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closedAccessrestringido.pdf.jpg11-Jul-2019A potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor improves survival in ras-driven acute myeloid leukemiaMarín-Ramos, Nagore I.; Balabasquer, Moisés; Ortega-Nogales, Francisco J.; Torrecillas, I. R.; Gil-Ordóñez, Ana; Marcos-Ramiro, Beatriz; Aguilar-Garrido, Pedro; Cushman, Ian; Romero, Antonio CSIC ORCID ; Medrano, Francisco Javier CSIC ORCID ; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Philips, Mark R.; Campillo, M.; Gallardo, Miguel; Martín-Fontecha, Mar; López-Rodríguez, María L.; Ortega-Gutiérrez, S.artículo
openAccessSep-2016Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapyJaffrès, Paul-Alain; Gajate, Consuelo CSIC ORCID ; Bouchet, Ana Maria; Couthon-Gourvès, Hélène; Chantôme, Aurélie; Potier-Cartereau, Marie; Besson, Pierre; Bougnoux, Philippe; Mollinedo, Faustino CSIC ORCID ; Vandier, Christopheartículo
closedAccessaccesoRestringido.pdf.jpg2018Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active componentConde-Rioll, María; Gajate, Consuelo CSIC ORCID ; Fernández, José J.; Villa-Pulgarín, J. A.; Napolitano, José G.; Norte, Manuel; Mollinedo, Faustino CSIC ORCID artículo
openAccess2011Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulumGajate, Consuelo CSIC ORCID ; Matos-da-Silva, Marcia; Dakir, El Habib; Fonteriz, Rosalba I. CSIC ORCID; Álvarez, Javier; Mollinedo, Faustino CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2008Aplidin, a marine organism-derived compound with potent antimyeloma activity in vitro and in vivoMitsiades, C. S.; Ocio, Enrique M. CSIC ORCID ; Pandiella, Atanasio CSIC ORCID CVN ; Maiso, Patricia; Gajate, Consuelo CSIC ORCID ; Garayoa, Mercedes CSIC ORCID ; Vilanova, David; Montero, Juan Carlos CSIC ORCID; Mollinedo, Faustino CSIC ORCID ; San Miguel, Jesús F. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2012Apoptotic mechanisms are involved in the death of Strongyloides venezuelensis after triggering of nitric oxideRuano, A. L.; López-Abán, J.; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Melo, A. L. de; Muro, Antonioartículo
openAccessPROAPOPTOTIC.pdf.jpg2002Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH3 (edelfosine), a proapoptotic agent in tumor cellsGajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID artículo
openAccesscytostatic_Gajate.pdf.jpg1-Nov-2002Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells: Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosisGajate, Consuelo CSIC ORCID ; An, Feiyun; Mollinedo, Faustino CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2008Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cellsMollinedo, Faustino CSIC ORCID ; López-Pérez, Ricardo CSIC ORCID CVN; Gajate, Consuelo CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2006Differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cellsNieto-Miguel, Teresa; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2005DNA and non-DNA targets in the mechanism of action of the antitumor drug trabectedinDavid-Cordonnier, Marie-Hélène; Gajate, Consuelo CSIC ORCID ; Iglesia-Vicente, Janis de la; Mollinedo, Faustino CSIC ORCID artículo
openAccessDrug uptake.pdf.jpg2013Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeastCuesta-Marbán, Álvaro CSIC; Botet, Javier CSIC; Czyz, Ola; Cacharro, Luis M. CSIC; Gajate, Consuelo CSIC ORCID ; Hornillos, Valentín CSIC ORCID; Delgado, Javier; Zhang, Hui; Amat-Guerri, Francisco CSIC; Acuña, A. Ulises CSIC; McMaster, Christopher R.; Revuelta Doval, José Luis CSIC ORCID; Zaremberg, Vanina; Mollinedo, Faustino CSIC ORCID artículo
openAccessGajate_Mollinedo_Blood_2007.pdf.jpg2007Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid raftsGajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2006Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranesTorrecillas, Alejandro; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2007Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cellsNieto-Miguel, Teresa; Fonteriz, Rosalba I. CSIC ORCID; Vay, Laura; Gajate, Consuelo CSIC ORCID ; López-Hernández, Silvia; Mollinedo, Faustino CSIC ORCID artículo
openAccessalkylphospholipid.pdf.jpg2015Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosineBonilla, Ximena; Dakir, El Habib; Mollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2004ET-18-OCH3 (edelfosine): A selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptorMollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID ; Martín-Santamaría, Sonsoles CSIC ORCID ; Gago, Federico CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2006Fas/CD95 death receptor and lipid rafts: New targets for apoptosis-directed cancer therapyMollinedo, Faustino CSIC ORCID ; Gajate, Consuelo CSIC ORCID artículo
closedAccess21-Sep-2004Fluorescent Phenylpolyene Analogues of the Ether Phospholipid Edelfosine for the Selective Labeling of Cancer CellsQuesada, Ernesto CSIC ORCID; Delgado, Javier; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Acuña, A. Ulises CSIC; Amat-Guerri, Francisco CSICartículo
closedAccessaccesoRestringido.pdf.jpg2005Further naphthylcombretastatins. An investigation on the role of the naphthalene moietyMaya, Ana B. S.; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID artículo