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Lucena-Agell, Daniel

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Perfil

Firma en Digital.CSIC (*)
Lucena-Agell, Daniel
 
Centro o Instituto
CSIC - Centro de Investigaciones Biologicas Margarita Salas (CIB)
 
Departamento
Biología Estructural y Química
 
Especialización
Agentes estabilizantes de microtúbulos
 
Email
lucena@cib.csic.es
 
ORCID
 
WoS ResearcherID - Publons
 
Scopus AuthorID
 
Otros - ResearchGate
 

Publications

Results 1-20 of 27 (Search time: 0.038 seconds).

RightsPreviewIssue DateTitleAuthor(s)Type
1openAccessNature Communications_Menchon_2018.pdf.jpg29-May-2018A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulinMenchon, Grégory; Lucena-Agell, Daniel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.artículo
2closedAccessaccesoRestringido.pdf.jpg26-Aug-2016Aggregated compound biological signatures facilitate phenotypic drug discovery and target elucidationCortés Cabrera, Álvaro CSIC ORCID; Lucena-Agell, Daniel CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fasching, Bernhard; Petrone, Paula M.artículo
3openAccessEukaryotic Cell-2015-Lucena-Agell-545-53.pdf.jpgJun-2015Aspergillus nidulans ambient pH signaling does not require endocytosisLucena-Agell, Daniel CSIC ORCID ; Galindo, Antonio CSIC ORCID; Arst, Herbert Nathan Jr. CSIC ; Peñalva, Miguel Ángel CSIC ORCID artículo
4openAccessStructure_Estévez-Gallego_2022.pdf.jpg5-Jan-2023Chemical modulation of microtubule structure through the laulimalide/peloruside siteEstévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Benet, Pera; Wullschleger, Christoph; Raes, Olivier; Menche, Dirk; Martínez, Juan Carlos; Lucena-Agell, Daniel CSIC ORCID ; Prota, Andrea E.; Bonato, Francesca CSIC ORCID; Bargsten, Katja; Cornelus, Jelle; Giménez-Abián, Juan F. CSIC ; Northcote, Peter; Steinmetz, Michel O.; Kamimura, Shinji; Altmann, Karl-Heinz; Paterson, Ian; Gago, Federico CSIC ORCID; Van der Eycken, Johan; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID artículo
5embargoedAccessEuropean Journal of Medicinal Chemistry_Campiani_2022.pdf.jpg5-May-2022Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacyCampiani, Giuseppe; Khan, Tuhina; Ulivieri, Cristina; Staiano, Leopoldo; Papulino, Chiara; Magnano, Stefania; Nathwani, Seema; Ramunno, Anna; Lucena-Agell, Daniel CSIC ORCID ; Relitti, Nicola; Federico, Stefano; Pozzetti, Luca; Carullo, Gabriele; Casagni, Alice; Brogi, Simone; Vanni, Francesca; Galatello, Paola; Ghanim, Magda; McCabe, Niamh; Lamponi, Stefania; Valoti, M.; Ibrahim, Ola; O'Sullivan, Jeff; Turkington, Richard; Kelly, Vincent P.; VanWemmel, Ruben; Díaz, José Fernando CSIC ORCID ; Gemma, Sandra; Zisterer, Daniela M.; Altucci, Lucia; De Matteis, Antonella; Butini, Stefania; Benedetti, Rosariaartículo
6closedAccessaccesoRestringido.pdf.jpg6-Oct-2021Design, synthesis, and in vitro evaluation of tubulin-targeting dibenzothiazines with antiproliferative activity as a novel heterocycle building blockGuerra, Walter D.; Lucena-Agell, Daniel CSIC ORCID ; Hortigüela, Rafael CSIC ORCID; Rossi, Roberto A.; Díaz, José Fernando CSIC ORCID ; Padrón, José M.; Barolo, Silvia M.artículo
7openAccessijms-23-03448-v2.pdf.jpg22-Mar-2022Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport FunctionOliva, María A. CSIC ORCID ; Tosat-Bitrian, Carlota CSIC ORCID ; Barrado-Gil, Lucía CSIC ORCID; Bonato, Francesca CSIC ORCID; Galindo Barreales, Inmaculada; Garaigorta, Urtzi ; Álvarez-Bernad, Beatriz CSIC; París-Ogáyar, Rebeca CSIC ORCID; Lucena-Agell, Daniel CSIC ORCID ; Giménez-Abián, Juan F. CSIC ; García-Dorival, Isabel; Urquiza, Jesús; Gastaminza, Pablo CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Palomo, Valle CSIC ORCID ; Alonso Martí, Covadongaartículo
8openAccessPNAS_Matthew_2020.pdf.jpg2-Mar-2021Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological siteMatthew, S.; Chen, Qi-Yin; Ratnayake, R.; Fermaintt, Charles S.; Lucena-Agell, Daniel CSIC ORCID ; Bonato, Francesca CSIC ORCID; Prota, Andrea E.; Lim, Seok Ting; Wang, Xiaomeng; Díaz, José Fernando CSIC ORCID ; Risinger, April L.; Paul, Valerie J.; Oliva, María A. CSIC ORCID ; Luesch, H.artículo
9openAccessBioorganic Chemistry_Nemati_2021.pdf.jpg30-Jun-2021Identification of novel anti-cancer agents by the synthesis and cellular screening of a noscapine-based libraryNemati, Faezeh; Bischoff-Kont, Iris; Salehi, Peyman; Nejad-Ebrahimi, Samad; Mohebbi, Maryam; Bararjanian, Morteza; Hadian, Nasim; Hassanpour, Zahra; Jung, Yvonne; Schaerlaekens, Sofie; Lucena-Agell, Daniel CSIC ORCID ; Oliva, María A. CSIC ORCID ; Fürst, Robert; Nasiri, Hamid R.artículo
10openAccessPNAS_.Unterhauser_2019.pdf.jpg26-Feb-2019Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubulestabilizing activitiesUnterhauser, Katrin; Poltl, Lisa; Schneditz, Georg; Kienesberger, Sabine; Glabonjat, Ronald A.; Kitsera, Maksym; Pletz, Jakob; Josa-Prado, Fernando CSIC ORCID; Dornisch, Elisabeth; Lembacher-Fadum, Christian; Roier, Sandro; Gorkiewicz, Gregor; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Kroutil, Wolfgang; Wiedner, Marc; Loizou, Joanna I.; Breinbauer, Rolf; Díaz, José Fernando CSIC ORCID ; Schild, Stefan; Hog̈enauer, Christoph; Zechner, Ellen L.artículo
11openAccesschemistry_marzullo_2021.pdf.jpgNov-2021Maytansinol derivatives: side reactions as a chance for new tubulin bindersMarzullo, Paola; Boiarska, Zlata; Pérez-Peña, Helena; Abel, Anne-Catherine; Álvarez-Bernad, Beatriz CSIC; Lucena-Agell, Daniel CSIC ORCID ; Vasile, Francesca; Sironi, Maurizio; Altmann, Karl-Heinz; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID ; Pieraccini, Stefano; Passarella, D.artículo
12closedAccessaccesoRestringido.pdf.jpg24-Jan-2023Maytansinol functionalization:towards useful probes for studying microtubule dynamicsBoiarska, Zlata; Pérez-Peña, Helena; Abel, Anne-Catherine; Marzullo, Paola; Álvarez-Bernad, Beatriz CSIC; Bonato, Francesca CSIC ORCID; Santini, Benedetta; Horvath, Dragos; Lucena-Agell, Daniel CSIC ORCID ; Vasile, Francesca; Sironi, Maurizio; Díaz, José Fernando CSIC ORCID ; Prota, Andrea E.; Pieraccini, Stefano; Passarella, D.artículo
13openAccess2017 Tang et al.pdf.jpg3-Jun-2017Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.Tang, Yong; Rodríguez-Salarichs, Javier CSIC; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuoartículo
14embargoedAccessEuropean Journal of Medicinal Chemistry_Ma et al._2023.pdf.jpg5-Nov-2023Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potencyMa, Yuntao; Josa-Prado, Fernando CSIC ORCID; Essif, Jacob Nathaniel; Liu, Shuqi; Li, Shuo; Lucena-Agell, Daniel CSIC ORCID ; Chan, Peter; Goossens, Kenneth; Hortigüela, Rafael CSIC ORCID; Matesanz, Ruth CSIC ; Wang, Yingjie; Gago, Federico CSIC ORCID; Wang, Hongbo; Risinger, April L.; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuoartículo
15openAccessLucena-Agell_et_al-2016-Molecular_Microbiology.pdf.jpg15-Jul-2016Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compoundsLucena-Agell, Daniel CSIC ORCID ; Hervás-Aguilar, América CSIC; Múnera-Huertas, Tatiana; Pougovkina, Olga; Rudnicka, Joanna D.; Galindo, Antonio CSIC ORCID; Tilburn, Joan; Arst, Herbert Nathan Jr. CSIC ; Peñalva, Miguel Ángel CSIC ORCID artículo
16openAccessCancer Cell International_Keenan_2020.pdf.jpg2020N‑alkylisatin‑based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicityKeenan, Bryce; Finol-Urdaneta, Rocío; Hope, Ashleigh; Bremner, John B.; Kavallaris, Maria; Lucena-Agell, Daniel CSIC ORCID ; Oliva, María A. CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Vine, Kara L.artículo
17openAccessiscience_Cury_2019.pdf.jpg22-Nov-2019Structural basis of colchicine-site targeting acylhydrazones active against multidrug-resistant acute lymphoblastic leukemiaCury, Nathália Moreno; Mühlethaler, Tobias; Laranjeira, Angelo Brunelli Albertoni; Canevarolo, Rafael Renatino; Zenatti, Priscila Pini; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Song, Chunhua; Sun,Dongxiao; Dovat, Sinisa; Yunes, Rosendo Augusto; Prota, Andrea E.; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID ; Yunes, José Andrésartículo
18openAccesselife_prota_2023.pdf.jpg6-Mar-2023Structural insight into the stabilization of microtubules by taxanesProta, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Ma, Yuntao; Estévez-Gallego, Juan CSIC ORCID ; Li, Shuo; Bargsten, Katja; Josa-Prado, Fernando CSIC ORCID; Altmann, Karl-Heinz; Gaillard, Natacha; Kamimura, Shinji; Mühlethaler, Tobias; Gago, Federico CSIC ORCID; Oliva, María A. CSIC ORCID ; Steinmetz, Michel O.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID artículo
19openAccesselife-Estévez-Gallego-2020.pdf.jpg10-Mar-2020Structural model for differential cap maturation at growing microtubule endsEstévez-Gallego, Juan CSIC ORCID ; Josa-Prado, Fernando CSIC ORCID; Ku, Siou; Martínez Buey, Rubén CSIC ORCID CVN; Balaguer, Francisco de Asís CSIC ORCID; Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Kamma-Lorger, C.S.; Yagi, Toshiki; Iwamoto, Hiroyuki; Duchesne, Laurence; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Chrétien, Denis; Kamimura, Shinji; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID artículo
20closedAccessaccesoRestringido.pdf.jpg15-Jan-2019Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agentsBrindisi, Margherita; Ulivieri, Cristina; Alfano, Gloria; Gemma, Sandra; Balaguer, Francisco de Asís CSIC ORCID; Khan, Tuhina; Grillo, Alessandro; Chemi, Giulia; Menchon, Grégory; Prota, Andrea E.; Olieric, Natacha; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Nebbioso, Angela; Conte, Mariarosaria; Lopresti, Ludovica; Magnano, Stefania; Amet, Rebecca; Kinsella, Paula; Zisterer, Daniela M.; Ibrahim, Ola; O'Sullivan, Jeff; Morbidelli, Lucia; Spaccapelo, Roberta; Baldari, Cosima T.; Butini, Stefania; Novellino, Ettore; Campiani, Giuseppe; Altucci, Lucia; Steinmetz, Michel O.; Brogi, Simoneartículo