Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/66998
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Mas-Barreiro, Antonio | es_ES |
dc.contributor.author | López-Galíndez, Cecilio | es_ES |
dc.contributor.author | Cacho, Isabel | es_ES |
dc.contributor.author | Gómez-Castilla, Jordi | es_ES |
dc.contributor.author | Martínez, M. A. | es_ES |
dc.date.accessioned | 2013-02-20T10:27:49Z | - |
dc.date.available | 2013-02-20T10:27:49Z | - |
dc.date.issued | 2010 | - |
dc.identifier | doi: 10.1016/j.jmb.2010.02.005 | - |
dc.identifier | issn: 0022-2836 | - |
dc.identifier.citation | Journal of Molecular Biology 397: 865- 877 (2010) | es_ES |
dc.identifier.uri | http://hdl.handle.net/10261/66998 | - |
dc.description.abstract | Experimental evidence that RNA virus populations consist of distributions of mutant genomes, termed quasispecies, was first published 31years ago. This work provided the earliest experimental support for a theory to explain a system that replicated with limited fidelity and to understand the self-organization and adaptability of early life forms on Earth. High mutation rates and quasispecies dynamics of RNA viruses are intimately related to both viral disease and antiviral treatment strategies. Moreover, the quasispecies concept is being applied to other biological systems such as cancer research in which cellular mutant spectra can be also detected. This review addresses some of the unanswered questions regarding viral and theoretical quasispecies concepts as well as more practical aspects concerning resistance to antiviral treatments and pathogenesis. © 2010 Elsevier Ltd. | - |
dc.language.iso | eng | es_ES |
dc.publisher | Academic Press | es_ES |
dc.rights | closedAccess | - |
dc.title | Unfinished stories on viral quasispecies and darwinian views of evolution | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1016/j.jmb.2010.02.005 | - |
dc.date.updated | 2013-02-20T10:27:49Z | - |
dc.description.version | Peer Reviewed | - |
dc.relation.csic | Sí | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.openairetype | artículo | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
Aparece en las colecciones: | (IPBLN) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
80
checked on 29-abr-2024
WEB OF SCIENCETM
Citations
71
checked on 22-feb-2024
Page view(s)
299
checked on 02-may-2024
Download(s)
122
checked on 02-may-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.