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Título

Optimization of nano-emulsions prepared by low-energy emulsification methods at constant temperature using a factorial design study

AutorPey, Carmen M.; Maestro, Alicia; Solé, Isabel CSIC; González Azón, Carmen; Solans, Conxita CSIC ORCID ; Gutiérrez, José M. CSIC ORCID
Palabras claveNano-emulsions
Emulsification method
O/W emulsion
Full factorial design
Response surface methodology
Fecha de publicación6-mar-2006
EditorElsevier
CitaciónColloids and Surfaces A: Physicochemical and Engineering Aspects 288(1-3): 144-150 (2006)
ResumenThe aim of this work is the study and optimization of composition and preparation method of nano-emulsions O/W by addition of one of the components at constant temperature. Experimental design techniques have been used to carry out this study. A factorial design has been done in order to investigate the effect of formulation and preparation variables over emulsion properties. The conclusion of this study is that emulsion droplet size and polydispersity change with composition and preparation method. These variables have been optimized using a central composite design obtaining response surfaces that describe this preparation method of nano-emulsions.
Descripción7 pages, 6 figures, 5 tables.-- Printed version published Oct 5, 2006.-- Issue title: Papers from "Formula IV: Frontiers in Formulation Science", an International conference organised by the RSC, held in London, July 4-7th 2005.
Versión del editorhttp://dx.doi.org/10.1016/j.colsurfa.2006.02.026
URIhttp://hdl.handle.net/10261/12632
DOI10.1016/j.colsurfa.2006.02.026
ISSN0927-7757
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