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Gajate, Consuelo

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Firma en Digital.CSIC (*)
Gajate, Consuelo
 
Centro o Instituto
CSIC - Centro de Investigaciones Biologicas Margarita Salas (CIB)
 
Departamento
Biomedicina Molecular
 
Especialización
Apoptosis; antitumor drugs; mechanism of action; pancreatic cancer; cancer stem cells
 
Email
cgajate@cib.csic.es
 
ORCID
 
Perfil en Google Scholar
 
Scopus AuthorID
 
Otros - ResearchGate
 

Publications

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Autor:  Mollinedo, Faustino
Fulltext:  With Fulltext

Resultados 1-20 de 29.

DerechosPreviewFecha Public.TítuloAutor(es)Tipo
1openAccesssep-2016Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapyJaffrès, Paul-Alain; Gajate, Consuelo CSIC ORCID ; Bouchet, Ana Maria CSIC; Couthon-Gourvès, Hélène; Chantôme, Aurélie; Potier-Cartereau, Marie; Besson, Pierre; Bougnoux, Philippe; Mollinedo, Faustino CSIC ORCID ; Vandier, Christopheartículo
2openAccessBiomedicine and Pharmacoptherapy_Dakir_2023.pdf.jpgnov-2023Antitumor activity of alkylphospholipid edelfosine in prostate cancer models and endoplasmic reticulum targetingDakir, El Habib; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID artículo
3openAccess2011Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulumGajate, Consuelo CSIC ORCID ; Matos-da-Silva, Marcia CSIC; Dakir, El Habib; Fonteriz, Rosalba I. CSIC ORCID; Álvarez, Javier CSIC ORCID; Mollinedo, Faustino CSIC ORCID artículo
4openAccessPROAPOPTOTIC.pdf.jpg2002Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH3 (edelfosine), a proapoptotic agent in tumor cellsGajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID artículo
5openAccessbst_mollinedo_2022.pdf.jpg19-may-2022Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapyMollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID artículo
6openAccess2017 CEJ RAS.pdf.jpg2017Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic SignalingMarín-Ramos, Nagore I.; Piñar, Carmen; Vazquez-Villa, Henar; Martín-Fontecha, Mar; González, Ángel; Canales, Ángeles CSIC ORCID; Algar, S.; Mayo, Paloma P.; Jiménez-Barbero, Jesús CSIC ORCID; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Pardo, Leonardo; Ortega-Gutiérrez, S.; Viso, Alma CSIC ORCID ; López-Rodríguez, María L.artículo
7openAccesscytostatic_Gajate.pdf.jpg1-nov-2002Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells: Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosisGajate, Consuelo CSIC ORCID ; An, Feiyun; Mollinedo, Faustino CSIC ORCID artículo
8openAccesscancers_mollinedo_2021.pdf.jpg19-ago-2021Direct endoplasmic reticulum targeting by the selective alkylphospholipid analog and antitumor ether lipid edelfosine as a therapeutic approach in pancreatic cancerMollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID artículo
9openAccessDrug uptake.pdf.jpg2013Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeastCuesta-Marbán, Álvaro CSIC; Botet, Javier CSIC; Czyz, Ola; Cacharro, Luis M. CSIC; Gajate, Consuelo CSIC ORCID ; Hornillos, Valentín CSIC ORCID; Delgado, Javier; Zhang, Hui; Amat-Guerri, Francisco CSIC; Acuña, A. Ulises CSIC; McMaster, Christopher R.; Revuelta Doval, José Luis CSIC ORCID CVN; Zaremberg, Vanina; Mollinedo, Faustino CSIC ORCID artículo
10openAccessGajate_Mollinedo_Blood_2007.pdf.jpg2007Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid raftsGajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID artículo
11openAccessalkylphospholipid.pdf.jpg2015Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosineBonilla, Ximena; Dakir, El Habib; Mollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID artículo
12openAccessEdelfosine.pdf.jpg2010In vitro and in vivo selective antitumor activity of edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid raftsMollinedo, Faustino CSIC ORCID ; Iglesia-Vicente, Janis de la; Gajate, Consuelo CSIC ORCID ; Estella-Hermoso de Mendoza, A.; Villa-Pulgarín, J. A.; Roué, Gaël; Colomer, Dolors; Campanero, Miguel A.; Blanco-Prieto, María J.artículo
13openAccessInduction of Apoptosis_Gajate_PV_Art2021.pdf.jpg2021Induction of Apoptosis in Human Pancreatic Cancer Stem Cells by the Endoplasmic Reticulum-Targeted Alkylphospholipid Analog Edelfosine and Potentiation by Autophagy InhibitionGajate, Consuelo CSIC ORCID ; Gayet, Odile; Fraunhoffer, Nicolas A.; Iovanna, Juan Lucio; Dusetti, Nelson; Mollinedo, Faustino CSIC ORCID artículo
14openAccessGraphical abstract.pdf.jpg2-mar-2018Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cellsBello, Claudia; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Vogel, Pierreartículo
15openAccess353.pdf.jpg2-ago-2004Intracellular Triggering of Fas Aggregation and Recruitment of Apoptotic Molecules into Fas-enriched Rafts in Selective Tumor Cell ApoptosisGajate, Consuelo CSIC ORCID ; Canto-Jañez, Esther del; Acuña, A. Ulises CSIC; Amat-Guerri, Francisco CSIC; Geijo-Barrientos, Emilio CSIC ORCID; Santos-Beneit, Antonio M. CSIC; Veldman, Robert J.; Mollinedo, Faustino CSIC ORCID artículo
16openAccess19-may-2011Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondriaMollinedo, Faustino CSIC ORCID ; Hornillos, Valentín CSIC ORCID; Delgado, Javier; Amat-Guerri, Francisco CSIC; Acuña, A. Ulises CSIC; Nieto-Miguel, Teresa; Villa-Pulgarín, J. A.; Gajate, Consuelo CSIC ORCID artículo
17openAccessInvolvement of Raft.pdf.jpg2009Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cellsGajate, Consuelo CSIC ORCID ; González-Camacho, Fernando CSIC ORCID; Mollinedo, Faustino CSIC ORCID artículo
18openAccessLipid raft-mediated Akt.pdf.jpg2013Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphomaReis-Sobreiro, M.; Roué, Gaël; Moros, A.; Gajate, Consuelo CSIC ORCID ; Iglesia-Vicente, Janis de la; Colomer, Dolors; Mollinedo, Faustino CSIC ORCID artículo
19openAccesssep-2011Lipid rafts and fas/CD95 signaling in cancer chemotherapyMollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID artículo
20openAccessJournal of Lipid Research_Mollinedo_2020.pdf.jpg27-ene-2020Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapyMollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID artículo