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Browsing by Author Unzeta, Mercedes

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Showing results 1 to 14 of 14
RightsPreviewIssue DateTitleAuthor(s)Type
closedAccessaccesoRestringido.pdf.jpg2013A therapeutic approach to cerebrovascular diseases based on indole substituted hydrazides and hydrazines able to interact with human vascular adhesion protein-1, monoamine oxidases (A and B), AChE and BuChEEsteban, Gerard; Bolea, Irene; Sun, Ping; Solé, Montserrat  ; Samadi, Abdelouahid ; Marco-Contelles, José ; Unzeta, Mercedesartículo
closedAccessaccesoRestringido.pdf.jpg2013Analysis of the antioxidant properties of differently substituted 2- and 3-indolyl carbohydrazides and related derivativesHadjipavlou-Litina, Dimitra; Samadi, Abdelouahid ; Unzeta, Mercedes; Marco-Contelles, José artículo
openAccessASS234 As a New Multi-Target Directed.pdf.jpg28-Jun-2016ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease TherapyMarco-Contelles, José ; Unzeta, Mercedes; Bolea, Irene; Esteban, Gerard; Ramsay, Rona R.; Romero, Alejandro ; Martínez-Murillo, Ricardo ; Carreiras, M. Carmo; Ismaili, L.artículo
closedAccessaccesoRestringido.pdf.jpg26-Feb-2015Catecholaminergic and cholinergic systems of mouse brain are modulated by LMN diet, rich in theobromine, polyphenols and polyunsaturated fatty acidsFernández-Fernández, Laura; Valente, Tony ; Unzeta, Mercedesartículo
closedAccessaccesoRestringido.pdf.jpg2014Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's diseaseBautista-Aguilera, Óscar M.; Esteban, Gerard; Bolea, Irene; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid ; Soriano, Elena ; Unzeta, Mercedes; Marco-Contelles, José artículo
closedAccessaccesoRestringido.pdf.jpg2014Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's diseaseWang, L.; Esteban, Gerard; Ojima, Masaki; Bautista-Aguilera, Óscar M.; Inokuchi, Tsutomu; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid ; Youdim, Moussa B. H.; Romero, Alejandro ; Soriano, Elena ; Herrero, Raquel; Fernández Fernández, Ana Patricia ; Martínez-Murillo, Ricardo ; Marco-Contelles, José ; Unzeta, Mercedesartículo
closedAccessaccesoRestringido.pdf.jpg2014Effects of novel monoamine oxidases and cholinesterases targeting compounds on brain neurotransmitters and behavior in rat model of vascular dementiaStasiak, Anna; Mussur, Miroslaw; Unzeta, Mercedes; Samadi, Abdelouahid ; Marco-Contelles, José ; Fogel, W. Agnieszkaartículo
closedAccessaccesoRestringido.pdf.jpg2014Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's diseaseEsteban, Gerard; Allan, Jennifer; Samadi, Abdelouahid ; Mattevi, Andrea; Unzeta, Mercedes; Marco-Contelles, José ; Binda, Claudia; Ramsay, Rona R.artículo
openAccessMulti-Target Directed Donepezil-Like.pdf.jpg25-May-2016Multi-Target Directed Donepezil-Like Ligands for Alzheimer's DiseaseUnzeta, Mercedes; Esteban, Gerard; Bolea, Irene; Fogel, W. Agnieszka; Ramsay, Rona R.; Youdim, Moussa B. H.; Tipton, Keith Francis; Marco-Contelles, José artículo
openAccessDrug Design, Development and Therapy.pdf.jpg2014Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: Design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybridsBautista-Aguilera, Oscar M.; Esteban, Gerard; Chioua, Mourad  ; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Soriano, Elena ; Samadi, Abdelouahid ; Unzeta, Mercedes; Marco-Contelles, José artículo
closedAccessaccesoRestringido.pdf.jpg2013Multipotent, permeable drug ASS234 inhibits Aβ aggregation, possesses antioxidant properties and protects from Aβ-induced apoptosis in vitroBolea, Irene; Gella, Alejandro; Monjas, Leticia ; Pérez, Concepción; Rodríguez-Franco, María Isabel ; Marco-Contelles, José ; Samadi, Abdelouahid ; Unzeta, Mercedesartículo
closedAccessaccesoRestringido.pdf.jpg2014Neuroprotective effects of the MAO-B inhibitor, PF9601N, in an in vivo model of excitotoxicityBolea, Irene; Colivicchi, María Alessandra; Ballini, Chiara; Marco-Contelles, José ; Tipton, Keith Francis; Unzeta, Mercedes; Della Corte, Lauraartículo
openAccessES2365316A1.pdf.jpg29-Sep-2011Nuevos derivados de propargilamina con capacidad neuroprotectora para el tratamiento de las enfermedades de Alzheimer y ParkinsonSamadi, Abdelouahid ; Marco-Contelles, José ; Bolea Tomás, Irene; Luque, Francisco J.; Unzeta, Mercedessolicitud de patente
openAccessVila et al-Biochem Pharmacol 2019-POSTPRINT.pdf.jpgJun-2019Uric acid treatment after stroke modulates the Krüppel-like factor 2-VEGF-A axis to protect brain endothelial cell functions: Impact of hypertensionVila, Elisabet; Solé, Montserrat  ; Masip, Núria; Puertas-Umbert, Lídia; Amaro, Sergio; Dantas, Ana Paula; Unzeta, Mercedes; D'Ocón, Pilar; Planas, Anna M. ; Chamorro, Ángel; Jiménez-Altayó, Francescartículo