Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/34659COMPARTIR / EXPORTAR:
 SHARE
 CORE
BASE
|
|
| Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
| Título: | An exploratory NMR nutri-metabonomic investigation reveals dimethyl sulfone as a dietary biomarker for onion intake |
Autor: | Winning, Hanne; Roldán-Marín, Eduvigis; Sánchez-Moreno, Concepción CSIC ORCID ; Cano, M. Pilar CSIC ORCID ; Engelsen, Søren B. | Fecha de publicación: | 2009 | Editor: | Royal Society of Chemistry (UK) | Citación: | Analyst 134(11): 2344-2351 (2009) | Resumen: | The metabolome following intake of onion by-products is evaluated. Thirty-two rats were fed a diet containing an onion by-product or one of the two derived onion by-product fractions: an ethanol extract and the residue. A 24 hour urine sample was analyzed using 1H NMR spectroscopy in order to investigate the effects of onion intake on the rat metabolism. Application of interval extended canonical variates analysis (ECVA) proved to be able to distinguish between the metabolomic profiles from rats consuming normal feed and rats fed with an onion diet. Two dietary biomarkers for onion intake were identified as dimethyl sulfone and 3-hydroxyphenylacetic acid. The same two dietary biomarkers were subsequently revealed by interval partial least squares regression (PLS) to be perfect quantitative markers for onion intake. The best PLS calibration model yielded a root mean square error of cross-validation (RMSECV) of 0.97% (w/w) with only 1 latent variable and a squared correlation coefficient of 0.94. This indicates that urine from rats on the by-product diet, the extract diet, and the residue diet all contain the same dietary biomarkers and it is concluded that dimethyl sulfone and 3-hydroxyphenylacetic acid are dietary biomarkers for onion intake. Being able to detect specific dietary biomarkers is highly beneficial in the control of nutritionally enhanced functional foods. | Descripción: | 8 páginas, 7 figuras, 1 tabla.-- et al. | Versión del editor: | http://dx.doi.org/10.1039/B918259D | URI: | http://hdl.handle.net/10261/34659 | DOI: | 10.1039/B918259D | ISSN: | 0003-2654 |
| Aparece en las colecciones: | (IF) Artículos |
Mostrar el registro completo
CORE Recommender
WEB OF SCIENCETM
Citations
44
checked on 29-feb-2024
Page view(s)
421
checked on 02-may-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.