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Open Access item High sequence variability of myticin transcripts in hemocytes of immune-stimulated mussels suggests ancient host-pathogen interactions

Authors:Pallavicini, Alberto
Costa, M. M.
Gestal, C.
Dréos, René
Figueras, Antonio
Venier, Paola
Keywords:Mytilus, Myticin, Mussel, Antimicrobial
Issue Date:2008
Citation:Developmental and Comparative Immunology 32(3): 213-226 (2008)
Abstract:Small cationic antimicrobial peptides (AMPS) are host defense molecules detected in virtually all gropus of organisms. To investigate the immuine response mechanisms of Mytilus galloprovincialis, primary and suppresion subtractive hybridization libraries were prepared from hemolymph of mussels injected with heat-inactivated bacteria or ply l:C, the latter mimicking viral infection. After DNA sequencing, sequence processing and similarity searching, a remarkable abundance of AMP mRNAS were identified.
Publisher version (URL):http://dx.doi.org/10.1016/j.dci.2007.05.008
Appears in Collections:(IIM) Artículos

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