1. DIGITAL.CSIC

Matesanz, Ruth

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Firma en Digital.CSIC (*)
Matesanz, Ruth
 
Centro o Instituto
CSIC - Centro de Investigaciones Biologicas Margarita Salas (CIB)
 
Departamento
Servicios científicos
 
Especialización
Bioinformática y Bioestadística
 
Email
ruth.m.r@cib.csic.es
 
Scopus AuthorID
 

Publications

Refined By:
Autor:  Díaz, José Fernando

Resultados 1-20 de 21.

DerechosPreviewFecha Public.TítuloAutor(es)Tipo
1openAccesstubulin_binding_Coderch.pdf.jpgmar-2013A structure-based design of new C2- and C13-substituted taxanes: Tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysisCoderch, Claire; Tang, Yong; Klett, Javier CSIC ORCID; Zhang, Shu-En; Ma, Yung-Tao; Shaorong, Wang; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Morreale, Antonio; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.; Gago, Federico CSIC ORCIDartículo
2closedAccess2007Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studiesLa Regina, Giuseppe; Edler, Michael C.; Brancale, Andrea; Kandil, Sahar; Coluccia, Antonio; Piscitelli, Francesco; Hamel, Ernest; De Martino, Gabriella; Matesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Scovassi, Anna Ivana; Prosperi, Ennio; Lavecchia, Antonio; Novellino, Ettore; Artico, Marino; Silvestri, Romanoartículo
3openAccesscyclostreptin_Buey.pdf.jpgene-2007Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sitesMartínez Buey, Rubén CSIC ORCID; Calvo, Enrique; Barasoain, Isabel CSIC ; Pineda, Oriol; Edler, Michael C.; Matesanz, Ruth CSIC ; Cerezo, Gemma; Vanderwal, Christopher D.; Day, Billy W.; Sorensen, Erik J.; López, Juan Antonio; Andreu, José Manuel CSIC ORCID ; Hamel, Ernest; Díaz, José Fernando CSIC ORCID artículo
4closedAccessrestringido.pdf.jpgene-2012Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel SiteCalvo, Enrique; Barasoain, Isabel CSIC ; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Camafeita, Emilio; Pineda, Oriol; Hamel, Ernest; Vanderwal, Christopher D.; Andreu, José Manuel CSIC ORCID ; López, Juan Antonio; Díaz, José Fernando CSIC ORCID artículo
5closedAccessrestringido.pdf.jpg5-oct-2009Epothilone Analogs with Benzimidazole and Quinoline Side Chains: Chemical Synthesis, Antiproliferative Activity, and Interactions with TubulinDietrich, Silvia Anthoine; Lindauer, Renate; Stierling, Claire; Gertsch, Jürg; Matesanz, Ruth CSIC ; Notararigo, Sara CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinzartículo
6openAccessMatesanz_et_al_2011 Biophysical Journal.pdf.jpg21-dic-2011Modulation of microtubule interprotofilament interactions by modified taxanesMatesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier CSIC; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Bras, Wim; Nogales, Aurora CSIC ORCID; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID artículo
7embargoedAccessEuropean Journal of Medicinal Chemistry_Ma et al._2023.pdf.jpg5-nov-2023Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potencyMa, Yuntao; Josa-Prado, Fernando CSIC ORCID; Essif, Jacob Nathaniel; Liu, Shuqi; Li, Shuo; Lucena-Agell, Daniel CSIC ORCID ; Chan, Peter; Goossens, Kenneth; Hortigüela, Rafael CSIC ORCID; Matesanz, Ruth CSIC ; Wang, Yingjie; Gago, Federico CSIC ORCID; Wang, Hongbo; Risinger, April L.; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuoartículo
8closedAccessrestringido.pdf.jpg5-mar-2012Multiple keys for a single lock: the unusual structural plasticity of the Nucleotidyltransferase (4’)/kanamycin complex ChemistryMatesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Corzana, Francisco; Santana, Andrés G. CSIC ORCID ; Bastida, Agatha CSIC ORCID ; Asensio, Juan Luis CSIC ORCIDartículo
9closedAccessaccesoRestringido.pdf.jpg16-jul-2013New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanismPera, Benet CSIC; Barasoain, Isabel CSIC ; Pantazopoulou, Areti CSIC ORCID; Canales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier CSIC; García-Fernández, Luis F. CSIC; Moneo, Victoria; Jiménez-Barbero, Jesús CSIC ORCID; Galmarini, Carlos M.; Cuevas, Carmen; Peñalva, Miguel Ángel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Andreu, José Manuel CSIC ORCID artículo
10closedAccessMatesanz et al-2008_Chemistry and Biology.pdf.jpg23-jun-2008Optimization of Taxane Binding to Microtubules: Binding Affinity Dissection and Incremental Construction of a High-Affinity Analog of PaclitaxelMatesanz, Ruth CSIC ; Barasoain, Isabel CSIC ; Yang, Chun-Gang; Wan, L.; Li, Xuan; Inés, Concepción de CSIC; Coderch, Claire; Gago, Federico CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID artículo
11closedAccessaccesoRestringido.pdf.jpg14-may-2007Overcoming tumor drug resistance with high-affinity taxanes: A SAR study of C2-modified 7-acyl-10-deacetyl cephalomanninesYang, Chun-Gang; Barasoain, Isabel CSIC ; Li, Xuan; Matesanz, Ruth CSIC ; Liu, Ronghua; Sharom, Frances J.; Yin, Da-Li; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuoartículo
12openAccessjournal of medicinal chemistry_lucena-agell_2024.pdf.jpg31-ene-2024PM534, an optimized target-protein interaction strategy through the colchicine site of tubulinLucena-Agell, Daniel CSIC ORCID ; Guillén, María José; Matesanz, Ruth CSIC ; Álvarez-Bernad, Beatriz CSIC; Hortigüela, Rafael CSIC ORCID; Avilés, Pablo; Martínez-Díez, Marta; Santamaría, Gema; Contreras, Julia CSIC; Plaza-Menacho, Iván; Giménez-Abián, Juan F. CSIC ; Oliva, María A. CSIC ORCID ; Cuevas, Carmen; Díaz, José Fernando CSIC ORCID artículo
13closedAccessaccesoRestringido.pdf.jpg26-mar-2010Probing the Pore Drug Binding Site of Microtubules with Fluorescent Taxanes: Evidence of Two Binding PosesBarasoain, Isabel CSIC ; García-Carril, Ana M.; Matesanz, Ruth CSIC ; Maccari, Giorgio; Trigili, Chiara CSIC; Mori, Mattia; Shi, Jing-Zhe; Fang, Wei-Shuo; Andreu, José Manuel CSIC ORCID ; Botta, Maurizio; Díaz, José Fernando CSIC ORCID artículo
14closedAccessaccesoRestringido.pdf.jpg1-feb-2009Synthesis and biological activities of high affinity taxane-based fluorescent probesLi, Xuan; Barasoain, Isabel CSIC ; Matesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuoartículo
15closedAccessaccesoRestringido.pdf.jpg1-jun-2007Synthesis, biological evaluations, and tubulin binding poses of C-2α sulfur linked taxol analoguesWang, Lei; Alcaraz, Ana A.; Matesanz, Ruth CSIC ; Yang, Chun-Gang; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Li, Ye-Zhi; Snyder, James P.; Fang, Wei-Shuoartículo
16openAccessmolecules-2016.pdf.jpg3-ago-2016Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones)Jantsch, Andrea; Nieto, Lidia CSIC; Gertsch, Jürg; Rodríguez-Salarichs, Javier CSIC; Matesanz, Ruth CSIC ; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Canales, Ángeles CSIC ORCID; Altmann, Karl-Heinzartículo
17openAccessMatesanz et al_2014 _Bioorganic Medicinal Chemistry.pdf.jpg19-jun-2014Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistancesMatesanz, Ruth CSIC ; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier CSIC; Pera, Benet CSIC; Jiménez-Barbero, Jesús CSIC ORCID; Canales, Ángeles CSIC ORCID; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID artículo
18closedAccessrestringido.pdf.jpgago-2008The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatinCanales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Gardner, Nicola M.; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCIDartículo
19closedAccessrestringido.pdf.jpg15-jun-2007The Total Synthesis and Biological Properties of the Cytotoxic Macrolide FD-891 and Its Non-Natural (Z)-C12 IsomerGarcía-Fortanet, Jorge; Murga, Juan; Carda, Miguel; Marco, J. Alberto; Matesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC artículo
20openAccessSaez-Calvo-et-al.2017.pdf.jpg22-jun-2017Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of TubulinSáez-Calvo, Gonzalo CSIC; Balaguer, Francisco de Asís CSIC ORCID; Barasoain, Isabel CSIC ; Rodríguez-Salarichs, Javier CSIC; Muñoz-Hernández, Hugo CSIC ORCID; Berbís, Manuel Álvaro CSIC; Peñalva, Miguel Ángel CSIC ORCID ; Matesanz, Ruth CSIC ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID artículo