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Título: | Possible effects of counterions on biological activities of anionic surfactants |
Autor: | Maugras, Michel; Infante, María Rosa CSIC ; Gerardin-Charbonnier, C.; Selve, Claude; Vinardell, M. Pilar CSIC ORCID | Palabras clave: | Anionic surfactants Apoptosis Cellular membrane Counterions Cytotoxicity Lysine Necrosis Tris U937 cell line |
Fecha de publicación: | abr-2001 | Editor: | Elsevier | Citación: | Comparative Biochemistry and Physiology - C - Toxicology and Pharmacology 128(4): 541-545 (2001) | Resumen: | The aggressiveness in terms of apogenic and necrotic activities of lysine-derived anionic surfactants towards a mammalian cell line (U937) were studied. We used N(alpha)N(epsilon)-dioctanoyl lysine as the model surfactant with lysine, tris, Na(+) or Li(+) as counterions. The aggressiveness of the different surfactants was assessed as the concentrations leading to apoptosis or necrosis after the cells were incubated in the presence of surfactants and then cultivated in their absence. Used in the same conditions, acetates associated with the same cations, had no effects on the cells. Our results show that the aggressiveness of the surfactants depended on the nature of the counterions: it was high when surfactants were associated with small counterions, and low with large counterions. | Versión del editor: | https://doi.org/10.1016/S1532-0456(01)00174-0 | URI: | http://hdl.handle.net/10261/332752 | DOI: | 10.1016/s1532-0456(01)00174-0 | ISSN: | 1532-0456 | E-ISSN: | 1878-1659 |
Aparece en las colecciones: | (CID) Artículos |
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