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http://hdl.handle.net/10261/122918
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Sánchez, Diego | es_ES |
dc.contributor.author | Ganfornina, M. D. | es_ES |
dc.contributor.author | Bastiani, Michael J. | es_ES |
dc.date.accessioned | 2015-10-01T12:18:16Z | - |
dc.date.available | 2015-10-01T12:18:16Z | - |
dc.date.issued | 1995 | - |
dc.identifier.citation | Development 121(1): 135-147 (1995) | es_ES |
dc.identifier.issn | 0950-1991 | - |
dc.identifier.uri | http://hdl.handle.net/10261/122918 | - |
dc.description.abstract | This article describes the expression pattern and functional analysis of Lazarillo, a novel cell surface glycoprotein expressed in the embryonic grasshopper nervous system, and a member of the lipocalin family. Lazarillo is expressed by a subset of neuroblasts, ganglion mother cells and neurons of the central nervous system, by all sensory neurons of the peripheral nervous system, and by a subset of neurons of the enteric nervous system. It is also present in a few non neuronal cells associated mainly with the excretory system. A monoclonal antibody raised against Lazarillo perturbs the extent and direction of growth of identified commissural pioneer neurons. We propose that Lazarillo is the receptor for a midline morphogen involved in the outgrowth and guidance of these neurons. | es_ES |
dc.description.sponsorship | This work was supported by NIH grant to M. J. B. (NS25387). M. D. G. holds a fellowship from the Fulbright/MEC of Spain, and D. S. is the recipient of a NIH postdoctoral fellowship (1F05TW04686-01) | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Company of Biologists | es_ES |
dc.rights | closedAccess | es_ES |
dc.subject | Axon guidance | es_ES |
dc.subject | Lipocalin | es_ES |
dc.subject | Grasshopper | es_ES |
dc.subject | Lipid binding proteins | es_ES |
dc.title | Developmental expression of the lipocalin Lazarillo and its role in axonal pathfinding in the grasshopper embryo | es_ES |
dc.type | artículo | es_ES |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.identifier.e-issn | 1477-9129 | - |
dc.contributor.funder | National Institutes of Health (US) | es_ES |
dc.contributor.funder | Ministerio de Educación y Ciencia (España) | es_ES |
dc.relation.csic | No | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/100000002 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
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