Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/289355
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Occupational IgE-mediated allergy after exposure to lupine seed flour |
Autor: | Fernández Crespo, Jesús; Rodríguez, Julia; Vives, R.; James, Jeremy J.; Reaño, M.; Daroca, P.; Burbano, C.; Muzquiz, M. | Palabras clave: | Lupine Hypersensitivity Legum Occupational Asthma Bronchial provocation test |
Fecha de publicación: | 2001 | Editor: | Elsevier | Citación: | Journal of Allergy and Clinical Immunology 108(2): 295-297 (2001) | Resumen: | The ingestion of lupine seed flour (LSF) has been reported as a cause of allergic reactions, particularly in patients sensitized to peanut, but there is little evidence of its allergenic potential after inhalation. We sought to evaluate the clinical and immunologic reactivity to lupine in employees working with this seed flour. An occupational history was obtained in 7 subjects (median age, 35 years) working with LSF at an agricultural research center. Three subjects (1, 6, and 7) reported work-related allergy symptoms immediately after being exposed to lupine. Skin prick test results with LSF extract were positive in these 3 patients with work-related symptoms. Moreover, lupine-specific IgE antibodies were detected in subjects 6 and 7. In subject 6, the controlled exposure to LSF elicited immediate naso-ocular symptoms without changes in FEV1. In subject 7, a bronchial provocation with LSF extract elicited an immediate fall (25%) in FEV1. Double-blinded, placebo-controlled LSF oral challenge results were positive in subjects 6 and 7. Immunologic reactivity to other legumes was detected in subjects 6 and 7, but specific inhalation testing and oral challenge results were negative. Thus, the inhalation of lupine flour could be an important cause of allergic sensitization in exposed workers and might give rise to occupational asthma and food allergy. | URI: | http://hdl.handle.net/10261/289355 | DOI: | 10.1067/mai.2001.116860 | ISSN: | 0091-6749 |
Aparece en las colecciones: | (INIA) Artículos |
Mostrar el registro completo
CORE Recommender
SCOPUSTM
Citations
66
checked on 11-may-2024
WEB OF SCIENCETM
Citations
51
checked on 27-feb-2024
Page view(s)
22
checked on 15-may-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.