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closedAccessaccesoRestringido.pdf.jpg12-oct-2020A method for the stereoselective construction of the hemiaminal center in zampanolidesBrütsch, Tobias M.; Berardozzi, Simone; Rothe, Marlene L.; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinzartículo
closedAccess1-abr-2011Acetylation of hydroxytyrosol enhances its transport across differentiated Caco-2 cell monolayersMateos, Raquel CSIC ORCID ; Pereira-Caro, Gema; Saha, Shikha; Cert, María Rosa CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Bravo, Laura CSIC ORCID; Kroon, P. A.artículo
closedAccessaccesoRestringido.pdf.jpg26-ago-2016Aggregated compound biological signatures facilitate phenotypic drug discovery and target elucidationCortés Cabrera, Álvaro CSIC ORCID; Lucena-Agell, Daniel CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fasching, Bernhard; Petrone, Paula M.artículo
closedAccess15-jul-2010Cyclosporine A-induced nitration of tyrosine 34 MnSOD in endothelial cells: role of mitochondrial superoxideRedondo-Horcajo, Mariano CSIC ORCID ; Romero, Natalia; Martínez-Acedo, Pablo CSIC; Martínez-Ruiz, Antonio CSIC ORCID; Quijano, Celia; Lourenço, Catia F.; Movilla, Nieves; Enríquez, José Antonio; Rodríguez-Pascual, Fernando CSIC ORCID; Rial, Eduardo CSIC ORCID ; Radi, Rafael; Vázquez, Jesús CSIC ORCID CVN; Lamas Peláez, Santiago CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg26-nov-2014Design and synthesis of pironetin analogue/colchicine hybrids and study of their cytotoxic activity and mechanisms of interaction with tubulinVilanova, Concepción; Díaz-Oltra, Santiago; Murga, Juan; Falomir, Eva; Carda, Miguel; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Marco, J. Albertoartículo
closedAccessrestringido.pdf.jpg25-feb-2011Development of chromanes as novel inhibitors of the uncoupling proteinsRial, Eduardo CSIC ORCID ; Rodríguez-Sánchez, Leonor CSIC ; Aller, Patricio CSIC; Guisado, Arancha CSIC; González-Barroso, M. Mar; Gallardo-Vara, Eunate CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Castellanos Santamaría, Esther CSIC; Fernández de la Pradilla, Roberto CSIC ORCID; Viso, Alma CSIC ORCID artículo
openAccess2023_Bagherpour_Saman_Nanospain.pdf.jpgabr-2023Development of functionalized microchips for intracellular GSH sensing using BODIPY derivatives as fluorescent probesBagherpour, Saman; Duch, M.; Arjona, María Isabel CSIC ORCID ; Plaza, José Antonio CSIC ORCID ; Vázquez, Patricia; Redondo-Horcajo, Mariano CSIC ORCID ; Suárez, Teresa CSIC ORCID ; Pérez-García, Lluïsacomunicación de congreso
closedAccessrestringido.pdf.jpgoct-2012Fatty acids revert the inhibition of respiration caused by the antidiabetic drug metformin to facilitate their mitochondrial β-oxidationGonzález-Barroso, M. Mar; Anedda, Andrea CSIC; Gallardo-Vara, Eunate CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Rodríguez-Sánchez, Leonor CSIC ; Rial, Eduardo CSIC ORCID artículo
openAccessOncology Reports.2018_Sánchez-Carranza.pdf.jpg18-abr-2018Gallic acid sensitizes paclitaxel-resistant human ovarian carcinoma cells through an increase in reactive oxygen species and subsequent downregulation of ERK activationSánchez-Carranza, Jessica Nayelli; Díaz, José Fernando CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Álvarez, Laura CSIC ORCID; Lastres, Pedro ; Romero, Antonio CSIC ORCID ; Aller, Patricio CSIC; González-Maya, Leticiaartículo
closedAccess22-sep-2008Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stabilityRodríguez-Pascual, Fernando CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Magán-Marchal, Noemi CSIC; Lagares, David CSIC; Martínez-Ruiz, Antonio CSIC ORCID; Kleinert, Hartmut; Lamas Peláez, Santiago CSIC ORCID artículo
openAccessscientific reports_arjona_2021.pdf.jpg16-sep-2021Integrating magnetic capabilities to intracellular chips for cell trappingArjona, María Isabel CSIC ORCID ; González-Manchón, Consuelo CSIC ORCID ; Durán, Sara; Duch, M.; del Real, R. P.; Kadambi, Abhinav; Agusil Antonoff, Juan Pablo; Redondo-Horcajo, Mariano CSIC ORCID ; Pérez-García, Lluïsa; Gómez, Elvira; Suárez, Teresa CSIC ORCID ; Plaza, José Antonio CSIC ORCID artículo
openAccessAdvanced Materials2022Arjona.pdf.jpgabr-2022Intracellular Mechanical Drugs Induce Cell-Cycle Altering and Cell DeathArjona, María Isabel CSIC ORCID ; Duch, Marta; Hernández-Pinto, Alberto; Vázquez, Patricia; Agusil, Juan Pablo; Gómez-Martínez, Rodrigo; Redondo-Horcajo, Mariano CSIC ORCID ; Amirthalingam, Ezhil; Pérez-García, Lluïsa; Suárez, Teresa CSIC ORCID ; Plaza, José Antonio CSIC ORCID artículo
openAccessJ. Biol. Chem.-2003-Fernández-Tornero-21774-81.pdf.jpg13-jun-2003Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonateFernández-Tornero, Carlos CSIC ORCID ; Lozano, R.M. CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Gómez, Ana M. CSIC ORCID ; López, José C.; Quesada, Ernesto CSIC ORCID ; Uriel, Clara CSIC ORCID; Valverde, Serafín; Romero, Antonio CSIC ORCID ; Giménez-Gallego, Guillermo CSICartículo
openAccess2017 Tang et al.pdf.jpg3-jun-2017Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.Tang, Yong; Rodríguez-Salarichs, Javier CSIC; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuoartículo
openAccessJ. Biol. Chem.-2001-Lozano.pdf.jpg21-sep-2001Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activityLozano, R.M. CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Jiménez, M. Angeles CSIC ORCID ; Zilberberg, Lior; Cuevas, Pedro; Bikfalvi, Andreas; Rico, Manuel CSIC; Giménez-Gallego, Guillermo CSICartículo
closedAccessaccesoRestringido.pdf.jpg12-ago-2016Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of PodophyllotoxinAntúnez-Mojica, Mayra; Rodríguez-Salarichs, Javier CSIC; Redondo-Horcajo, Mariano CSIC ORCID ; León, Alejandra; Barasoain, Isabel CSIC ; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Jiménez-Barbero, Jesús CSIC ORCID; Álvarez, Laura CSIC ORCID; Díaz, José Fernando CSIC ORCID artículo
openAccesschembiochem_prota_2017.pdf.jpg16-feb-2017Structural basis of microtubule stabilization by discodermolideProta, Andrea E.; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Smith III, Amos B.; Yang, Chia-Ping H.; McDaid, Hayley M.; Paterson, Ian; Horwitz, Susan; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.artículo
openAccessacsomega_trigili_2016.pdf.jpg13-dic-2016Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer CellsTrigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena CSIC ORCID; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpgsep-2016Synthesis and Anti-Proliferative Activity of Sulfanyltriazolylnaphthalenols and Sulfanyltriazolylnaphthalene-1,4-dionesChaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Yli-Kauhaluoma, Jari; Moreira, Vânia M.artículo
closedAccessaccesoRestringido.pdf.jpg28-feb-2013Synthesis and biological evaluation as microtubule-active agents of several tetrahydrofuran and spiroacetal derivativesCarda, Miguel; Murga, Juan; Paños, Julián; Angulo-Pachón, C.A.; García-Pla, Jorge; Díaz-Oltra, Santiago; Marco, J. Alberto; Trigili, Chiara CSIC; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC artículo