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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
openAccess18F-choline.pdf.jpgmar-200618F-choline images murine atherosclerotic plaques ex vivoMatter, Christian M.; Wyss, Matthias T.; Meier, Patricia; Lohmann, Christine; Weber, Bruno; Ramírez de Molina, Ana CSIC ORCID; Ametamey, Simon M.; Lacal, Juan Carlos CSIC ORCID; Kaufmann, Philipp A.; Buck, Alfredartículo
closedAccessaccesoRestringido.pdf.jpg2012Acid ceramidase as a chemotherapeutic target to overcome resistance to the antitumoral effect of choline kinase α inhibitionRamírez de Molina, Ana CSIC ORCID; Cueva, Ana de la CSIC; Machado-Pinilla, R. CSIC; Rodriguez-Fanjul, V. CSIC ORCID; Gómez del Pulgar, Teresa CSIC; Cebrián, Arancha CSIC ORCID; Perona Abellón, Rosario CSIC ORCID; Lacal, Juan Carlos CSIC ORCIDartículo
openAccesskinases in Xenopus.pdf.jpgfeb-1995Activation of intracellular kinases in Xenopus oocytes by p21ras and phospholipases: a comparative studyCarnero, Amancio CSIC ORCID; Lacal, Juan Carlos CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg1-mar-1997Activation of phospholipase D by growth factors and oncogenes in murine fibroblasts follow alternative but cross-talking pathwaysPeso, Luis del CSIC ORCID; Lucas, Luisa CSIC; Esteve, Pilar CSIC ORCID ; Lacal, Juan Carlos CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg1999Activation of serum response factor by RhoA is mediated by the nuclear factor-κB and C/EBP transcription factorsMontaner, Silvia CSIC; Perona Abellón, Rosario CSIC ORCID; Saniger, Luisa; Lacal, Juan Carlos CSIC ORCIDartículo
openAccessWO2007138143A2.pdf.jpg6-dic-2007Alpha anticholine kinase monoclonal antibodies and their use in analytical techniques for the diagnosis of cancer and the preparation of medicinal productsRamírez de Molina, Ana CSIC ORCID; Gallego Ortega, David CSIC ORCID; Lacal, Juan Carlos CSIC ORCIDpatente
openAccessApoptosis induced.pdf.jpgdic-2000Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides productionEmbade, Nieves CSIC ORCID; Valerón, Pilar F.; Aznar, Salvador CSIC ORCID; López-Collazo, Eduardo CSIC; Lacal, Juan Carlos CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2011Approaches for the study of cancer: towards the integration of genomics, proteomics and metabolomicsCasado-Vela, Juan CSIC ORCID CVN; Cebrián, Arancha CSIC ORCID; Gómez del Pulgar, Teresa CSIC; Lacal, Juan Carlos CSIC ORCIDartículo
openAccess2933.pdf.jpgago-2002Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viabilitySánchez-Pérez, Isabel CSIC ORCID; Aznar, Salvador CSIC ORCID; Martínez-Gomariz, Montserrat; Lacal, Juan Carlos CSIC ORCID; Perona Abellón, Rosario CSIC ORCIDartículo
openAccessChanging the course of oncogenesis.pdf.jpg2006Changing the course of oncogenesis: The development of tyrosine kinase inhibitorsLacal, Juan Carlos CSIC ORCIDartículo
closedAccessdic-2008Choline kinase alpha depletion selectively kills tumoral cellsBáñez Coronel, Mónica CSIC; Ramírez de Molina, Ana CSIC ORCID; Rodríguez-González, Agustín; Sarmentero, Jacinto; Ramos, Mª Angeles; García Cabezas, Miguel Ángel; Garcia-Oroz, Lourdes; Lacal, Juan Carlos CSIC ORCIDartículo
openAccesscddis2013. T. Zimmerman.pdf.jpg28-nov-2013Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cellsSánchez-López, E.; Zimmerman, T. CSIC; Gómez del Pulgar, Teresa CSIC; Moyer, M.P.; Lacal, Juan Carlos CSIC ORCID; Cebrián, Arancha CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2004Choline kinase inhibition induces the increase in ceramides resulting in a highly specific and selective cytotoxic antitumoral strategy as a potential mechanism of actionRodríguez-González, Agustín; Ramírez de Molina, Ana CSIC ORCID; Fernández, Félix; Lacal, Juan Carlos CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2005Choline kinase is a novel oncogene that potentiates RhoA-induced carcinogenesisRamírez de Molina, Ana CSIC ORCID; Gallego Ortega, David CSIC ORCID; Sarmentero Estrada, Jacinto CSIC; Báñez Coronel, Mónica CSIC; Martín, Yolanda; Lacal, Juan Carlos CSIC ORCIDartículo
openAccessCholine Kinase_Lacal_PV_Art2022.pdf.jpg2022Choline kinase α inhibitors MN58b and RSM932A enhances the antitumor response to cisplatin in lung tumor cellsLacal, Juan Carlos CSIC ORCID; Perona Abellón, Rosario CSIC ORCID; Castro, Javier de; Cebrián, Arancha CSIC ORCIDartículo
openAccessCholine_Kinase_Lacal_PV_Art2021.pdf.jpg2021Choline kinase: An unexpected journey for a precision medicine strategy in human diseasesLacal, Juan Carlos CSIC ORCID; Zimmerman, Tahl; Campos, Joaquín M.artículo de revisión
openAccessMouse Xenografts.pdf.jpg2013Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: Evidence in human tumor-derived cell lines and mouse xenograftsCueva, Ana de la CSIC; Ramírez de Molina, Ana CSIC ORCID; Álvarez-Ayerza, Néstor CSIC; Ramos, Maria Angeles CSIC; Cebrián, Arancha CSIC ORCID; Gómez del Pulgar, Teresa CSIC; Lacal, Juan Carlos CSIC ORCIDartículo
openAccessWO2015028662_A1.pdf.jpg5-mar-2015Compositions and methods for characterization and amelioration of rheumatoid arthritisFirestein, Gary S.; Guma, Mónica; Karin, Michael; Sánchez-López, Elsa CSIC ORCID CVN; Lacal, Juan Carlos CSIC ORCID; Tiziani, Stefanopatente
openAccess2277568_B1.pdf.jpg1-abr-2008Derivados de triterpenoquinonas y triterpenofenoles y su aplicación para el tratamiento de tumores y enfermedades parasitariasLacal, Juan Carlos CSIC ORCID; Ramírez de Molina, Ana CSIC ORCID; Báñez Coronel, Mónica CSIC; Gutiérrez Ravelo, Ángel; Estévez-Braun, Ana; Mesa Siverio, Dulce Y.; Pérez Sacau, Elisapatente
openAccessEP1710236A1-1.pdf.jpg15-abr-2010Derivatives of pyridine and quinolineLacal, Juan Carlos CSIC ORCID; Campos Rosa, Joaquín M.; Gallo Meza, Miguel Angel; Espinosa Ubeda, Antoniosolicitud de patente