Rights | Preview | Issue Date | Title | Author(s) | Type |
openAccess |  | Mar-2013 | A structure-based design of new C2- and C13-substituted taxanes: Tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis | Coderch, Claire; Tang, Yong; Klett, Javier ; Zhang, Shu-En; Ma, Yung-Tao; Shaorong, Wang; Matesanz, Ruth ; Pera, Benet ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Morreale, Antonio ; Díaz, José Fernando ; Fang, Wei-shuo S.; Gago, Federico  | artículo |
closedAccess | | 2007 | Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies | La Regina, Giuseppe; Edler, Michael C.; Brancale, Andrea; Kandil, Sahar; Coluccia, Antonio; Piscitelli, Francesco; Hamel, Ernest; De Martino, Gabriella; Matesanz, Ruth ; Díaz, José Fernando ; Scovassi, Anna Ivana; Prosperi, Ennio; Lavecchia, Antonio; Novellino, Ettore; Artico, Marino; Silvestri, Romano | artículo |
openAccess |  | Jan-2007 | Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites | Buey, Ruben M.; Calvo, Enrique; Barasoain, Isabel ; Pineda, Oriol; Edler, Michael C.; Matesanz, Ruth ; Cerezo, Gemma; Vanderwal, Christopher D.; Day, Billy W.; Sorensen, Erik J.; López, Juan Antonio; Andreu, José Manuel ; Hamel, Ernest; Díaz, José Fernando | artículo |
closedAccess |  | Jan-2012 | Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel Site | Calvo, Enrique; Barasoain, Isabel ; Matesanz, Ruth ; Pera, Benet ; Camafeita, Emilio; Pineda, Oriol; Hamel, Ernest; Vanderwal, Christopher D.; Andreu, José Manuel ; López, Juan Antonio; Díaz, José Fernando | artículo |
closedAccess |  | 5-Oct-2009 | Epothilone Analogs with Benzimidazole and Quinoline Side Chains: Chemical Synthesis, Antiproliferative Activity, and Interactions with Tubulin | Dietrich, Silvia Anthoine; Lindauer, Renate; Stierling, Claire; Gertsch, Jürg; Matesanz, Ruth ; Notararigo, Sara ; Díaz, José Fernando ; Altmann, Karl-Heinz | artículo |
closedAccess |  | Mar-2015 | Identification and characterization of carboxyl esterases of gill chamber-associated microbiota in the deep-sea shrimp Rimicaris exoculata by using functional metagenomics | Alcaide, María ; Tchigvintsev, Anatoli; Martínez-Martínez, Mónica ; Popovic, Ana; Reva, Oleg; Lafraya Aguado, Álvaro ; Bargiela, Rafael ; Nechitaylo, Taras Y.; Matesanz, Ruth ; Cambon-Bonavita, M. A.; Jebbar, M.; Yakimov, Michail M.; Savchenko, Alexei; Golyshina, Olga V. ; Yakunin, Alexander F.; Golyshin, Peter N.; Ferrer, Manuel  | artículo |
openAccess |  | 21-Dec-2011 | Modulation of microtubule interprotofilament interactions by modified taxanes | Matesanz, Ruth ; Rodríguez-Salarichs, Javier; Pera, Benet ; Canales, Ángeles ; Andreu, José Manuel ; Jiménez-Barbero, Jesús ; Bras, Wim; Nogales, Aurora ; Fang, Wei-shuo S.; Díaz, José Fernando | artículo |
openAccess |  | 9-Oct-2015 | Molecular adaptation of Lactobacillus plantarum WCFS1 to gallic acid revealed by genome‑scale transcriptomic signature and physiological analysis | Reverón, Inés ; Rivas, Blanca de las ; Matesanz, Ruth ; Muñoz, Rosario ; López de Felipe, Félix  | artículo |
closedAccess |  | 5-Mar-2012 | Multiple keys for a single lock: the unusual structural plasticity of the Nucleotidyltransferase (4’)/kanamycin complex Chemistry | Matesanz, Ruth ; Díaz, José Fernando ; Corzana, Francisco; Santana, Andrés G. ; Bastida, Agatha ; Asensio, Juan Luis  | artículo |
openAccess |  | 2009 | Optimización de la interacción microtúbulo-taxol: Diseño de taxanos de alta afinidad | Matesanz, Ruth | tesis doctoral |
closedAccess |  | 23-Jun-2008 | Optimization of Taxane Binding to Microtubules: Binding Affinity Dissection and Incremental Construction of a High-Affinity Analog of Paclitaxel | Matesanz, Ruth ; Barasoain, Isabel ; Yang, C.G.; Wan, L.; Li, X.; Inés, C. de; Coderch, Claire; Gago, Federico ; Jiménez-Barbero, Jesús ; Andreu, José Manuel ; Fang, Wei-shuo S.; Díaz, José Fernando | artículo |
openAccess |  | 3-Aug-2016 | Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones) | Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Canales, Ángeles ; Altmann, Karl-Heinz | artículo |
openAccess |  | 3-Aug-2016 | Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones) | Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Canales, Ángeles ; Altmann, Karl-Heinz | artículo |
openAccess |  | 19-Jun-2014 | Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances | Matesanz, Ruth ; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Pera, Benet ; Jiménez-Barbero, Jesús ; Canales, Ángeles ; Barasoain, Isabel ; Díaz, José Fernando | artículo |
closedAccess |  | Aug-2008 | The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatin | Canales, Ángeles ; Matesanz, Ruth ; Gardner, Nicola M.; Andreu, José Manuel ; Paterson, Ian; Díaz, José Fernando ; Jiménez-Barbero, Jesús  | artículo |
closedAccess |  | 15-Jun-2007 | The Total Synthesis and Biological Properties of the Cytotoxic Macrolide FD-891 and Its Non-Natural (Z)-C12 Isomer | García-Fortanet, Jorge
Isabel Barasoain; Murga, Juan; Carda, Miguel; Marco, J. Alberto; Matesanz, Ruth ; Díaz, José Fernando ; Barasoain, Isabel  | artículo |
openAccess |  | Nov-2011 | Thermodynamics as a Tool for the Optimization of Drug Binding, Thermodynamics - Interaction Studies - Solids, Liquids and Gases | Matesanz, Ruth ; Pera, Benet ; Díaz, José Fernando | capítulo de libro |
openAccess |  | 22-Jun-2017 | Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin | Sáez-Calvo, Gonzalo; Balaguer, Francisco de Asís; Barasoain, Isabel ; Rodríguez-Salarichs, Javier; Muñoz-Hernández, Hugo; Berbís, Manuel Álvaro ; Peñalva, Miguel Ángel ; Matesanz, Ruth ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Andreu, José Manuel ; Díaz, José Fernando | artículo |
openAccess |  | 22-Jun-2012 | Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubules | Field, Jessica J.; Pera, Benet ; Calvo, Enrique; Canales, Ángeles ; Zurwerra, Didier; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús ; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel ; Altmann, Karl-Heinz; Díaz, José Fernando | artículo |