Principal component analysis (PCA) of urine samples (N = 38) on the basis of log2 normalized relative quantities (Rq) of profiled miRNAs using qPCR

Gòdia, Marta; Brogaard, Louise; Mármol-Sánchez, Emilio; Langhorn, Rebecca; Nordang Kieler, Ida; Reezigt, Bert Jan; Nielsen, Lise Nikolic; Jessen, Lisbeth Rem; Cirera, Susanna

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Título:	Principal component analysis (PCA) of urine samples (N = 38) on the basis of log2 normalized relative quantities (Rq) of profiled miRNAs using qPCR
Autor:	Gòdia, Marta CSIC ORCID; Brogaard, Louise; Mármol-Sánchez, Emilio CSIC ORCID; Langhorn, Rebecca; Nordang Kieler, Ida; Reezigt, Bert Jan; Nielsen, Lise Nikolic; Jessen, Lisbeth Rem; Cirera, Susanna
Palabras clave:	Small RNA sequencing Regulate gene expression Nine differentially abundant Likely cellular origin Urinary mirna profiles Six additional mirnas 11 ), cats 10 ), cats Secreted urinary mirnas Feline urinary mirnaome Chronic kidney disease 5 ), cats Invasive urinary biomarkers 102 da mirnas Div><p Identified 212 mirnas Healthy control cats Comparing control cats Shown diagnostic potential Relevant da mirnas Invasive biomarkers Healthy cats Urinary micrornaome ><0 5 ) Seven mirnas Detected mirnas 13 mirnas Eight cats Feline kidney Comparing pn Control study Pn cats Urological conditions Urological condition Ureteral obstruction Transcriptional level Time pcr Susclinical bacteriuria Quantitative real Qpcr alone Qpcr ) Putative novel Prospective case Previously identified P Nearly 71 Including annotated Human nephropathies Five groups First time Coding rnas 05 )
Fecha de publicación:	20-jul-2022
Editor:	Figshare
Citación:	Gòdia, Marta; Brogaard, Louise; Mármol-Sánchez, Emilio; Langhorn Rebecca; Nordang Kieler, Ida; Reezigt, Bert Jan; Nielsen, Lise Nikolic; Jessen, Lisbeth Rem; Cirera, Susanna; 2022; Principal component analysis (PCA) of urine samples (N = 38) on the basis of log2 normalized relative quantities (Rq) of profiled miRNAs using qPCR [Dataset]; Figshare; https://doi.org/10.1371/journal.pone.0270067.s005
Resumen:	All samples together (all groups), as well as each one of the contrasts considered (Controls vs. PN; Control vs. SB/C; Control vs. UO; Control vs. CKD; PN vs. SB/C; PN vs. UO; PN vs. CKD and PN vs. other Pathologies) are shown. CKD: Chronic kidney disease; PN: Pyelonephritis; SB/C: Subclinical bacteriuria/Cystitis; UO: Ureteral obstruction.
Descripción:	1 figure.
Versión del editor:	https://doi.org/10.1371/journal.pone.0270067.s005
URI:	http://hdl.handle.net/10261/310610
DOI:	10.1371/journal.pone.0270067.s005
Referencias:	Gòdia, Marta; Brogaard, Louise; Mármol-Sánchez, Emilio; Langhorn, Rebecca; Nordang Kieler, Ida; Reezigt, Bert Jan; Nielsen, Lise Nikolic; Jessen, Lisbeth Rem; Cirera, Susanna. Urinary microRNAome in healthy cats and cats with pyelonephritis or other urological conditions. PLoS ONE 17(7): e0270067 (2022). https://doi.org/10.1371/journal.pone.0270067. http://hdl.handle.net/10261/287004
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