English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/96601
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Asymmetric formal carbonyl-ene reactions of formaldehyde tert -butyl hydrazone with α-keto esters: Dual activation by bis-urea catalysts

AuthorsCrespo-Peña, Ana; Monge, David; Martín-Zamora, Eloísa; Álvarez, Eleuterio ; Fernández, Rafael ; Lassaletta, José M.
Issue Date2012
PublisherAmerican Chemical Society
CitationJournal of the American Chemical Society 134: 12912- 12915 (2012)
AbstractThe dual activation of α-keto esters and formaldehyde tert-butyl hydrazone by BINAM-derived bis-ureas is the key to achieve high reactivity and excellent enantioselectivities in nucleophilic addition (formal carbonyl-ene reaction) to functionalized tertiary carbinols. Ensuing high-yielding diazene-to-aldehyde tranformations and subsequent derivatizations provides a direct entry to a variety of densely functionalized products. © 2012 American Chemical Society.
Identifiersdoi: 10.1021/ja305209w
issn: 0002-7863
Appears in Collections:(IIQ) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.