English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/171018
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Meta-analysis of the effects of foods and derived products containing ellagitannins and anthocyanins on cardiometabolic biomarkers: Analysis of factors influencing variability of the individual responses

AuthorsGarcía-Conesa, María Teresa ; Chambers, Karen; Combet, Emilie; Pinto, Paula; Garcia-Aloy, Mar; Andrés-Lacueva, Cristina; Pascual-Teresa, Sonia de ; Mena, Pedro; Konic Ristic, Aleksandra; Hollands, Wendy J.; Kroon, Paul A.; Rodríguez-Mateos, Ana; Istas, Geoffrey; Kontogiorgis, Christos A.; Rai, Dilip K.; Gibney, Eileen R.; Morand, Christine; Espín de Gea, Juan Carlos ; González-Sarrías, Antonio
KeywordsMeta-analysis
Ellagitannins
Anthocyanins
Interindividual variability
Cardiometabolic disorders
Pomegranate
Nuts
Berries
Red wine
Red grapes
Issue Date2018
PublisherMolecular Diversity Preservation International
CitationInternational Journal of Molecular Sciences 19(3): E694 (2018)
AbstractUnderstanding interindividual variability in response to dietary polyphenols remains essential to elucidate their effects on cardiometabolic disease development. A meta-analysis of 128 randomized clinical trials was conducted to investigate the effects of berries and red grapes/wine as sources of anthocyanins and of nuts and pomegranate as sources of ellagitannins on a range of cardiometabolic risk biomarkers. The potential influence of various demographic and lifestyle factors on the variability in the response to these products were explored. Both anthocyanin- and ellagitannin-containing products reduced total-cholesterol with nuts and berries yielding more significant effects than pomegranate and grapes. Blood pressure was significantly reduced by the two main sources of anthocyanins, berries and red grapes/wine, whereas waist circumference, LDL-cholesterol, triglycerides, and glucose were most significantly lowered by the ellagitannin-products, particularly nuts. Additionally, we found an indication of a small increase in HDL-cholesterol most significant with nuts and, in flow-mediated dilation by nuts and berries. Most of these effects were detected in obese/overweight people but we found limited or non-evidence in normoweight individuals or of the influence of sex or smoking status. The effects of other factors, i.e., habitual diet, health status or country where the study was conducted, were inconsistent and require further investigation.
Publisher version (URL)https://doi.org/10.3390/ijms19030694
URIhttp://hdl.handle.net/10261/171018
Identifiersdoi: 10.3390/ijms19030694
e-issn: 1422-0067
issn: 1661-6596
Appears in Collections:(ICTAN) Artículos
(CEBAS) Artículos
Files in This Item:
File Description SizeFormat 
metanalrespo.pdf710,25 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.