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| Título: | Edelfosine induces an apoptotic process in Leishmania infantum that is regulated by the ectopic expression of Bcl-XL and Hrk |
Autor: | Alzate, Juan Fernando; Mollinedo, Faustino CSIC ORCID ; Iglesia-Vicente, Janis de la | Fecha de publicación: | 2008 | Editor: | American Society for Microbiology | Citación: | Antimicrobial Agents and Chemotherapy 52(10): 3779-3782 (2008) | Resumen: | The alkyl-lysophospholipids edelfosine and miltefosine induce apoptosis in Leishmania infantum promastigotes. The finding that edelfosine-induced cell death can be regulated by the ectopic expression of the antiapoptotic and proapoptotic members of the Bcl-2 family of proteins Bcl-XL and Hrk suggests that this process is similar to apoptosis in eukaryotic cells. Copyright © 2008, American Society for Microbiology. All Rights Reserved. | URI: | http://hdl.handle.net/10261/60175 | DOI: | 10.1128/AAC.01665-07 | Identificadores: | doi: 10.1128/AAC.01665-07 issn: 0066-4804 e-issn: 1098-6596 |
| Aparece en las colecciones: | (IBMCC) Artículos |
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| Edelfosine Induces.pdf | 706,88 kB | Adobe PDF |  Visualizar/Abrir |
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