Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/289334
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Profiling cellular diversity in sponges informs animal cell type and nervous system evolution |
Autor: | Hernández-Plaza, Ana; Musser, Jacob M.; Schippers, Klaske J.; Nickel, Michael; Mizzon, Giulia; Kohn, Andrea B.; Pape, Constantin; Ronchi, Paolo; Papadopoulos, Nikolaos; Tarashansky, Alexander J.; Hammel, Jörg U.; Wolf, Florian; Liang, Cong; Cantalapiedra, Carlos P; Achim, Kaia; Schieber, Nicole L.; Pan, Leslie; Ruperti, Fabian; Francis, Warren R.; Vargas, Sergio; Kling, Svenja; Renkert, Maike; Polikarpov, Maxim; Bourenkov, Gleb; Feuda, Roberto; Gaspar, Imre; Burkhardt, Pawel; Wang, Bo; Bork, Peer; Beck, Martin; Schneider, Thomas R.; Kreshuk, Anna; Wörheide, Gert; Huerta-Cepas, Jaime; Moroz, Leonid L.; Arendt, Detlev | Palabras clave: | Tethya-wilhelma SEQ data Gene Expression Genome Contraction Annotation Contrast Protein Water |
Fecha de publicación: | 5-nov-2021 | Editor: | American Association for the Advancement of Science | Citación: | Science 374: 717-723 (2021) | Resumen: | The evolutionary origin of metazoan cell types such as neurons and muscles is not known. Using whole-body single-cell RNA sequencing in a sponge, an animal without nervous system and musculature, we identified 18 distinct cell types. These include nitric oxide-sensitive contractile pinacocytes, amoeboid phagocytes, and secretory neuroid cells that reside in close contact with digestive choanocytes that express scaffolding and receptor proteins. Visualizing neuroid cells by correlative x-ray and electron microscopy revealed secretory vesicles and cellular projections enwrapping choanocyte microvilli and cilia. Our data show a communication system that is organized around sponge digestive chambers, using conserved modules that became incorporated into the pre- and postsynapse in the nervous systems of other animals. | URI: | http://hdl.handle.net/10261/289334 | DOI: | 10.1126/science.abj2949 | ISSN: | 0036-8075 | E-ISSN: | 1095-9203 |
Aparece en las colecciones: | (INIA) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Profiling cellular diversity in sponges informs animal cell type and nervous system evolution.pdf | 2,04 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
81
checked on 09-abr-2024
WEB OF SCIENCETM
Citations
76
checked on 11-feb-2024
Page view(s)
60
checked on 03-may-2024
Download(s)
304
checked on 03-may-2024
Google ScholarTM
Check
Altmetric
Altmetric
Este item está licenciado bajo una Licencia Creative Commons