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http://hdl.handle.net/10261/173159
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dc.contributor.author | Esteban-Tejeda, Leticia | - |
dc.contributor.author | Cabal, Belén | - |
dc.contributor.author | Torrecillas, Ramón | - |
dc.contributor.author | Prado, Catuxa | - |
dc.contributor.author | Fernández-García, Elisa | - |
dc.contributor.author | López-Píriz, Roberto | - |
dc.contributor.author | Quintero, Félix | - |
dc.contributor.author | Pou, Juan | - |
dc.contributor.author | Penide, J. | - |
dc.contributor.author | Moya, J. S. | - |
dc.date.accessioned | 2018-12-13T10:51:09Z | - |
dc.date.available | 2018-12-13T10:51:09Z | - |
dc.date.issued | 2016 | - |
dc.identifier | doi: 10.1088/1748-6041/11/4/045014 | - |
dc.identifier | e-issn: 1748-605X | - |
dc.identifier | issn: 1748-6041 | - |
dc.identifier.citation | Biomedical Materials 11(4): 045014 (2016) | - |
dc.identifier.uri | http://hdl.handle.net/10261/173159 | - |
dc.description.abstract | Two types of antimicrobial glass fibers containing ZnO and CaO, with diameters ranging from tens of nanometers to 1 m, were successfully fabricated by a laser spinning technique. The antimicrobial performance was corroborated according to ISO 20743:2013, by using gram-negative (Escherichia coli) and gram-positive (Streptococcus oralis, Streptococcus mutans and Staphylococcus aureus) bacteria, and yeast (Candida krusei) (more than 3 logs of reduction). The metabolic activity and endosomal system of eukaryotic cells were not altered by using eluents of CaO glass submicrometric fibers and ZnO fibers at 1 : 10 dilution as cellular media (viability rates over 70%). A dental material was functionalized by embedding ZnO nanofibers above the percolation threshold (20% wt), creating a three-dimensional (3D) fiber network that added an antimicrobial profile. This new ZnO glass fiber composite is proved non-cytotoxic and preserved the antimicrobial effect after immersion in human saliva. This is the first time that a fiber-reinforced liner with strong antimicrobial-activity has been created to prevent secondary caries. The potential of developing new fiber-reinforced composites (FRCs) with antimicrobial properties opens up an extensive field of dental applications where most important diseases have an infectious origin. | - |
dc.publisher | Institute of Physics Publishing | - |
dc.rights | closedAccess | - |
dc.title | Antimicrobial activity of submicron glass fibres incorporated as a filler to a dental sealer | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1088/1748-6041/11/4/045014 | - |
dc.date.updated | 2018-12-13T10:51:09Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | eng | - |
dc.relation.csic | Sí | - |
dc.identifier.pmid | 27509353 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.openairetype | artículo | - |
item.fulltext | No Fulltext | - |
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accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
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