Synthesis and properties of Nα-lauroyl-L-arginine dipeptides from collagen-lauroyl-L-arginine dipeptides from collagen

Abstract

In order to obtain protein-based amphoteric surfactants with antimicrobial properties, N α -lauroyl arginine dipeptides have been prepared by condensation between N α -lauroyl arginine and amino acids which come from a collagen hydrolysate. Some surfactant properties and the minimum inhibitory concentration against Gram positive and Gram negative bacteria have been evaluated. All types of compounds presented a surfactant-like behavior. Furthermore, the compounds described in this paper may be considered as mild preservative or protective substances.