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Título: | A comprehensive study on the chemical characterization and neuroprotective evaluation of pracaxi nuts extracts obtained by a sustainable approach |
Autor: | Mohammadnezhad, Pouya CSIC ORCID; Valdés, Alberto CSIC ORCID; Barrientos, Ruth E.; Ibáñez, Elena CSIC ORCID ; Block, Jane Mara; Cifuentes, Alejandro CSIC ORCID | Palabras clave: | Green extraction Neuroprotective activity Pracaxi nuts Pressurized liquid extraction Ppermidine phenolamides Triterpenoid saponins |
Fecha de publicación: | 23-oct-2023 | Editor: | Multidisciplinary Digital Publishing Institute | Citación: | Foods 12(20): 3879 (2023) | Resumen: | The Amazonian Pentaclethra macroloba (Willd.) Kuntze nuts contain a lipidic fraction with health-promoting effects, but little is known about the bioactivity of other constituents. In this study, the lipidic fraction obtained using supercritical fluid extraction (SFE) with CO2 was chemically characterized by using lipidomics techniques. The SFE-CO2 residue, named as pracaxi cake, was re-extracted by pressurized liquid extraction following a biorefinery approach. Using a response surface methodology and based on the extraction yield and different in vitro assays, two optimum conditions were obtained: 80% and 12.5% of ethanol at 180 °C. Under these conditions, extraction yield and different in vitro measurements related to neuroprotection were assessed. Chemical characterization of these extracts suggested the presence of triterpenoid saponins and spermidine phenolamides, which were not previously reported in pracaxi nuts. These results suggest that pracaxi oil extraction by-products are a valuable source of bioactive compounds with neuroprotective potential. | Versión del editor: | https://doi.org/10.3390/foods12203879 | URI: | http://hdl.handle.net/10261/338332 | DOI: | 10.3390/foods12203879 | E-ISSN: | 2304-8158 |
Aparece en las colecciones: | (CIAL) Artículos |
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