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http://hdl.handle.net/10261/224841
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Bautista, Leonelo Enrique | es_ES |
dc.contributor.author | Bajwa, P. K. | es_ES |
dc.contributor.author | Shafer, Martin Merrill | es_ES |
dc.contributor.author | Malecki, Kristen M.C. | es_ES |
dc.contributor.author | McWilliams, Christine A. | es_ES |
dc.contributor.author | Palloni, Alberto | es_ES |
dc.date.accessioned | 2020-12-14T16:39:52Z | - |
dc.date.available | 2020-12-14T16:39:52Z | - |
dc.date.issued | 2019-08 | - |
dc.identifier.citation | International Journal of Cardiology Hypertension, vol. 2: 100012 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10261/224841 | - |
dc.description.abstract | Inconsistencies in studies of chronic psychosocial stress and hypertension may be explained by the use of stress markers greatly influenced by circadian rhythm and transient stressors. We assessed whether hair cortisol, a marker that captures systemic cortisol over months, was independently associated with hypertension. We measured hair cortisol and blood pressure in 75 consecutive participants in the Survey of the Health of Wisconsin, using an ELISA test. Individuals with values ≥ median (78.1 pg/mg) were considered exposed. We used approximate Bayesian logistic regression, with a prior odds ratio of 1.0–4.0, to quantify the multivariate-adjusted hair cortisol-hypertension association. Participants' average age was 46.9 years; 37.3% were male; and 25.3% were hypertensive. Hypertension prevalence was 2.23 times higher in exposed (95% CI: 1.69–3.03). This finding was unlikely explained by differential measurement errors, since we conducted blinded measurements of exposure and outcome. Sensitivity analyses showed the association was unlikely explained by an unmeasured confounder, survival bias, or reverse causality bias. Findings suggest elevated hair cortisol is a risk factor for hypertension. Although feasible, the clinical value of hair cortisol as a tool for hypertension risk stratification or for monitoring the effect of chronic psychosocial stress management interventions is still uncertain. | es_ES |
dc.description.sponsorship | Research reported in this publication was supported by the National Institute on Aging of the National Institutes of Health under Award Number P30AG017266. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.isversionof | Publisher's version | es_ES |
dc.rights | openAccess | es_ES |
dc.subject | Blood pressure | es_ES |
dc.subject | Chronic psychosocial stress | es_ES |
dc.subject | Cortisol | es_ES |
dc.subject | Hair cortisol | es_ES |
dc.subject | Hypertension | es_ES |
dc.title | The relationship between chronic stress, hair cortisol and hypertension | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1016/j.ijchy.2019.100012 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.1016/j.ijchy.2019.100012 | es_ES |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S2590086219300126 | es_ES |
dc.identifier.e-issn | 2590-0862 | - |
dc.rights.license | http://creativecommons.org/licenses/by-nc-nd/4.0/ | es_ES |
dc.contributor.funder | National Institute on Aging (US) | es_ES |
dc.relation.csic | No | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.contributor.orcid | Palloni, Alberto [0000-0002-2263-2207] | es_ES |
dc.identifier.pmid | 33447745 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.openairetype | artículo | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
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Chronic_stress_hair_cortisol_hypertension.pdf | 560,58 kB | Adobe PDF | Visualizar/Abrir |
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