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| | Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| 1 | closedAccess |  | 2013 | Metabolomics in Alzheimer's disease research | Ibáñez, Clara CSIC; Simó, Carolina CSIC ORCID ; Cifuentes, Alejandro CSIC ORCID | artículo |
| 2 | closedAccess |  | 2015 | Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease | Ramos-Rodriguez, Juan Jose; Jiménez-Palomares, Margarita CSIC ORCID; Lechuga-Sancho, Alfonso María; Cózar-Castellano, Irene CSIC ORCID CVN; García-Alloza, Mónica | artículo |
| 3 | openAccess |  | 1-sep-2019 | Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells | Fanaee-Danesh, Elham; Gali, Chaitanya Chakravarthi; Tadic, Jelena; Zandl-Lang, Martina; Kober, Alexandra Carmen; Roca-Agujetas, Vicente CSIC ORCID; Dios, Cristina de CSIC ORCID; Tam-Amersdorfer, Carmen; Stracke, Anika; Albrecher, Nicole Maria; Manavalan, Anil Paul Chirackal; Reiter, Marielies; Sun, Yidan; Colell Riera, Anna CSIC ORCID; Madeo, Frank; Malle, Ernst; Panzenboeck, Ute | artículo |
| 4 | closedAccess |  | 2017 | Melatonin as a versatile molecule to design novel multitarget hybrids against neurodegeneration | Ramos, E.; Egea, Javier; Rios, C. de los; Marco-Contelles, José CSIC ORCID; Romero, A. | artículo |
| 5 | closedAccess |  | 2013 | The multifactorial nature of Alzheimer's disease for developing potential therapeutics | Carreiras, M. Carmo; Mendes, Eduardo; Perry, M. Jesús; Francisco, Ana Paula; Marco-Contelles, José CSIC ORCID | artículo |
| 6 | closedAccess |  | 2010 | Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome | Rueda, Noemí; Llorens-Martín, María CSIC ORCID ; Flórez, Jesús; Valdizán, Elsa M. CSIC ORCID; Banerjee, Pradeep; Trejo, José L. CSIC ORCID; Martínez-Cué, Carmen | artículo |
| 7 | openAccess |  | 2011 | Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress | Gallego‑Sandín, Sonia; Alonso, María Teresa; García-Sancho, Javier CSIC ORCID | artículo |
| 8 | openAccess |  | 2017 | Enzymatic and solid-phase synthesis of new donepezil-based L- and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia | Monjas, Leticia CSIC ORCID; Arce, Mariana P. CSIC; León, Rafael CSIC ORCID ; Egea, Javier; Pérez, Concepción CSIC ORCID; Villarroya, Mercedes; López, Manuela G.; Gil, Carmen CSIC ORCID ; Conde, Santiago CSIC; Rodríguez-Franco, María Isabel CSIC ORCID | artículo |
| 9 | closedAccess |  | dic-2015 | A truncating mutation in Alzheimer's disease inactivates neuroligin-1 synaptic function | Tristán Clavijo, E. CSIC; Camacho García, R. J. CSIC; Robles Lanuza, Estefanía CSIC; Ruiz, Agustín; van der Zee, Julie; van Broeckhoven, Christine; Hernández, Isabel; Martínez Mir, Amalia CSIC ORCID; Scholl, Francisco G. | artículo |
| 10 | closedAccess |  | 2019 | Physical Exercise During Pregnancy Prevents Cognitive Impairment Induced by Amyloid-ß in Adult Offspring Rats | Peres Klein, Caroline; Bender Hoppe, Juliana; Brum Saccomori, André; Gindri dos Santos, Bernardo; Sagini, João Pedro; Scortegagna Crestani, Mariana; Maciel August, Pauline; Mateus Hözer, Régis; Grings, Mateus; Parmeggiani, Belisa; Leipnitz, Guilhian; Navas, Plácido CSIC ORCID; Gazzana Salbego, Christianne; Matté, Cristiane | artículo |
| 11 | closedAccess |  | 2019 | Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents | Silva, D.; Mendes, Eduarda; Summers, E. J.; Neca, A.; Jacinto, A. C.; Reis, T.; Agostinho, Paula; Bolea, I.; Jimeno, M. Luisa CSIC ORCID; Mateus, M.L.; Oliveira-Campos, A.M.F.; Unzeta, M.; Marco-Contelles, José CSIC ORCID; Majekova, M.; Ramsay, R. R.; Carreiras, M. Carmo | artículo |
| 12 | openAccess |  | jul-2014 | Physical exercise neuroprotects ovariectomized 3xTg-AD mice through BDNF mechanisms | García-Mesa, Yoelvis CSIC; Pareja-Galeano, Helios; Bonet-Costa, Vicent; Revilla, Susana CSIC; Gómez-Cabrera, M. C.; Gambini, Juan Pablo; Giménez-Llort, Lydia; Cristòfol, Rosa CSIC ; Viña, J.; Sanfeliu, Coral CSIC ORCID | artículo |
| 13 | closedAccess |  | 2017 | Targeted nanoparticles for the treatment of Alzheimer's disease | Martín-Rapún, Rafael CSIC ORCID; Matteis, Laura de; Ambrosone, Alfredo; García-Embid, Sonia; Gutiérrez, Lucía CSIC ORCID; Fuente, Jesús M. de la CSIC ORCID | artículo |
| 14 | closedAccess |  | 2018 | Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, asmulti-target-directed ligands for Alzheimer's disease | Chioua, Mourad CSIC ORCID ; Buzzi, Eleonora; Moraleda, Ignacio; Iriepa, Isabel; Maj, Maciej; Wnorowski, Artur; Giovannini, Catia; Tamarin, Anna; Portali, Federica; Ismaili, Lhassane; López-Alvarado, Pilar; Bolognesi, Maria Laura; Jóźwiak, Krzysztof; Menéndez, J. Carlos; Marco-Contelles, José CSIC ORCID; Bartolini, Manuela | artículo |
| 15 | closedAccess |  | 2019 | Indazolylketones as new multitarget cannabinoid drugs | González-Naranjo, Pedro CSIC ORCID; Pérez-Macías, Natalia CSIC ORCID; Pérez, Concepción CSIC ORCID; Roca, Carlos CSIC ORCID; Vaca, Gabriela; Girón, Rocío CSIC ORCID; Sánchez-Robles, E. M. CSIC ORCID; Martín-Fontelles, M. I.; Ceballos, María L. de CSIC ORCID; Martín-Requero, Ángeles CSIC ORCID ; Campillo, Nuria E. CSIC ORCID ; Páez, Juan A. CSIC ORCID | artículo |
| 16 | closedAccess |  | jun-2014 | Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain | Revilla, Susana CSIC; Suñol, Cristina CSIC ORCID ; García-Mesa, Yoelvis CSIC; Giménez-Llort, Lydia; Sanfeliu, Coral CSIC ORCID; Cristòfol, Rosa CSIC | artículo |
| 17 | openAccess |  | 13-sep-2013 | Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia | Ruiz, Agustín; Dols-Icardo, Oriol; Bullido, María Jesús CSIC ORCID; Pastor, Pau; Rodríguez-Rodríguez, Eloy; López de Munain, Adolfo; de Pancorbo, Marian M.; Pérez-Tur, Jordi CSIC ORCID ; Álvarez, Victoria; Antonell, Anna; López-Arrieta, Jesús; Hernández, Isabel; Tárraga, Lluís; Boada, Mercè; Lleó, Alberto; Blesa, Rafael; Frank, Ana; Sastre, Isabel CSIC ORCID; Razquin, Cristina; Ortega-Cubero, Sara; Lorenzo, Elena; Sánchez-Juan, Pascual; Combarros, Onofre; Moreno, Fermín; Gorostidi, Ana; Baquero, Miquel; Coto, Eliecer; Sánchez-Valle, Raquel; Clarimón, Jordi | artículo |
| 18 | closedAccess |  | 2013 | G protein-coupled estrogen receptor is required for the neuritogenic mechanism of 17β-estradiol in developing hippocampal neurons | Ruiz-Palmero, Isabel CSIC; Hernando, M.; García-Segura, Luis M. CSIC ORCID; Arévalo, María Ángeles CSIC ORCID | artículo |
| 19 | openAccess |  | 4-feb-2011 | Inhibition of RhoA GTPase and the subsequent activation of PTP1B protects cultured hippocampal neurons against amyloid β toxicity | Chacón, Pedro J. CSIC; García-Mejías, Rosa CSIC; Rodríguez-Tebar, Alfredo CSIC | artículo |
| 20 | closedAccess |  | 2017 | A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer’s Disease Mice | Cuadrado-Tejedor, M.; Garcia-Barroso, Carolina; Sánchez-Arias, Juan A.; Rabal, Obdulia; Pérez-González, Marta; Mederos, Sara CSIC ORCID; Ugarte, Ana; Franco, Rafael; Segura, Víctor; Perea, Gertrudis CSIC ORCID; Oyarzabal, Julen; García-Osta, A. | artículo |
| 21 | closedAccess |  | 1-jul-2015 | Protective effect of sulfurous water in peripheral blood mononuclear cells of Alzheimer's disease patients | Guzmán Martínez, R.; Campos, Carlos CSIC; Yuguero, R.; Massegú Serrà, Cristina; Gil, P.; Casado Moragón, Ángela CSIC | artículo |
| 22 | closedAccess |  | 2019 | Tacrines for Alzheimer's disease therapy. III. The PyridoTacrines | Ríos, Cristóbal de los; Marco-Contelles, José CSIC ORCID | artículo |
| 23 | openAccess |  | 2019 | Innovative therapeutic potential of cannabinoid receptors as targets in Alzheimer’s disease and less well-known diseases | Páez, Juan A. CSIC ORCID; Campillo, Nuria E. CSIC ORCID | artículo |
| 24 | closedAccess |  | nov-2013 | Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice | Ramos-Rodríguez, Juan José; Ortiz, Óscar CSIC; Jiménez-Palomares, Margarita CSIC ORCID; Kay, Kevin R.; Berrocoso, Esther; Murillo-Carretero, Maria Isabel; Perdomo, Germán CSIC ORCID CVN; Spires-Jones, Tara; Cózar-Castellano, Irene CSIC ORCID CVN; Lechuga-Sancho, Alfonso María; García-Alloza, Mónica | artículo |
| 25 | openAccess |  | mar-2019 | Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization | Lapresa, Rebeca CSIC ORCID; Agulla, Jesús CSIC ORCID; Sánchez Morán, Irene CSIC ORCID; Zamarreño, Rubén; Prieto, Estefanía; Bolaños, Juan P. CSIC ORCID; Almeida, Angeles CSIC ORCID | artículo |
| 26 | closedAccess |  | 2015 | Recent advances and applications of metabolomics to investigate neurodegenerative diseases | Ibáñez, Clara CSIC; Cifuentes, Alejandro CSIC ORCID ; Simó, Carolina CSIC ORCID | capítulo de libro |
| 27 | closedAccess |  | feb-2015 | Cerebellin 4, a synaptic protein, enhances inhibitory activity and resistance of neurons to amyloid-ß toxicity | Chacón, Pedro J. CSIC; Marco, Ángel del; Arévalo, María Ángeles CSIC ORCID ; Domínguez Giménez, Paloma CSIC ORCID; García-Segura, Luis M. CSIC ORCID; Rodríguez-Tebar, Alfredo CSIC | artículo |
| 28 | closedAccess |  | 2013 | A new metabolomic workflow for early detection of Alzheimer's disease | Ibáñez, Clara CSIC; Simó, Carolina CSIC ORCID ; Cifuentes, Alejandro CSIC ORCID | artículo |
| 29 | closedAccess |  | 2015 | Astroglial cell subtypes in the cerebella of normal adults, elderly adults, and patients with Alzheimer's disease: a histological and immunohistochemical comparison. | Álvarez, M. Isabel; Rivas, Luis CSIC ORCID ; Lacruz, C.; Toledano Gasca, Adolfo CSIC ORCID CVN | artículo |
| 30 | openAccess |  | 1-feb-2011 | Physical exercise protects against alzheimer's disease in 3xTg-AD mice | García-Mesa, Yoelvis CSIC; López-Ramos, Juan Carlos; Giménez-Llort, Lydia; Revilla, Susana CSIC; Guerra, Rafael; Gruart, Agnès; LaFerla, Frank M.; Cristòfol, Rosa CSIC ; Delgado-García, José María CSIC; Sanfeliu, Coral CSIC ORCID | artículo |
| 31 | openAccess | | 20-oct-2017 | From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease | Chierrito, Talita P. C.; Roca, Carlos CSIC ORCID; Requena-Triguero, Carlos CSIC ORCID; Sebastián-Pérez, Víctor; Pérez, Concepción CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Cañada, F. Javier ; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Carvalho, Ivone | artículo |
| 32 | closedAccess |  | 2018 | The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca2+ dysregulation, and mitochondrial abnormalities | Martin-de-Saavedra, María; Navarro, Elisa; Moreno-Ortega, Ana J.; Cunha, Mauricio P.; Buendía Abaitua, Izaskun; Hernansanz-Agustín, Pablo; León, Rafael CSIC ORCID ; Cano-Abad, María F.; Martínez-Ruiz, Antonio CSIC ORCID; Martínez-Murillo, Ricardo CSIC ORCID; Duchen, Michael R.; López, Manuela G. | artículo |
| 33 | openAccess |  | 2019 | Nucleus–cytoplasm cross-talk in the aging brain | Benvegnú, Stefano CSIC ORCID | artículo |
| 34 | closedAccess |  | 2018 | Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors | Chierrito, Talita P. C.; Pedersoli-Mantoani, S.; Roca, Carlos CSIC ORCID; Sebastián-Pérez, Víctor; Martínez-González, Loreto CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Campillo, Nuria E. CSIC ORCID ; Carvalho, Ivone; Martínez Gil, Ana CSIC ORCID | artículo |
| 35 | closedAccess |  | 2016 | NRF2 in neurodegenerative diseases | Cuadrado, Antonio CSIC ORCID | artículo |
| 36 | closedAccess |  | 2018 | Is it all said for NSAIDs in Alzheimer’s disease? Role of mitochondrial calcium uptake | Sanz-Blasco, Sara CSIC; Calvo-Rodríguez, María CSIC ORCID; Caballero, Erica CSIC; García-Durillo, Mónica CSIC; Núñez, Lucía CSIC ORCID; Villalobos, Carlos CSIC ORCID | artículo |
| 37 | closedAccess |  | 2013 | Discrimination analysis of blood plasma associated with Alzheimer's disease using vibrational spectroscopy | Carmona, Pedro CSIC; Molina, Marina CSIC; Calero Lara, Miguel; Bermejo Pareja, Félix; Martínez-Martín, Pablo; Toledano Gasca, Adolfo CSIC ORCID CVN | artículo |
| 38 | closedAccess |  | 2013 | In vivo evaluation of amyloid deposition and brain glucose metabolism of 5XFAD mice using positron emission tomography | Rojas, Santiago CSIC; Perpiñá, Unai CSIC ORCID; Sarroca, Sara CSIC; Rodríguez, Elisenda CSIC; Sanfeliu, Coral CSIC ORCID | artículo |
| 39 | closedAccess |  | 2014 | Does Alzheimer's disease exist in all primates? Alzheimer pathology in non-human primates and its pathophysiological implications (II) | Toledano-Díaz, A. CSIC ORCID ; Álvarez, M. Isabel; López-Rodríguez, A. B. CSIC ORCID; Toledano-Díaz, A. CSIC ORCID ; Fernández-Verdecia, Caridad Ivette | artículo |
| 40 | openAccess | | 28-dic-2018 | Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease | De Andrade, Peterson; Mantoani, Susimaire P.; Gonçalves Nunes, Paulo Sérgio; Roca, Carlos CSIC ORCID; Pérez, Concepción CSIC ORCID; Xavier, Danilo Jordão; Hojo, Elza Tiemi Sakamoto; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Carvalho, Ivone | artículo |
| 41 | openAccess |  | 2011 | TNF-α Contributes to Caspase-3 Independent Apoptosis in Neuroblastoma Cells: Role of NFAT | Álvarez Losada, Susana; Blanco, Almudena; Fresno, Manuel CSIC ORCID ; Muñoz-Fernández, María Ángeles CSIC ORCID | artículo |
| 42 | closedAccess |  | 2011 | Overcoming cell death and tau phosphorylation mediated by PI3K-inhibition: a cell assay to measure neuroprotection. | Simón, Diana CSIC ORCID; Medina, Miguel CSIC ORCID; Ávila, Jesús CSIC ORCID ; Wandosell, Francisco CSIC ORCID | artículo |
| 43 | closedAccess |  | 2014 | N-(furan-2-ylmethyl)-N-methylprop-2-yn-1-amine (F2MPA): A potential cognitive enhancer with MAO inhibitor properties | Di Giovanni, Giuseppe; García, Isela; Colangeli, Roberto; Pierucci, Massimo; Rivadulla, Marcos L.; Soriano, Elena CSIC; Chioua, Mourad CSIC ORCID ; Della Corte, Laura; Yáñez, Matilde; De Deurwaerdère, Phillippe; Fall, Yagamare; Marco-Contelles, José CSIC ORCID | artículo |
| 44 | closedAccess |  | 25-jul-2012 | Retromer Regulates Postendocytic Sorting of β-Secretase in Polarized Madin–Darby Canine Kidney Cells | Cuartero, Yasmina; Mellado, Maravillas; Capell, Anja; Álvarez-Dolado, Manuel CSIC ORCID CVN; Verges, Marcel | artículo |
| 45 | openAccess |  | 20-ago-2018 | Dephosphorylated rather than hyperphosphorylated Tau triggers a pro-inflammatory profile in microglia through the p38 MAPK pathway | Perea, Juan Ramón; Ávila, Jesús CSIC ORCID ; Bolós, Marta CSIC ORCID | artículo |
| 46 | closedAccess |  | 2017 | Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy | Dgachi, Youssef; Sokolov, O.; Luzet, V.; Godyn, J.; Panek, D.; Bonet, A.; Martin, Helene; Iriepa, Isabel; Moraleda, I.; García-Iriepa, C.; Janockova, J.; Richert, L.; Soukup, O.; Malawska, B.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, L. | artículo |
| 47 | closedAccess |  | 2017 | Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function | Mendivil-Perez, Miguel; Capilla-González, Vivian CSIC ORCID; García Verdugo, José M.; Escames, Germaine | artículo |
| 48 | openAccess |  | 2012 | Noninvasive molecular imaging of neuroinflammation | Jacobs, Andreas H.; Tavitian, Bertrand; Planas, Anna M. CSIC ORCID | artículo |
| 49 | openAccess |  | 15-feb-2012 | The Characterization of the Caenorhabditis elegans Mitochondrial Thioredoxin System Uncovers an Unexpected Protective Role of Thioredoxin Reductase 2 in β-Amyloid Peptide Toxicity | Cacho-Valadez, Briseida CSIC; Muñoz-Lobato, Fernando CSIC; Pedrajas, José R.; Cabello, Juan CSIC ORCID; Fierro-González, Juan Carlos; Navas, Plácido CSIC ORCID; Swoboda, Peter; Link, Chris D.; Miranda-Vizuete, Antonio CSIC ORCID | artículo |
| 50 | openAccess |  | 7-may-2018 | PM20D1 is a quantitative trait locus associated with Alzheimer's disease | Sánchez-Mut, José V.; Heyn, Holger; Silva, Bianca Ambrogina; Dixsaut, Lucie; García-Esparcia, Paula; Vidal, Enrique; Sayols, Sergi; Glauser, Liliane; Monteagudo-Sánchez, Ana; Pérez-Tur, Jordi CSIC ORCID ; Ferrer, Isidro; Monk, David; Schneider, Bernard; Esteller, Manel; Gräff, Johannes | artículo |
