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Rights | Preview | Issue Date | Title | Author(s) | Type |
closedAccess |  | 11-Jul-2019 | A potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor improves survival in ras-driven acute myeloid leukemia | Marín-Ramos, Nagore I.; Balabasquer, Moisés; Ortega-Nogales, Francisco J.; Torrecillas, I. R.; Gil-Ordóñez, Ana; Marcos-Ramiro, Beatriz; Aguilar-Garrido, Pedro; Cushman, Ian; Romero, Antonio CSIC ORCID ; Medrano, Francisco Javier CSIC ORCID ; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Philips, Mark R.; Campillo, M.; Gallardo, Miguel; Martín-Fontecha, Mar; López-Rodríguez, María L.; Ortega-Gutiérrez, S. | artículo |
openAccess | | Sep-2016 | Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy | Jaffrès, Paul-Alain; Gajate, Consuelo CSIC ORCID ; Bouchet, Ana Maria; Couthon-Gourvès, Hélène; Chantôme, Aurélie; Potier-Cartereau, Marie; Besson, Pierre; Bougnoux, Philippe; Mollinedo, Faustino CSIC ORCID ; Vandier, Christophe | artículo |
closedAccess |  | 2018 | Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active component | Conde-Rioll, María; Gajate, Consuelo CSIC ORCID ; Fernández, José J.; Villa-Pulgarín, J. A.; Napolitano, José G.; Norte, Manuel; Mollinedo, Faustino CSIC ORCID | artículo |
openAccess | | 2011 | Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum | Gajate, Consuelo CSIC ORCID ; Matos-da-Silva, Marcia CSIC; Dakir, El Habib; Fonteriz, Rosalba I. CSIC ORCID; Álvarez, Javier CSIC ORCID; Mollinedo, Faustino CSIC ORCID | artículo |
closedAccess |  | 2008 | Aplidin, a marine organism-derived compound with potent antimyeloma activity in vitro and in vivo | Mitsiades, C. S.; Ocio, Enrique M. CSIC ORCID ; Pandiella, Atanasio CSIC ORCID CVN ; Maiso, Patricia; Gajate, Consuelo CSIC ORCID ; Garayoa, Mercedes CSIC ORCID ; Vilanova, David; Montero, Juan Carlos CSIC ORCID; Mollinedo, Faustino CSIC ORCID ; San Miguel, Jesús F. CSIC ORCID | artículo |
closedAccess |  | 2012 | Apoptotic mechanisms are involved in the death of Strongyloides venezuelensis after triggering of nitric oxide | Ruano, A. L.; López-Abán, J.; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Melo, A. L. de; Muro, Antonio | artículo |
openAccess |  | 2002 | Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH3 (edelfosine), a proapoptotic agent in tumor cells | Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID | artículo |
openAccess |  | 19-May-2022 | Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy | Mollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID | artículo |
openAccess |  | 2017 | Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling | Marín-Ramos, Nagore I.; Piñar, Carmen; Vazquez-Villa, Henar; Martín-Fontecha, Mar; González, Ángel; Canales, Ángeles CSIC ORCID; Algar, S.; Mayo, Paloma P.; Jiménez-Barbero, Jesús CSIC ORCID; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Pardo, Leonardo; Ortega-Gutiérrez, S.; Viso, Alma CSIC ORCID; López-Rodríguez, María L. | artículo |
openAccess |  | 1-Nov-2002 | Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells: Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosis | Gajate, Consuelo CSIC ORCID ; An, Feiyun; Mollinedo, Faustino CSIC ORCID | artículo |
closedAccess |  | 2008 | Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cells | Mollinedo, Faustino CSIC ORCID ; López-Pérez, Ricardo CSIC ORCID CVN; Gajate, Consuelo CSIC ORCID | artículo |
closedAccess |  | 2006 | Differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cells | Nieto-Miguel, Teresa; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID | artículo |
openAccess |  | 19-Aug-2021 | Direct endoplasmic reticulum targeting by the selective alkylphospholipid analog and antitumor ether lipid edelfosine as a therapeutic approach in pancreatic cancer | Mollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID | artículo |
closedAccess |  | 2005 | DNA and non-DNA targets in the mechanism of action of the antitumor drug trabectedin | David-Cordonnier, Marie-Hélène; Gajate, Consuelo CSIC ORCID ; Iglesia-Vicente, Janis de la; Mollinedo, Faustino CSIC ORCID | artículo |
openAccess |  | 2013 | Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast | Cuesta-Marbán, Álvaro CSIC; Botet, Javier CSIC; Czyz, Ola; Cacharro, Luis M. CSIC; Gajate, Consuelo CSIC ORCID ; Hornillos, Valentín CSIC ORCID; Delgado, Javier; Zhang, Hui; Amat-Guerri, Francisco CSIC; Acuña, A. Ulises CSIC; McMaster, Christopher R.; Revuelta Doval, José Luis CSIC ORCID; Zaremberg, Vanina; Mollinedo, Faustino CSIC ORCID | artículo |
openAccess |  | 2007 | Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts | Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID | artículo |
closedAccess |  | 2006 | Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes | Torrecillas, Alejandro; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID | artículo |
closedAccess |  | 2007 | Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells | Nieto-Miguel, Teresa; Fonteriz, Rosalba I. CSIC ORCID; Vay, Laura CSIC; Gajate, Consuelo CSIC ORCID ; López-Hernández, Silvia; Mollinedo, Faustino CSIC ORCID | artículo |
openAccess |  | 2015 | Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosine | Bonilla, Ximena; Dakir, El Habib; Mollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID | artículo |
closedAccess |  | 2004 | ET-18-OCH3 (edelfosine): A selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor | Mollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID ; Martín-Santamaría, Sonsoles CSIC ORCID ; Gago, Federico CSIC ORCID | artículo |