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Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/71011
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dc.contributor.authorPichardo, C.-
dc.contributor.authorConejo, María del Carmen-
dc.contributor.authorDocobo-Pérez, Fernando-
dc.contributor.authorVelasco, C.-
dc.contributor.authorLópez-Rojas, Rafael-
dc.contributor.authorGarcía, I.-
dc.contributor.authorPachón-Ibáñez, M. E.-
dc.contributor.authorRodríguez-Martínez, José-Manuel-
dc.contributor.authorPachón, Jerónimo-
dc.contributor.authorPascual, Álvaro-
dc.date.accessioned2013-03-04T11:17:40Z-
dc.date.available2013-03-04T11:17:40Z-
dc.date.issued2011-
dc.identifierdoi: 10.1007/s10096-010-1084-y-
dc.identifierissn: 0934-9723-
dc.identifier.citationEuropean Journal of Clinical Microbiology and Infectious Diseases 30(2): 289-291 (2011)-
dc.identifier.urihttp://hdl.handle.net/10261/71011-
dc.description.abstractZinc eluted from siliconized latex (SL) increases resistance of Pseudomonas aeruginosa to imipenem in vitro. A foreign body peritonitis model was used to evaluate the activity of imipenem using SL or silicone (S) implants. No differences were observed in mortality, positive blood cultures and tissue bacterial counts between SL and S implants. Implant-associated counts, however, were significantly higher in the SL group. It is concluded that SL decreases the activity of imipenem against P. aeruginosa.-
dc.description.sponsorshipThis work was supported by the Dirección General de Investigación del Ministerio de Ciencia y Tecnología, Spain (project SAF2003-01241) and by Ministerio de Ciencia e Innovación, Instituto de Salud Carlos III, co-financed by European Development Regional Fund “A way to achieve Europe” ERDF, Spanish Network for the Research in Infectious Diseases (REIPI RD06/0008). There are no conflicts of interest regarding this work.-
dc.language.isoeng-
dc.publisherSpringer Nature-
dc.rightsclosedAccess-
dc.titleLocal imipenem activity against Pseudomonas aeruginosa decreases in vivo in the presence of siliconized latex-
dc.typeartículo-
dc.identifier.doi10.1007/s10096-010-1084-y-
dc.date.updated2013-03-04T11:17:40Z-
dc.description.versionPeer Reviewed-
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeartículo-
item.fulltextNo Fulltext-
item.languageiso639-1en-
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