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openAccessSaizM_AWideRangingAntiviral.pdf.jpg4-ago-2020A wide-ranging antiviral response in wild boar cells is triggered by non-coding synthetic rnas from the foot-and-mouth disease virus genomeRodríguez Pulido, Miguel Ramón CSIC ORCID; Ranjitha, H.B.; Sáiz, Margarita CSIC ORCIDartículo
closedAccess2017Combined administration of synthetic RNA and a conventional vaccine improves immune responses and protection against foot-and-mouth disease virus in swineBorrego, Belén CSIC ORCID; Blanco Lavilla, Esther CSIC ORCID; Rodríguez Pulido, Miguel Ramón CSIC ORCID; Mateos, Francisco; Lorenzo, Gema CSIC ORCID ; Cardillo, S.; Smitsaart, E.; Sobrino Castelló, Francisco CSIC ORCID; Sáiz, Margarita CSIC ORCIDartículo
openAccessSáizM_DeliveryOfSynthetic.pdf.jpg2013Delivery of synthetic RNA can enhance the immunogenicity of vaccines against foot-and-mouth disease virus (FMDV) in miceBorrego, Belén CSIC ORCID; Rodríguez Pulido, Miguel Ramón CSIC ORCID; Mateos, Francisco; Losa, Nuria de la; Sobrino Castelló, Francisco CSIC ORCID; Sáiz, Margarita CSIC ORCIDartículo
openAccessimmunogenic_peptide-based_multiepitopic_vaccines.pdf.jpg22-jul-2020Designing functionally versatile, highly immunogenic peptide-based multiepitopic vaccines against foot-and-mouth disease VirusDefaus, Sira; Forner, Mar; Cañas-Arranz, Rodrigo; León, Patricia de CSIC ORCID; Bustos, Maria José; Rodríguez Pulido, Miguel Ramón CSIC ORCID; Blanco Lavilla, Esther CSIC ORCID; Sobrino Castelló, Francisco CSIC ORCID; Andreu, David
openAccessSobrinoF_DesigningFunctionally.pdf.jpg22-jul-2020Designing functionally versatile, highly immunogenic peptide-based multiepitopic vaccines against foot-and-mouth disease virusDefaus, Sira; Rodríguez Pulido, Miguel Ramón CSIC ORCID; Sobrino Castelló, Francisco CSIC ORCID; Bustos, Maria José; León, Patricia de CSIC ORCID; Cañas-Arranz, Rodrigo; Forner, Mar; Blanco Lavilla, Esther CSIC ORCID; Andreu, Davidartículo
closedAccessoficial.pdf.jpg2007Foot-and-mouth disease virus infection induces proteolytic cleavage of PTB, eIF3a,b, and PABP RNA-binding proteinsRodríguez Pulido, Miguel Ramón CSIC ORCID; Serrano, Paula CSIC; Sáiz, Margarita CSIC ORCID; Martínez-Salas, E.artículo
openAccessSáizM_InnateImmuneSensor.pdf.jpg29-jun-2018Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virusRodríguez Pulido, Miguel Ramón CSIC ORCID; Sánchez-Aparicio, María T.; Martínez-Salas, Encarnación CSIC ORCID; García-Sastre, Adolfo; Sobrino Castelló, Francisco CSIC ORCID; Sáiz, Margarita CSIC ORCIDartículo
closedAccess2011Inoculation of newborn mice with non-coding regions of foot-and-mouth disease virus RNA can induce a rapid, solid and wide-range protection against viral infectionRodríguez Pulido, Miguel Ramón CSIC ORCID; Sobrino Castelló, Francisco CSIC ORCID; Borrego, Belén CSIC ORCID; Sáiz, Margarita CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2012Modulation of foot-and-mouth disease virus pH threshold for uncoating correlates with differential sensitivity to inhibition of cellular Rab GTPases and decreases infectivity in vivoVázquez-Calvo, Ángela CSIC ORCID; Caridi, Flavia CSIC ORCID; Rodríguez Pulido, Miguel Ramón CSIC ORCID; Borrego, Belén CSIC ORCID; Sáiz, Margarita CSIC ORCID; Sobrino Castelló, Francisco CSIC ORCID; Martín-Acebes, M. A.artículo
openAccessSaizM_MolecularMechanismOfFootAndMouthDisease.pdf.jpg13-jun-2017Molecular mechanisms of foot-and-mouth disease virus targeting the host antiviral responseRodríguez Pulido, Miguel Ramón CSIC ORCID; Sáiz, Margarita CSIC ORCIDartículo
openAccessF_Sobrino_Mutations.pdf.jpg2012Mutations that hamper dimerization of foot-and-mouth disease virus 3A protein are detrimental for infectivityGonzález-Magaldi, Mónica CSIC ORCID; Postigo, Raúl CSIC; Vieira, Yuri A. CSIC; Rodríguez Pulido, Miguel Ramón CSIC ORCID; López-Viñas, Eduardo; Gómez-Puertas, Paulino CSIC ORCID ; Rosas, María Flora CSIC; Sobrino Castelló, Francisco CSIC ORCIDartículo
openAccessNon_coding_RNAs_derived_from.pdf.jpg29-mar-2023Non-coding RNAs derived from the foot-and-mouth disease virus genome trigger broad antiviral activity against coronavirusesRodríguez Pulido, Miguel Ramón CSIC ORCID; Calvo Pinilla, Eva María; Polo, Miryam; Saiz Calahorra, Juan Carlos; Fernández González, Raúl; Pericuesta Camacho, Eva; Gutiérrez-Adán, Alfonso CSIC ORCID ; Sobrino Castelló, Francisco CSIC ORCID; Martín-Acebes, M. A.; Sáiz, Margarita CSIC ORCIDartículo
openAccessSobrinoF_Peptide-BasedVaccines.pdf.jpg8-may-2021Peptide-Based Vaccines: Foot-and-Mouth Disease Virus, a Paradigm in Animal HealthForner, Mar; Cañas-Arranz, Rodrigo; Defaus, Sira; León, Patricia de CSIC ORCID; Rodríguez Pulido, Miguel Ramón CSIC ORCID; Ganges, Llilianne; Blanco Lavilla, Esther CSIC ORCID; Sobrino Castelló, Francisco CSIC ORCID; Andreu, Davidartículo de revisión
closedAccess2014Protection against Rift Valley fever virus infection in mice upon administration of interferon-inducing RNA transcripts from the FMDV genomeLorenzo, Gema CSIC ORCID ; Rodríguez Pulido, Miguel Ramón CSIC ORCID; López-Gil, E.; Sobrino Castelló, Francisco CSIC ORCID; Borrego, Belén CSIC ORCID; Sáiz, Margarita CSIC ORCID; Brun Torres, Alejandroartículo
openAccessFrancisco_Sobrino_Protection.pdf.jpg2012Protection against West Nile Virus Infection in Mice after Inoculation with Type I Interferon-Inducing RNA TranscriptsRodríguez Pulido, Miguel Ramón CSIC ORCID; Martín-Acebes, M. A.; Escribano-Romero, Estela; Blázquez, Ana B.; Sobrino Castelló, Francisco CSIC ORCID; Borrego, Belén CSIC ORCID; Sáiz, Margarita CSIC ORCID; Saiz Calahorra, Juan Carlosartículo
closedAccess2011RNA structural domains in noncoding regions of the foot-and-mouth disease virus genome trigger innate immunity in porcine cells and miceRodríguez Pulido, Miguel Ramón CSIC ORCID; Borrego, Belén CSIC ORCID; Sobrino Castelló, Francisco CSIC ORCID; Sáiz, Margarita CSIC ORCIDartículo
openAccessSáizM_SyntheticRNAs.pdf.jpg17-jul-2015Synthetic RNAs mimicking structural domains in the foot-and-mouth disease virus genome elicit a broad innate immune response in porcine cells triggered by RIG-I and TLR activationBorrego, Belén CSIC ORCID; Rodríguez Pulido, Miguel Ramón CSIC ORCID; Revilla, Concepción; Álvarez, Belén; Sobrino Castelló, Francisco CSIC ORCID; Domínguez, Javier; Sáiz, Margarita CSIC ORCIDartículo
openAccessWO2012131134A1.pdf.jpg4-oct-2012Use of a non-coding reglon of the genome of the foot-and-mouth virus for the purpose of producing an antiviral drugSáiz, Margarita CSIC ORCID; Sobrino Castelló, Francisco CSIC ORCID; Borrego, Belén CSIC ORCID; Rodríguez Pulido, Miguel Ramón CSIC ORCID; Saiz Calahorra, Juan Carlos; Martín-Acebes, M. A.patente
closedAccessFICHERO COMODÍN.pdf.jpg3-feb-2022Use of Foot-and-Mouth Disease Virus Non-coding Synthetic RNAs as Vaccine AdjuvantsRodríguez Pulido, Miguel Ramón CSIC ORCID; Polo, Miryam; Borrego, Belén CSIC ORCID; Sáiz, Margarita CSIC ORCIDcapítulo de libro
openAccessSáizM_UseRNADomains.pdf.jpg20-nov-2013Use of RNA Domains in the Viral Genome as Innate Immunity Inducers for Antiviral Strategies and Vaccine ImprovementRodríguez Pulido, Miguel Ramón CSIC ORCID; Sobrino Castelló, Francisco CSIC ORCID; Borrego, Belén CSIC ORCID; Sáiz, Margarita CSIC ORCIDcapítulo de libro