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Título: | Ontogeny of IgM and IgM-bearing cells in rainbow trout |
Autor: | Castillo, Araceli G.; Sánchez, Carmen; Domínguez, Javier; Kaattari, S. L.; Villena, A. | Palabras clave: | Immunoglobulin M (IgM) B-cells Immunocompetence Ontogeny Trout Teleost |
Fecha de publicación: | 1993 | Editor: | Elsevier | Citación: | Developmental and Comparative Immunology 17(5): 419-424 (1993) | Resumen: | We have studied the ontogenic development of immunoglobulin M (IgM) and of IgM-bearing cells in the rainbow trout, Oncorhynchus mykiss. Lymphocytes showing cytoplasmic IgM were first observed in embryos at 12 days before hatch (14°C). At this stage, no cells positive for surface IgM were present. Lymphocytes bearing surface IgM were observed at 8 days before hatch (14°C). Unfertilized trout eggs contained detectable amounts of IgM (11.2 ± 2.6 μg/g of egg weight), indicating that transfer of IgM from mother to embryo can occur in salmonids. The levels of IgM from whole fish increase slowly after the appearance of intraembryonic cells that express surface IgM. The amount of IgM/g of tissue peaks around hatch, but this parameter shows lower values up to 2 months after hatch. © 1993. | URI: | http://hdl.handle.net/10261/295152 | DOI: | 10.1016/0145-305X(93)90033-M | ISSN: | 0145-305X |
Aparece en las colecciones: | (INIA) Artículos |
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