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Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/112737
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dc.contributor.authorOlalde, Iñigo-
dc.contributor.authorSánchez-Quinto, Federico-
dc.contributor.authorMarigorta, Urko M.-
dc.contributor.authorRodríguez-Pérez, Juan Antonio-
dc.contributor.authorFernández-Callejo, Marcos-
dc.contributor.authorMatas-Lalueza, Marta-
dc.contributor.authorRamírez, Óscar-
dc.contributor.authorNavarro, Arcadi-
dc.contributor.authorMarqués-Bonet, Tomàs-
dc.contributor.authorLalueza-Fox, Carles-
dc.date.accessioned2015-03-20T11:05:26Z-
dc.date.available2015-03-20T11:05:26Z-
dc.date.issued2014-04-24-
dc.identifierdoi: 10.1038/srep04666-
dc.identifierissn: 2045-2322-
dc.identifier.citationScientific Reports 4: 4666 (2014)-
dc.identifier.urihttp://hdl.handle.net/10261/112737-
dc.descriptionOlalde, Iñigo et al.-- This work is licensed under a Creative Commons Attribution 3.0 Unported License.-
dc.description.abstractA pyrographically decorated gourd, dated to the French Revolution period, has been alleged to contain a handkerchief dipped into the blood of the French king Louis XVI (1754-1793) after his beheading but recent analyses of living males from two Bourbon branches cast doubts on its authenticity. We sequenced the complete genome of the DNA contained in the gourd at low coverage (∼2.5×) with coding sequences enriched at a higher ∼7.3× coverage. We found that the ancestry of the gourd's genome does not seem compatible with Louis XVI's known ancestry. From a functional perspective, we did not find an excess of alleles contributing to height despite being described as the tallest person in Court. In addition, the eye colour prediction supported brown eyes, while Louis XVI had blue eyes. This is the first draft genome generated from a person who lived in a recent historical period; however, our results suggest that this sample may not correspond to the alleged king.-
dc.description.sponsorshipThis work is supported by FEDER and Spanish Government grants BFU2012-38236 and the Spanish Multiple Sclerosis Netowrk (REEM) of the Instituto de Salud Carlos III (RD12/0032/0011) to A.N., BFU2011-28549 and ERC Starting Grant (260372) to T.M.-B. and BFU2012-34157 to C.L.-F. and S.C., and a predoctoral fellowship from the Basque Government (DEUI) to I.O.-
dc.publisherNature Publishing Group-
dc.relation.isversionofPublisher's version-
dc.rightsopenAccess-
dc.titleGenomic analysis of the blood attributed to Louis XVI (1754-1793), king of France-
dc.typeartículo-
dc.identifier.doi10.1038/srep04666-
dc.relation.publisherversionhttp://dx.doi.org/10.1038/srep04666-
dc.date.updated2015-03-20T11:05:26Z-
dc.description.versionPeer Reviewed-
dc.language.rfc3066eng-
dc.rights.licensehttp://creativecommons.org/licenses/by/3.0-
dc.contributor.funderEuropean Commission-
dc.contributor.funderRed Española de Esclerosis Múltiple-
dc.contributor.funderEuropean Research Council-
dc.contributor.funderEusko Jaurlaritza-
dc.contributor.funderMinisterio de Ciencia e Innovación (España)-
dc.relation.csicSí-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000780es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100007747es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000781es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100004837es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003086es_ES
dc.identifier.pmid24763138-
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextopen-
item.openairetypeartículo-
item.fulltextWith Fulltext-
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