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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
openAccesss41467-022-34793-6.pdf.jpg18-nov-2022A glutamine-based single α-helix scaffold to target globular proteinsEscobedo, Albert; Piccirillo, Jonathan; Aranda, Juan; Diercks, Tammo; Mateos, Borja; Garcia-Cabau, Carla; Sánchez-Navarro, Macarena CSIC ORCID; Topal, Busra; Biesaga, Mateusz; Staby, Lasse; Kragelund, Birthe B.; García, Jesús; Millet, Oscar; Orozco, Modesto; Coles, Murray; Crehuet, Ramón CSIC ORCID; Salvatella, Xavierartículo
closedAccessaccesoRestringido.pdf.jpg2013Backbone FC-H⋯O hydrogen bonds in 2′F-substituted nucleic acidsMartín-Pintado, N. CSIC; Deleavey, G.F.; Portella, G.; Campos-Olivas, Ramón CSIC ORCID; Orozco, Modesto; Damha, Masad J.; González, Carlos CSIC artículo
closedAccessaccesoRestringido.pdf.jpg2015Can A Denaturant Stabilize DNA? Pyridine Reverses DNA Denaturation in Acidic pHPortella, G.; Terrazas, M.; Villegas, N.; González, Carlos CSIC ; Orozco, Modestoartículo
openAccessGonzález_et_al_2023.pdf.jpgjun-2023Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathwayGonzález, Lorena; Díaz, Lucía; Pous, Joan CSIC ORCID ; Baginski, Blazej; Durán-Corbera, Anna CSIC; Scarpa, Margherita; Brun-Heath, Isabelle; Igea, Ana; Martin-Malpartida, Pau; Ruiz, Lidia; Pallara, Chiara; Esguerra, Mauricio; Colizzi, Francesco CSIC ORCID; Mayor-Ruiz, Cristina; Biondi, Ricardo M.; Soliva Fortuny, Robert; Macías, María J.; Orozco, Modesto; Nebreda, Ángel R.artículo
closedAccessaccesoRestringido.pdf.jpg2012Characterization of the impact of alternative splicing on protein dynamics: The cases of glutathione S-transferase and ectodysplasin-A isoformsBarbany, Montserrat CSIC; Morata, Jordi CSIC ORCID; Meyer, Tim; Lois, Sergi CSIC; Orozco, Modesto; Cruz, Xavier de la CSIC ORCIDartículo
openAccesssrep2016.pdf.jpg15-feb-2016Conformational plasticity of RepB, the replication initiator protein of promiscuous streptococcal plasmid pMV158Boer, Roeland CSIC ORCID; Ruiz-Masó, José A. CSIC ORCID ; Rueda, Manuel; Petoukhov, Maxim V.; Machón, Cristina CSIC ORCID ; Svergun, Dmitri I.; Orozco, Modesto; Solar, Gloria del CSIC ORCID ; Coll, Miquel CSIC ORCID artículo
openAccessSaneyoshi_Hisao_et_al.pdf.jpg20-jul-2009Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamerSaneyoshi, Hisao; Mazzini, Stefania; Aviñó, Anna CSIC ORCID; Portella, Guillem; González, Carlos CSIC ; Orozco, Modesto; Márquez, Víctor E.; Eritja Casadellà, Ramón CSIC ORCID artículo
openAccessnar_VGenna_et_al_Controled_2023.pdf.jpg9-jun-2023Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotidesGenna, Vito; Iglesias-Fernández, Javier; Reyes-Fraile, Laura; Villegas, Nuria; Guckian, Kevin; Seth, Punit; Wan, Brad; Cabrero Fernández, Cristina CSIC ORCID; Terrazas, Montserrat CSIC ORCID; Brun-Heath, Isabelle; González, Carlos CSIC ; Sciabola, Simone; Villalobos, Anabella; Orozco, Modestoartículo
openAccess; embargoedAccessNature of Thermal Intermediate.pdf.jpg23-ago-2012Defining the Nature of Thermal Intermediate in 3 State Folding Proteins: Apoflavodoxin, a Study CaseGarcía-Fandiño, R.; Bernadó, Pau; Ayuso-Tejedor, Sara; Sancho, Javier CSIC ORCID; Orozco, Modestoartículo
openAccess13-ene-2010Differential stability of 2′F-ANA•RNA and ANA•RNA hybrid duplexes: Roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibilityWatts, Johnathan K.; Martín-Pintado, N. CSIC; Gomez-Pinto, Irene CSIC ORCID; Schwartzentruber, Jeremy; Portella, Guillem; Orozco, Modesto; González, Carlos CSIC ; Damha, Masad J.artículo
openAccessDNA_Cuppari_Art2019.pdf.jpg9-jul-2019DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control regionCuppari, Anna CSIC; Fernández-Millán, Pablo CSIC ORCID; Battistini, Federica; Tarrés-Soler, Aleix CSIC ORCID ; Lyonnais, Sébastien CSIC ORCID; Iruela, Guillermo; Ruiz-López, Elena CSIC; Enciso, Yuliana CSIC; Rubio-Cosials, Anna CSIC; Prohens, Rafel; Pons, Miquel CSIC ORCID; Alfonso, Carlos CSIC ORCID ; Tóth, Katalin; Rivas, Germán CSIC ORCID CVN ; Orozco, Modesto; Solà, Maria CSIC ORCID artículo
openAccessDNA_Chakraborty.pdf.jpg25-ene-2017DNA structure directs positioning of the mitochondrial genome packaging protein Abf2pChakraborty, Arka CSIC; Lyonnais, Sébastien CSIC ORCID; Battistini, Federica; Hospital, Adam; Medici, Giorgio; Prohens, Rafel; Orozco, Modesto; Vilardell, Josep CSIC ORCID ; Solà, Maria CSIC ORCID artículo
openAccessSoliva_Robert_et_al.pdf.jpg15-nov-2000DNA-triplex stabilizing properties of 8-aminoguanineSoliva Fortuny, Robert; Güimil García, Ramón; Blas, J. Ramón; Eritja Casadellà, Ramón CSIC ORCID ; Asensio, Juan Luis CSIC ORCID; González, Carlos CSIC ; Luque, F. Javier; Orozco, Modestoartículo
closedAccessaccesoRestringido.pdf.jpg2013Dramatic effect of furanose C2′ substitution on structure and stability: Directing the folding of the human telomeric quadruplex with a single fluorine atomMartín-Pintado, N. CSIC; Yahyaee-Anzahaee, M.; Deleavey, G.F.; Portella, G.; Orozco, Modesto; Damha, Masad J.; González, Carlos CSIC artículo
openAccessCubero_Elena_et_al.pdf.jpg15-jun-2001The effect of amino groups on the stability of DNA duplexes and triplexes based on purines derived from inosineCubero, Elena; Güimil García, Ramón; Luque, F. Javier; Eritja Casadellà, Ramón CSIC ORCID ; Orozco, Modestoartículo
openAccessepigenprogra.pdf.jpg2019Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational programJanin, Maxime; Ortiz‑Barahona, Vanessa; Castro de Moura, Manuel; Martínez‑Cardús, Anna; Llinàs‑Arias, Pere; Soler, Marta CSIC; Nachmani, Daphna; Pelletier, Joffrey; Schumann, Ulrike; Calleja‑Cervantes, Maria E.; Morán, Sebastián; Guil, Sonia CSIC ORCID; Bueno-Costa, Alberto; Piñeyro, David CSIC ORCID; Perez‑Salvia, Montserrat; Rosselló‑Tortella, Margalida; Piqué, Laia; Bech‑Serra, Joan J.; Torre, Carolina de la; Vidal, August; Martínez‑Iniesta, María; Martín‑Tejera, Juan F.; Villanueva, Alberto; Arias, Alexandra; Cuartas, Isabel; Aransay, Ana M.; Morales La Madrid, Andres; Carcaboso, Ángel M.; Santa‑Maria, Vicente; Mora, Jaume; Fernández, Agustín F. CSIC ORCID; Fraga, Mario F. CSIC ORCID; Aldecoa, Iban; Pedrosa, Leire; Graus, Francesc; Vidal Sarró, Noemí; Martínez‑Soler, Fina; Tortosa, Avelina; Carrato, Cristina; Balañá, Carmen; Boudreau, Matthew W.; Hergenrother, Paul J.; Kötter, Peter; Entian, Karl‑Dieter; Hench, Jürgen; Frank, Stephan; Mansouri, Sheila; Zadeh, Gelareh; Dans, Pablo D.; Orozco, Modesto; Thomas, George; Blanco, Sandra CSIC ORCID CVN; Seoane, Joan; Preiss, Thomas; Pandolfi, Pier Paolo; Esteller, Manelartículo
closedAccessaccesoRestringido.pdf.jpg2015Exploring the complete mutational space of the LDL receptor LA5 domain using molecular dynamics: Linking snps with disease phenotypes in familial hypercholesterolemiaAngarica, V.E.; Orozco, Modesto; Sancho, Javier CSIC ORCIDartículo
openAccessSuriñach_et_al_2023_postprint.pdf.jpgene-2023High-Throughput Prediction of the Impact of Genetic Variability on Drug Sensitivity and Resistance Patterns for Clinically Relevant Epidermal Growth Factor Receptor Mutations from Atomistic SimulationsSuriñach, Aristarc; Hospital, Adam; Westermaier, Yvonne; Jordà, Luis; Orozco-Ruiz, Sergi; Beltrán, Daniel; Colizzi, Francesco CSIC ORCID; Andrio, Pau; Soliva Fortuny, Robert; Municoy, Martí; Gelpí, Josep Lluis; Orozco, Modestoartículo
openAccessgkw1355.pdf.jpg2017How accurate are accurate force-fields for B-DNA?Dans, Pablo D.; Ivani, I.; Hospital, Adam ; Portella, G.; González, Carlos CSIC ; Orozco, Modestoartículo
openAccessCC_REl-Khoury_2023.pdf.jpg16-feb-2023i-Motif folding intermediates with zero-nucleotide loops are trapped by 2'-fluoroarabinocytidine via F···H and O···H hydrogen bondsEl-Khoury, Roberto; Macaluso, Veronica; Hennecker, Christopher; Mittermaier, Anthony K.; Orozco, Modesto; González, Carlos CSIC ; Garavís, Miguel CSIC ORCID; Damha, Masad J.artículo