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http://hdl.handle.net/10261/192812
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Abou Assi, H. | - |
dc.contributor.author | Garavís, Miguel | - |
dc.contributor.author | González, Carlos | - |
dc.contributor.author | Damha, Masad J. | - |
dc.date.accessioned | 2019-10-17T10:27:44Z | - |
dc.date.available | 2019-10-17T10:27:44Z | - |
dc.date.issued | 2018-08-16 | - |
dc.identifier | doi: 10.1093/nar/gky735 | - |
dc.identifier | issn: 1362-4962 | - |
dc.identifier.citation | Nucleic Acids Research 46: 8038-8056 (2018) | - |
dc.identifier.uri | http://hdl.handle.net/10261/192812 | - |
dc.description | 19 pags., 7 figs. | - |
dc.description.abstract | The i-motif represents a paradigmatic example of the wide structural versatility of nucleic acids. In remarkable contrast to duplex DNA, i-motifs are four-stranded DNA structures held together by hemi- protonated and intercalated cytosine base pairs (C:C+). First observed 25 years ago, and considered by many as a mere structural oddity, interest in and discussion on the biological role of i-motifs have grown dramatically in recent years. In this review we focus on structural aspects of i-motif formation, the factors leading to its stabilization and recent studies describing the possible role of i-motifs in fundamental biological processes. | - |
dc.description.sponsorship | Natural Sciences and Engineering Research Council of Canada (NSERCC); MINECO grant [BFU2017-89707-P]; Juan de la Cierva postdoctoral Fellowship [FJCI-2016-28474 to M.G.]. Funding for open access charge: NSERCC Discovery grant ( to M.J.D.); MINECO grant [BFU2017-89707-P to C.G.]. | - |
dc.publisher | Oxford University Press | - |
dc.relation | info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2017-89707-P | - |
dc.relation.isversionof | Publisher's version | - |
dc.rights | openAccess | - |
dc.title | i-Motif DNA: Structural Features and Significance to Cell Biology | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1093/nar/gky735 | - |
dc.relation.publisherversion | https://doi.org/10.1093/nar/gky735 | - |
dc.date.updated | 2019-10-17T10:27:45Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | eng | - |
dc.rights.license | http://creativecommons.org/licenses/by/4.0 | - |
dc.contributor.funder | SCOAP | - |
dc.contributor.funder | Natural Sciences and Engineering Research Council of Canada | - |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000038 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.identifier.pmid | 30124962 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.openairetype | artículo | - |
item.fulltext | With Fulltext | - |
Aparece en las colecciones: | (IQF) Artículos |
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Fichero | Descripción | Tamaño | Formato | |
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gky735.pdf | 5,54 MB | Adobe PDF | Visualizar/Abrir |
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