Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/228682
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Metabolome-based clustering after moderate wine consumption |
Autor: | Esteban-Fernández, Adelaida CSIC; Ibáñez, Clara CSIC; Simó, Carolina CSIC ORCID ; Bartolomé, Begoña CSIC ORCID ; Moreno-Arribas, M. Victoria CSIC ORCID | Palabras clave: | Polyphenols Wine Urinary metabolome Metabotypes clustering |
Fecha de publicación: | 2020 | Editor: | International Viticulture and Enology Society | Citación: | OENO One 54(3): 455-467 (2020) | Resumen: | Grouping individuals according to their metabolic capacities (metabotyping) has caused a shift from individualised to grouped treatments for the optimisation of nutritional interventions. Several studies have reported a stratification of patients into metabolic clusters after the intake of certain foods, of which polyphenols seem to be mostly associated with metabotypes. Despite this, there is a lack of metabotyping studies regarding wine consumption. In this context, the human urinary metabolome of healthy volunteers (n=41) was explored by means of a non-targeted metabolomic approach after an intervention with red wine (250 mL/day, 28 days). Three clusters of volunteers based on their relative production of phenolic metabolites were perceived , and the compounds responsible for this clustering were identified. To our knowledge, this is the first time that different urinary metabotypes have been described in healthy volunteers after moderate red wine consumption. Our findings suggest that stratification of individuals in clinical trials according to their metabotype is necessary to fully understand the health effects of wine polyphenols. | Versión del editor: | https://doi.org/10.20870/oeno-one.2020.54.3.2983 | URI: | http://hdl.handle.net/10261/228682 | DOI: | 10.20870/oeno-one.2020.54.3.2983 | ISSN: | 2494-1271 |
Aparece en las colecciones: | (CIAL) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
metaboloco.pdf | 1,49 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
8
checked on 24-abr-2024
WEB OF SCIENCETM
Citations
6
checked on 22-feb-2024
Page view(s)
173
checked on 27-abr-2024
Download(s)
171
checked on 27-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.