Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/345824
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors |
Autor: | Rosini, Michela; Mancini, Francesca; Tarozzi, Andrea; Colizzi, Francesco CSIC ORCID; Andrisano, Vincenza; Bolognesi, Maria Laura; Hrelia, Patrizia; Melchiorre, Carlo | Palabras clave: | Fructose-1,6-bisphosphatase inhibitors Type 2 diabetes Cyclopenta[b]quinoline derivatives Allosteric inhibitors Anilinoquinazolines |
Fecha de publicación: | dic-2006 | Editor: | Elsevier | Citación: | Bioorganic and Medicinal Chemistry 14(23): 7846-7853 (2006) | Resumen: | In a search for structurally new inhibitors of fructose-1,6-bisphosphatase (F16BPase), substituted 2,3-dihydro-1H-cyclopenta[b]quinoline derivatives were synthesized. It has been shown that the 2,3-dihydro-1H-cyclopenta[b]quinoline moiety may represent a suitable scaffold for the synthesis of potent F16BPase inhibitors endowed with significantly lower EGFR tyrosine kinase inhibitory activity | Descripción: | 8 pages, 4 figures, 1 table | Versión del editor: | https://doi.org/10.1016/j.bmc.2006.07.059 | URI: | http://hdl.handle.net/10261/345824 | DOI: | 10.1016/j.bmc.2006.07.059 | ISSN: | 0968-0896 |
Aparece en las colecciones: | (ICM) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Rosini_et_al_2006_postprint.pdf | 291,61 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
11
checked on 25-abr-2024
WEB OF SCIENCETM
Citations
9
checked on 16-feb-2024
Page view(s)
29
checked on 27-abr-2024
Download(s)
10
checked on 27-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.