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Microfluidic pneumatic cages: A novel approach for in-chip crystal trapping, manipulation and controlled chemical treatment

AuthorsAbrishamkar, Afshin; Paradinas, Markos; Bailo, Elena; Rodríguez-Trujillo, Romen; Pfattner, Raphael ; Rossi, René; Ocal, Carmen ; deMello, Andrew J.; Amabilino, David B. ; Puigmartí Luis, Josep
Double-layer chips
Pneumatic cages
Chemical engineering
Controlled chemical treatment
Issue 113
Issue Date2016
PublisherJournal of Visualized Experiments
CitationJournal of Visualized Experiments 113: e54193 (2016)
AbstractThe precise localization and controlled chemical treatment of structures on a surface are significant challenges for common laboratory technologies. Herein, we introduce a microfluidic-based technology, employing a double-layer microfluidic device, which can trap and localize in situ and ex situ synthesized structures on microfluidic channel surfaces. Crucially, we show how such a device can be used to conduct controlled chemical reactions onto on-chip trapped structures and we demonstrate how the synthetic pathway of a crystalline molecular material and its positioning inside a microfluidic channel can be precisely modified with this technology. This approach provides new opportunities for the controlled assembly of structures on surface and for their subsequent treatment.
Publisher version (URL)http://dx.doi.org/10.3791/54193
Identifiersdoi: 10.3791/54193
e-issn: 1940-087X
Appears in Collections:(ICMAB) Artículos
(CIN2) Artículos
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