Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/264867
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Oller, Jorge | - |
dc.contributor.author | Gabandé-Roldríguez, Enrique | - |
dc.contributor.author | Ruíz-Rodríguez, María J. | - |
dc.contributor.author | Desdín-Mico, Gabriela | - |
dc.contributor.author | Aranda, Juan Francisco | - |
dc.contributor.author | Rodriguez-Díez, Raquel | - |
dc.contributor.author | Ballesteros-Martínez, Constanza | - |
dc.contributor.author | Blanco, Eva M. | - |
dc.contributor.author | Roldan-Montero, Raquel | - |
dc.contributor.author | Acuña, Pedro | - |
dc.contributor.author | Forteza Gil, Alberto | - |
dc.contributor.author | Martín-López, Carlos E. | - |
dc.contributor.author | Nistal, J. Francisco | - |
dc.contributor.author | Lino Cardenas, Christian L | - |
dc.contributor.author | Lindsay, Mark Evan | - |
dc.contributor.author | Martín-Ventura, Jose Luis | - |
dc.contributor.author | Briones, Ana M. | - |
dc.contributor.author | Miguel Redondo, Juan | - |
dc.contributor.author | Mittelbrunn, María | - |
dc.date.accessioned | 2022-03-22T12:30:03Z | - |
dc.date.available | 2022-03-22T12:30:03Z | - |
dc.date.issued | 2021-05-21 | - |
dc.identifier | doi: 10.1161/CIRCULATIONAHA.120.051171 | - |
dc.identifier | issn: 1524-4539 | - |
dc.identifier.citation | Circulation 143: 2091- 2109 (2021) | - |
dc.identifier.uri | http://hdl.handle.net/10261/264867 | - |
dc.description.abstract | Marfan syndrome (MFS) is an autosomal dominant disorder of the connective tissue caused by mutations in the FBN1 (fibrillin-1) gene encoding a large glycoprotein in the extracellular matrix called fibrillin-1. The major complication of this connective disorder is the risk to develop thoracic aortic aneurysm. To date, no effective pharmacologic therapies have been identified for the management of thoracic aortic disease and the only options capable of preventing aneurysm rupture are endovascular repair or open surgery. Here, we have studied the role of mitochondrial dysfunction in the progression of thoracic aortic aneurysm and mitochondrial boosting strategies as a potential treatment to managing aortic aneurysms. | - |
dc.description.sponsorship | Fondo de Investigacion Sanitaria del Instituto de Salud Carlos III (PI16/188, PI19/855), the European Regional D evelopment Fund, and the European Commission through H2020-EU.1.1, European Research Council grant ERC-2016-StG 715322-EndoMitTalk, and Gobierno de Espana SAF2016-80305P. This work was partially supported by Comunidad de Madrid (S2017/BMD 3867 RENIM-CM) and cofinanced by the European Structural and Investment Fund. M.M. is supported by the Miguel Servet Program (CP 19/014, Fundacion de Investigacion del Hospital 12 de Octubre | - |
dc.language | eng | - |
dc.publisher | American Heart Association | - |
dc.relation.isversionof | Publisher's version | - |
dc.rights | openAccess | - |
dc.title | Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1161/CIRCULATIONAHA.120.051171 | - |
dc.relation.publisherversion | http://dx.doi.org/10.1161/CIRCULATIONAHA.120.051171 | - |
dc.date.updated | 2022-03-22T12:30:03Z | - |
dc.rights.license | https://creativecommons.org/licenses/by/4.0/ | - |
dc.contributor.funder | Instituto de Salud Carlos III | - |
dc.contributor.funder | European Commission | - |
dc.contributor.funder | Comunidad de Madrid | - |
dc.contributor.funder | Instituto de Investigación Hospital 12 de Octubre | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100004587 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/100012818 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.identifier.pmid | 33709773 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairetype | artículo | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Aparece en las colecciones: | (CBM) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
MittelbrunnMExtracellularTuning.pdf | 4,21 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
30
checked on 28-abr-2024
SCOPUSTM
Citations
50
checked on 06-may-2024
WEB OF SCIENCETM
Citations
45
checked on 27-feb-2024
Page view(s)
50
checked on 07-may-2024
Download(s)
109
checked on 07-may-2024