Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/112583
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | A study on the induction of stereoselectivity in the Strecker synthesis of basic amino acid-derived α-amino nitriles |
Autor: | Ventosa-Andrés, Pilar CSIC; García-López, M. Teresa CSIC ; Herranz, Rosario CSIC ORCID | Fecha de publicación: | 2012 | Editor: | Elsevier | Citación: | Tetrahedron Asymmetry 23: 1198-1205 (2012) | Resumen: | Diverse basic amino acid-derived α-amino nitriles have been synthesized via a modified Strecker reaction, using TMSCN as the cyanide source. It has been found that this synthesis is a slow thermodynamically controlled reaction, where it was difficult to induce stereocontrol. Moderate selectivity was induced by thermodynamic control of the reaction in MeOH. The absolute configuration at the stereogenic center generated was assigned by chemical correlation with 2-oxopiperazine derivatives. | URI: | http://hdl.handle.net/10261/112583 | DOI: | 10.1016/j.tetasy.2012.07.009 | Identificadores: | doi: 10.1016/j.tetasy.2012.07.009 issn: 0957-4166 e-issn: 1362-511X |
Aparece en las colecciones: | (IQM) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Tetra Asymmetry-2012.pdf | 511,79 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
4
checked on 24-abr-2024
WEB OF SCIENCETM
Citations
4
checked on 21-feb-2024
Page view(s)
291
checked on 26-abr-2024
Download(s)
285
checked on 26-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.