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Título: | Additional file 5 of Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study |
Autor: | Rodríguez-Fernández, Blanca; Vilor-Tejedor, Natalia; Arenaza-Urquijo, Eider M.; Sánchez-Benavides, Gonzalo; Suárez-Calvet, Marc; Operto, Grégory; Minguillón, Carolina CSIC ORCID; Fauria, Karine; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Castro de Moura, Manuel; Piñeyro, David CSIC ORCID; Esteller, Manel; Blennow, Kaj; Zetterberg, Henrik; De Vivo, Immaculata; Molinuevo, José Luis; Navarro, Arcadi CSIC ORCID ; Gispert, Juan Domingo; Sala-Vila, Aleix; Crous-Bou, Marta | Palabras clave: | Alzheimer’s disease Cerebrospinal fluid biomarkers Mendelian randomization Neuroimaging Polygenic risk score Telomere length |
Fecha de publicación: | 8-nov-2022 | Editor: | Figshare | Citación: | Rodríguez-Fernández, Blanca; Vilor-Tejedor, Natalia; Arenaza-Urquijo, Eider M.; Sánchez-Benavides, Gonzalo; Suárez-Calvet, Marc; Operto, Grégory; Minguillón, Carolina; Fauria, Karine; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Castro de Moura, Manuel; Piñeyro, David; Esteller, Manel; Blennow, Kaj; Zetterberg, Henrik; De Vivo, Immaculata; Molinuevo, José Luis; Navarro, Arcadi; Gispert, Juan Domingo; Sala-Vila, Aleix; Crous-Bou, Marta; 2022; Additional file 5 of Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study [Dataset]; Figshare; https://doi.org/10.6084/m9.figshare.21515115.v1 | Resumen: | Additional file 5: Supplementary Figure 1. Leave-one-out permutation analysis plot for AD signature among individuals at high genetic predisposition to AD obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. Supplementary Figure 2. Leave-one-out permutation analysis plot for Aging signature among individuals at high genetic predisposition to AD, obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. Supplementary Figure 3. Leave-one-out permutation analysis plot for Aβ ratio among APOE-ɛ4 non-carriers obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. Supplementary Figure 4. Leave-one-out permutation analysis plot for NfL among APOE-ɛ4 non-carriers obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. Supplementary Figure 5. Leave-one-out permutation analysis plot for p-tau among individuals at high genetic predisposition to AD, obtained by leaving out the SNP indicated and repeating the Inverse-Variance Weighted method with the rest of the instrumental variables. | Versión del editor: | https://doi.org/10.6084/m9.figshare.21515115.v1 | URI: | http://hdl.handle.net/10261/311633 | DOI: | 10.6084/m9.figshare.21515115.v1 | Referencias: | Rodríguez-Fernández, Blanca; Vilor-Tejedor, Natalia; Arenaza-Urquijo, Eider M.; Sánchez-Benavides, Gonzalo; Suárez-Calvet, Marc; Operto, Grégory; Minguillón, Carolina; Fauria, Karine; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Castro de Moura, Manuel; Piñeyro, David; Esteller, Manel; Blennow, Kaj; Zetterberg, Henrik; De Vivo, Immaculata; Molinuevo, José Luis; Navarro, Arcadi; Gispert, Juan Domingo; Sala-Vila, Aleix; Crous-Bou, Marta; ALFA study. Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study. https://doi.org/10.1186/s13195-022-01101-9 . http://hdl.handle.net/10261/295450udy Rodríguez-Fernández, Blanca; Vilor-Tejedor, Natalia; Arenaza-Urquijo, Eider M.; Sánchez-Benavides, Gonzalo; Suárez-Calvet, Marc; Operto, Grégory; Minguillón, Carolina; Fauria, Karine; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Castro de Moura, Manuel; Piñeyro, David; Esteller, Manel; Blennow, Kaj; Zetterberg, Henrik; De Vivo, Immaculata; Molinuevo, José Luis; Navarro, Arcadi; Gispert, Juan Domingo; Sala-Vila, Aleix; Crous-Bou, Marta; 2022; Additional file 1 of Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study [Dataset]; Figshare; https://doi.org/10.6084/m9.figshare.21515103.v1 Rodríguez-Fernández, Blanca; Vilor-Tejedor, Natalia; Arenaza-Urquijo, Eider M.; Sánchez-Benavides, Gonzalo; Suárez-Calvet, Marc; Operto, Grégory; Minguillón, Carolina; Fauria, Karine; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Castro de Moura, Manuel; Piñeyro, David; Esteller, Manel; Blennow, Kaj; Zetterberg, Henrik; De Vivo, Immaculata; Molinuevo, José Luis; Navarro, Arcadi; Gispert, Juan Domingo; Sala-Vila, Aleix; Crous-Bou, Marta; 2022; Additional file 2 of Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study [Dataset]; Figshare; https://doi.org/10.6084/m9.figshare.21515106.v1 Rodríguez-Fernández, Blanca; Vilor-Tejedor, Natalia; Arenaza-Urquijo, Eider M.; Sánchez-Benavides, Gonzalo; Suárez-Calvet, Marc; Operto, Grégory; Minguillón, Carolina; Fauria, Karine; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Castro de Moura, Manuel; Piñeyro, David; Esteller, Manel; Blennow, Kaj; Zetterberg, Henrik; De Vivo, Immaculata; Molinuevo, José Luis; Navarro, Arcadi; Gispert, Juan Domingo; Sala-Vila, Aleix; Crous-Bou, Marta; 2022; Additional file 3 of Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study [Dataset]; Figshare; https://doi.org/10.6084/m9.figshare.21515109.v1 Rodríguez-Fernández, Blanca; Vilor-Tejedor, Natalia; Arenaza-Urquijo, Eider M.; Sánchez-Benavides, Gonzalo; Suárez-Calvet, Marc; Operto, Grégory; Minguillón, Carolina; Fauria, Karine; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Castro de Moura, Manuel; Piñeyro, David; Esteller, Manel; Blennow, Kaj; Zetterberg, Henrik; De Vivo, Immaculata; Molinuevo, José Luis; Navarro, Arcadi; Gispert, Juan Domingo; Sala-Vila, Aleix; Crous-Bou, Marta; 2022; Additional file 4 of Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study [Dataset]; Figshare; https://doi.org/10.6084/m9.figshare.21515112.v1 |
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