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Título: | The iroquois homeodomain proteins are required to specify body wall identity in Drosophila |
Autor: | Díez del Corral, Ruth CSIC ORCID; Aroca, Pilar; Gómez-Skarmeta, José Luis CSIC ORCID ; Cavodeassi, Florencia CSIC ORCID; Modolell, Juan CSIC | Palabras clave: | Iroquois complex Imaginal wing disc Thorax development Drosophila |
Fecha de publicación: | 1999 | Editor: | Cold Spring Harbor Laboratory Press | Citación: | Genes and Development 13(13): 1754-1761 (1999) | Resumen: | The Iroquois complex (Iro-C) homeodomain proteins allow cells at the proximal part of the Drosophila imaginal wing disc to form mesothoracic body wall (notum). Cells lacking these proteins form wing hinge structures instead (tegula and axillary sclerites). Moreover, the mutant cells impose on neighboring wild-type cells more distal developmental fates, like lateral notum or wing hinge. These findings support a tergal phylogenetic origin for the most proximal part of the wing and provide evidence for a novel pattern organizing center at the border between the apposed notum (Iro-C-expressing) and hinge (Iro-C-nonexpressing) cells. This border is not a cell lineage restriction boundary. | Versión del editor: | https://doi.org/10.1101/gad.13.13.1754 | URI: | http://hdl.handle.net/10261/198428 | DOI: | 10.1101/gad.13.13.1754 | Identificadores: | doi: 10.1101/gad.13.13.1754 issn: 0890-9369 e-issn: 1549-5477 |
Aparece en las colecciones: | (CABD) Artículos (CBM) Artículos |
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iroquiosiden.pdf | 3,86 MB | Adobe PDF | Visualizar/Abrir |
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