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Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways

AuthorsKlein, Hannah L.; Gómez-González, Belén ; Aguilera, Andrés ; Kim, Nayun; Lisby, Michael; Malkova, Anna
Issue Date2019
PublisherShared Science Publishers OG
CitationMicrobial Cell 6(1): 1-64 (2019)
AbstractUnderstanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily be manipulated. Cellular assays comprise genetic, molecular, and cytological reporters. The assays are powerful tools but each comes with its particular advantages and limitations. Here the most commonly used assays are reviewed, discussed, and presented as the guidelines for future studies.
Description2019 Klein et al.
Publisher version (URL)https://doi.org/10.15698/mic2019.01.664
Appears in Collections:(CABIMER) Artículos
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