Packing of the FMDV 3Dpol-3B1 complex in the P212121 crystals [Dataset]

Ferrer-Orta, Cristina; Ferrero, Diego; Verdaguer, Núria

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Título:	Packing of the FMDV 3Dpol-3B1 complex in the P212121 crystals [Dataset]
Autor:	Ferrer-Orta, Cristina CSIC ORCID ; Ferrero, Diego CSIC ORCID ; Verdaguer, Núria CSIC ORCID
Palabras clave:	Structural biology approaches Mouth disease virus div >< p Different functions within Almost symmetric way Linked immunosorbent assays Play essential roles Concentrate viral rna Two uridine molecules pol Pol Another critical interaction Animal pathogen foot Region ii presenting Higher binding affinity Binding protein responsible 3b1 complex Dependent rna polymerase 3b1 region ii Pprimer protein 3b Elisa assays show Viral rna Protein primer Region ii Assays show Small protein Replication complex Highest affinity Essential component Functional binding Fmdv 3b1 Replication requires Replication occurs Replication machinery Picornavirus replication Membranous compartments Identical copies Host factors Basic residues Based pull Also participate Also catalysed 3b uridylylation
Fecha de publicación:	1-may-2023
Editor:	Figshare
Citación:	Ferrer-Orta, Cristina; Ferrero, Diego; Verdaguer, Núria; 2023; Packing of the FMDV 3Dpol-3B1 complex in the P212121 crystals [Dataset]; Figshare; https://doi.org/10.1371/journal.ppat.1011373.s004
Resumen:	(A) Table showing the different contact surfaces calculated with PISA [41]. (B) Two different of the views of the packing contacts (related by a 90° rotation). The unit cell represented as a reference. The long 3Dpol-3B1 fibers, formed along the ab diagonal, are highlighted in green and yellow as in Fig 2, and the contacting neighbours in grey. (C) Close up views showing the main interacting regions.
Versión del editor:	https://doi.org/10.1371/journal.ppat.1011373.s004
URI:	http://hdl.handle.net/10261/351391
DOI:	10.1371/journal.ppat.1011373.s004
Referencias:	Ferrer-Orta, Cristina; Ferrero, Diego; Verdaguer, Núria. Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranas. https://doi.org/10.1371/journal.ppat.1011373 . http://hdl.handle.net/10261/335548
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