Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/194927
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Mitochondria-encoded genes contribute to evolution of heat and cold tolerance in yeast |
Autor: | Li, Xueying C.; Peris Navarro, David CSIC ORCID CVN; Hittinger, Chris Todd; Sia, Elaine A.; Fay, Justin C. | Fecha de publicación: | ene-2019 | Editor: | American Association for the Advancement of Science | Citación: | Science Advances 5(1): eaav1848 (2019) | Resumen: | Genetic analysis of phenotypic differences between species is typically limited to interfertile species. Here, we conducted a genome-wide noncomplementation screen to identify genes that contribute to a major difference in thermal growth profile between two reproductively isolated yeast species, Saccharomyces cerevisiae and Saccharomyces uvarum. The screen identified only a single nuclear-encoded gene with a moderate effect on heat tolerance, but, in contrast, revealed a large effect of mitochondrial DNA (mitotype) on both heat and cold tolerance. Recombinant mitotypes indicate that multiple genes contribute to thermal divergence, and we show that protein divergence in COX1 affects both heat and cold tolerance. Our results point to the yeast mitochondrial genome as an evolutionary hotspot for thermal divergence. | Versión del editor: | https://doi.org/10.1126/sciadv.aav1848 | URI: | http://hdl.handle.net/10261/194927 | DOI: | 10.1126/sciadv.aav1848 | E-ISSN: | 2375-2548 |
Aparece en las colecciones: | (IATA) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Xueying_et_al_2018.pdf | 1,68 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
37
checked on 11-abr-2024
SCOPUSTM
Citations
57
checked on 06-may-2024
WEB OF SCIENCETM
Citations
49
checked on 21-feb-2024
Page view(s)
202
checked on 12-may-2024
Download(s)
174
checked on 12-may-2024