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Título: | Advances in diagnosis of gastrointestinal nematodes in livestock and companion animals |
Autor: | Rinaldi, L.; Krücken, J.; Martínez Valladares, María CSIC ORCID CVN ; Pepe, P.; Maurelli, M.P.; De Queiroz, C.; Castilla Gómez de Agüero, Verónica CSIC ORCID; Wang, T.; Cringoli, G.; Charlier, J.; Gilleard, J.S.; Von Samson Himmelstjerna, G. | Fecha de publicación: | 2022 | Editor: | Elsevier | Citación: | Advances in Parasitology 118: 85- 176 (2022) | Resumen: | Diagnosis of gastrointestinal nematodes in livestock and companion animals has been neglected for years and there has been an historical underinvestment in the develop- ment and improvement of diagnostic tools, undermining the undoubted utility of surveillance and control programmes. However, a new impetus by the scientific com- munity and the quickening pace of technological innovations, are promoting a renais- sance of interest in developing diagnostic capacity for nematode infections in veterinary parasitology. A cross-cutting priority for diagnostic tools is the development of pen-side tests and associated decision support tools that rapidly inform on the levels of infection and morbidity. This includes development of scalable, parasite detection using artificial intelligence for automated counting of parasitic elements and research towards esta- blishing biomarkers using innovative molecular and proteomic methods. The aim of this review is to assess the state-of-the-art in the diagnosis of helminth infections in livestock and companion animals and presents the current advances of diagnostic methods for intestinal parasites harnessing (i) automated methods for copromicroscopy based on artificial intelligence, (ii) immunodiagnosis, and (iii) molecular- and proteome-based approaches. Regardless of the method used, multiple factors need to be considered before diagnostics test results can be interpreted in terms of control decisions. Guidelines on how to apply diagnostics and how to interpret test results in different animal species are increasingly requested and some were recently made available in veterinary parasitology for the different domestic species. | Descripción: | 92 páginas, 3 tablas, 4 figuras. | Versión del editor: | http://dx.doi.org/10.1016/BS.APAR.2022.07.002 | URI: | http://hdl.handle.net/10261/303426 | DOI: | 10.1016/BS.APAR.2022.07.002 | Identificadores: | doi: 10.1016/BS.APAR.2022.07.002 issn: 0065-308X |
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