-Salud CSIC ORCID; Fortea, Juan; Sánchez-Valle, Raquel; Lleó, Alberto; Molinuevo, José Luis; Sáez-Valero, Javier CSIC ORCIDartículo
26openAccessÁvilaJ_UntoldNewBeginnings.pdf.jpg2018Untold New Beginnings: Adult Hippocampal Neurogenesis and Alzheimer's DiseaseTeixeira, Catia M.; Pallas-Bazarra, Noemí CSIC ORCID; Bolós, Marta CSIC ORCID; Terreros-Roncal, Julia; Ávila, Jesús CSIC ORCID ; Llorens-Martín, María CSIC ORCID artículo de revisión
27openAccessActa Cryst. (2018). C74, 513–522.pdf.jpg2018The structures of 1,4-diaryl-5-trifluoromethyl-1H-1,2,3-triazoles related to J147, a drug for treating Alzheimer's diseaseFarrán, M. Ángeles; Bonet, Maria Angels; Claramunt, Rosa M.; Torralba, M. Carmen; Alkorta, Ibon CSIC ORCID ; Elguero, José CSIC ORCIDartículo
28openAccessEsteras_Current_Alzh_Res_2012_9_3.pdf.jpgmar-2012Altered calmodulin degradation and signaling in non-neuronal cells from Alzheimer’s disease patientsEsteras, Noemí CSIC ORCID; Muñoz, Úrsula; Alquézar, Carolina CSIC ORCID; Bartolomé Robledo, Fernando CSIC ORCID; Bermejo-Pareja, Félix; Martín-Requero, Ángeles CSIC ORCID artículo
29openAccessCarrascoL_InfectionOfFungi.pdf.jpg24-may-2018Infection of fungi and bacteria in brain tissue from elderly persons and patients with Alzheimer's diseaseAlonso, Ruth CSIC ORCID; Pisa, Diana CSIC; Fernández-Fernández, Ana M.; Carrasco, Luísartículo
30openAccess2018 PNAS 115-11625.pdf.jpg6-nov-2018Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathologyDíaz-Moreno, María; Armenteros, Tomás CSIC; Gradari, Simona CSIC; Hortigüela, Rafael CSIC ORCID; García-Corzo, Laura CSIC ORCID CVN; Fontán-Lozano, Ángela CSIC ORCID; Trejo, José L. CSIC ORCID; Mira, Helena CSIC ORCID artículo
31openAccessAvilaJ_GSK-3MouseModels.pdf.jpg16-nov-2011GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration.Gómez-Sintes, Raquel CSIC ORCID ; Hernández Pérez, Félix CSIC ORCID; Lucas, José Javier CSIC ORCID; Ávila, Jesús CSIC ORCID artículo
32openAccess1 Benzo d thiazol 2 yl 3 phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders.pdf.jpg14-mar-20181-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disordersBenek, O.; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Musilek, Kamilartículo
33closedAccessaccesoRestringido.pdf.jpg2017Synthesis and biological assessment of racemic benzochromenopyrimidinetriones as promising agents for Alzheimer's disease therapyDgachi, Youssef; Martin, Hélène; Bonet, Alexandre; Chioua, Mourad CSIC ORCID ; Iriepa, Isabel; Moraleda, Ignacio; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassaneartículo
34openAccessrathippocampal.pdf.jpg2017Aging and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca2+ responses, and neuron cell death in cultured rat hippocampal neuronsCalvo-Rodríguez, María CSIC ORCID; Fuente, Carmen de la; García-Durillo, Mónica CSIC; García-Rodríguez, Carmen CSIC ORCID; Villalobos, Carlos CSIC ORCID; Núñez, Lucía CSIC ORCIDartículo
35openAccessSastreI_MAPT1HaplotypeIsAssocieatedWithLate-Onset.pdf.jpg2015MAPT H1 haplotype is associated with late-onset Alzheimer's disease risk in APOE ε 4 noncarriers: Results from the dementia genetics Spanish consortiumPastor, Pau; Bullido, María Jesús CSIC ORCID; Sastre, Isabel CSIC ORCID; Sánchez-Juan, Pascualartículo
36openAccessJesus_Avila_GSK3.pdf.jpg2012GSK3 and tau: Two convergence points in Alzheimer's diseaseHernández Pérez, Félix CSIC ORCID; Lucas, José Javier CSIC ORCID; Ávila, Jesús CSIC ORCID artículo
37openAccessAldudoJ_HerpesSimplexVirusType2Infection.pdf.jpg18-jun-2015Herpes simplex virus type 2 infection induces AD-like neurodegeneration markers in human neuroblastoma cellsKristen, Henrike; Santana, Soraya; Sastre, Isabel CSIC ORCID; Recuero, María CSIC; Bullido, María Jesús CSIC ORCID; Aldudo, Jesús CSIC ORCIDartículo
38openAccessnutrients-11-01764-v2.pdf.jpg31-jul-2019Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer’s Disease PatientsCosín-Tomás, Marta CSIC ORCID; Senserrich, Júlia CSIC ORCID; Arumí-Planas, Marta CSIC ORCID; Alquézar, Carolina CSIC ORCID; Pallàs, Mercè; Martín-Requero, Ángeles CSIC ORCID ; Suñol, Cristina CSIC ORCID ; Kaliman, Perla CSIC; Sanfeliu, Coral CSIC ORCIDartículo
39closedAccessaccesoRestringido.pdf.jpg2016Aging enables Ca2+ overload and apoptosis induced by amyloid-β oligomers in rat hippocampal neurons: Neuroprotection by non-steroidal anti-inflammatory drugs and r-flurbiprofen in aging neuronsCalvo-Rodríguez, María CSIC ORCID; García-Durillo, Mónica CSIC; Villalobos, Carlos CSIC ORCID; Núñez, Lucía CSIC ORCIDartículo
40openAccessÁvila_GSK3bOverexpressionInduces.pdf.jpg23-jun-2010GSK3β overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrusSirerol-Piquer, María Salomé CSIC; Gómez-Ramos, Pilar; Hernández, Félix; Pérez, Mar CSIC ORCID; Morán, María A.; Fuster-Matanzo, Almudena CSIC; Lucas, José Javier CSIC ORCID; Ávila, Jesús CSIC ORCID ; García-Verdugo, José Manuelartículo
41openAccessjournal.pcbi.1000997.pdf.jpg2010Vulnerabilities in the tau network and the role of ultrasensitive points in Ttu pathophysiologyYuraszeck, Theresa M.; Neveu, Pierre; Rodríguez Fernández, María CSIC ORCID; Robinson, Anne; Kosik, Kenneth S.; Doyle, Francis J.artículo
42openAccessClarkson_et_al-2019-Acta_Crystallographica_Section_C.pdf.jpg2019The structure of the anti-aging agent J147 used for treating Alzheimer’s diseaseClarkson, G. D.; Farrán, M. Ángeles; Claramunt, Rosa M.; Alkorta, Ibon CSIC ORCID ; Elguero, José CSIC ORCIDartículo
43closedAccessrestringido.pdf.jpgsep-2012Altered cell cycle-related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer´s disease [amyloid precursor protein/presenilin 1 (PS1)]Esteras, Noemí CSIC ORCID; Bartolomé Robledo, Fernando CSIC ORCID; Alquézar, Carolina CSIC ORCID; Antequera, Desiree CSIC; Muñoz, Úrsula; Carro, Eva CSIC ORCID; Martín-Requero, Ángeles CSIC ORCID artículo
44openAccessBullido MJ Genetic Variation.pdf.jpg2011Genetic variation in the tau kinases pathway may modify the risk and age at onset of alzheimer's diseaseVázquez-Higuera, José Luis; Valdivieso Amate, Fernando; Bullido, María Jesús CSIC ORCID; Combarros, Onofreartículo
45openAccessÁvilaJ_CommentaryGenome-WideAssociation.pdf.jpg31-ene-2017Commentary: Genome-wide association study identifies 74 loci associated with educational attainmentHernández, Félix; Ávila, Jesús CSIC ORCID artículo
46openAccess13148_2015_Article_142.pdf.jpg8-oct-2015Concomitant histone deacetylase and phosphodiesterase 5 inhibition synergistically prevents the disruption in synaptic plasticity and it reverses cognitive impairment in a mouse model of Alzheimer’s diseaseCuadrado-Tejedor, M.; Mederos, Sara CSIC ORCID; Perea, Gertrudis CSIC ORCID; García-Osta, A.artículo
47closedAccessrestringido.pdf.jpg29-abr-20191-Aryl-3-(4-methoxybenzyl)ureas as potentially irreversible glycogen synthase kinase 3 inhibitors: Synthesis and biological evaluationVenter, Jana; Pérez, Concepción CSIC ORCID; van Otterlo, Willem A. L.; Martínez Gil, Ana CSIC ORCID ; Blackie, Margaret A.L.artículo
48openAccess27-Hydroxycholesterol Induces Aberrant ......-1.pdf.jpg201927-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal NeuronsMerino-Serrais, Paula CSIC ORCID ; Loera-Valencia, Raúl; Rodríguez-Rodríguez, Pilar; Parrado-Fernández, Cristina; Ismail, M.A.; Maioli, Silvia; Matutes, Estella; Jiménez-Mateos, Eva María; Björkhem, I.; DeFelipe, Javier CSIC ORCID ; Cedazo-Mínguez, Ángelartículo
49closedAccessaccesoRestringido.pdf.jpg2013Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer's diseaseRomero Jódar, Alejandro CSIC ORCID; Cacabelos, Ramón; Oset-Gasque, María Jesús; Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCIDartículo
50openAccessWandosell F Role of PrPC.pdf.jpg26-jun-2014Role of PrPC Expression in Tau Protein Levels and Phosphorylation in Alzheimer¿s Disease EvolutionVergara, Cristina; Ordóñez-Gutiérrez, Lara CSIC ORCID; Wandosell, Francisco CSIC ORCID ; Ferrer, I. M; Río, José Antonio del; Gavín, Rosalinalibro
Resultados 1-50 de 132.