Bioactive compounds isolated from Senecio kingii, S. magellanicus and S. candidans from the Magallanic Región of Chile

Abstract

The genus Senecio (Asteraceae), is distributed worldwide and consists around of 3.000 species. These species are mainly characterized by the presence of pyrrolizidine alkaloids, furanoeremophilanes and flavonoids which have several biological activities (biopesticide, cytotoxic, anti-inflammatory, anti-microbial and anti-oxidant). In the present work we report on the isolation and structural elucidation of bioctive metabolites from S. kingii, an endemic plant species from the Magellan region (Chile). The structures of the compounds were established by mono-bidimensional NMR spectroscopic techniques, chemical correlation and comparison of bibliographic data. The insecticidal and fungicidal activities of fractions were assayed according to previously described methodology, showing significant activity.