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| Título: | Vitamin E prevents lipid peroxidation and iron accumulation in PLA2G6-Associated Neurodegeneration |
Autor: | Villalón-García, Irene; Álvarez-Córdoba, Mónica; Povea-Cabello, Suleva; Talaverón-Rey, Marta; Villanueva-Paz, Marina CSIC ORCID; Luzón-Hidalgo, Raquel CSIC ORCID; Suarez-Rivero, Juan M. CSIC ORCID; Suárez-Carrillo, Alejandra; Munuera, Manuel CSIC; Salas, Joaquín J. CSIC ORCID ; Falcón-Moya, Rafael; Rodríguez-Moreno, Antonio CSIC ORCID; Armengol, José A.; Sánchez-Alcázar, José Antonio CSIC ORCID | Palabras clave: | Iron accumulation Lipid peroxidation Lipofuscin Mitochondria NBIA PLA2G6-Associated Neurodegeneration Vitamin E |
Fecha de publicación: | abr-2022 | Editor: | Elsevier | Citación: | Neurobiology of Disease 165: 105649 (2022) | Resumen: | PLA2G6-Associated Neurodegeneration (PLAN) is a rare neurodegenerative disease with autosomal recessive inheritance, which belongs to the NBIA (Neurodegeneration with Brain Iron Accumulation) group. Although the pathogenesis of the disease remains largely unclear, lipid peroxidation seems to play a central role in the pathogenesis. Currently, there is no cure for the disease. | Descripción: | 23 Páginas.-- 17 Figuras | Versión del editor: | https://doi.org/10.1016/j.nbd.2022.105649 | URI: | http://hdl.handle.net/10261/264896 | DOI: | 10.1016/j.nbd.2022.105649 | ISSN: | 0969-9961 |
| Aparece en las colecciones: | (IG) Artículos (CABD) Artículos |
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| Neurobiol_Dis_2022_V165_105649.pdf | Artículo principal | 11,58 MB | Adobe PDF |  Visualizar/Abrir |
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