Mostrando resultados 13 a 31 de 31
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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| openAccess |  | 15-jun-2022 | Discovering potential interactions between rare diseases and COVID-19 by combining mechanistic models of viral infection with statistical modeling | López-Sánchez, Macarena; Loucera, Carlos CSIC ORCID; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID | artículo |
| openAccess |  | 11-dic-2020 | Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection | Loucera, Carlos CSIC ORCID; Esteban-Medina, Marina CSIC ORCID; Rian, Kinza; Falco, Matias M.; Dopazo, Joaquín CSIC ORCID; Peña-Chilet, María CSIC ORCID | carta al director |
| openAccess | | 2023 | Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches | Niarakis, Anna; Ostaszewski, Marek; Mazein, Alexander; Kuperstein, Inna; Kutmon, Martina; Gillespie, Marc E.; Funahashi, Akira; Acencio, Marcio Luis; Hemedan, Ahmed; Aichem, Michael; Klein, Karsten; Czauderna, Tobias; Burtscher, Felicia; Yamada, Takahiro G.; Hiki, Yusuke; Hiroi, Noriko F.; Hu, Finterly; Pham, Nhung; Ehrhart, Friederike; Willighagen, Egon L.; Valdeolivas, Alberto; Dugourd, Aurelien; Messina, Francesco; Esteban-Medina, Marina CSIC ORCID; Peña-Chilet, María CSIC ORCID; Rian, Kinza; Soliman, Sylvain; Aghamiri, Sara Sadat; Lal Puniya, Bhanwar; Naldi, Aurelien; Helikar, Tomas; Singh, Vidisha; Fariñas Fernández, Marco; Bermudez, Viviam; Tsirvouli, Eirini; Montagud, Arnau; Noël, Vincent; Ponce de León, Miguel; Maier, Dieter; Bauch, Angela; Gyori, Benjamin M.; Bachman, John A.; Luna, Augustin; Piñero, Janet; Furlong, Laura I.; Balaur, Irina BalaurIrina; Rougny, Adrien; Jarosz, Yohan; Overall, Rupert W.; Phair, Robert; Perfetto, Livia; Matthews, Lisa; Balaya Rex, Devasahayam Arokia; Orlic-Milacic, Marija; Monraz Gómez, Luis Cristóbal; De Meulder, Bertrand; Ravel, Jean Marie; Jassal, Bijay; Satagopam, Venkata; Wu, Guanming; Golebiewski, Martin; Gawron, Piotr; Calzone, Laurence; Beckmann, Jacques S.; Evelo, Chris T.; D’Eustachio, Peter; Schreiber, Falk; Sáez-Rodríguez, Julio; Dopazo, Joaquín CSIC ORCID; Kuiper, Martin; Valencia, Alfonso; Wolkenhauer, Olaf; Kitano, Hiroaki; Barillot, Emmanuel; Auffray, Charles; Balling, Rudi; Schneider, Reinhard; COVID- Disease Map Community the COVID-19 Disease Map Community | artículo |
| openAccess |  | 1-oct-2023 | Functional Profiling of Soft Tissue Sarcoma Using Mechanistic Models | Payá-Milans, Miriam CSIC ORCID; Peña-Chilet, María CSIC ORCID; Loucera, Carlos CSIC ORCID; Esteban-Medina, Marina CSIC ORCID; Dopazo, Joaquín CSIC ORCID | artículo |
| openAccess |  | 2021 | Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data | Rian, Kinza; Hidalgo, Marta R.; Çubuk, Cankut; Falco, Matias M.; Loucera, Carlos CSIC ORCID; Esteban-Medina, Marina CSIC ORCID; Alamo-Alvarez, Inmaculada CSIC ORCID; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID | artículo |
| openAccess |  | 21-ene-2021 | Mechanistic modeling of the SARS-CoV-2 disease map | Rian, Kinza; Esteban-Medina, Marina CSIC ORCID; Hidalgo, Marta R.; Çubuk, Cankut; Falco, Matias M.; Loucera, Carlos CSIC ORCID; Gunyel, Devrim; Ostaszewski, Marek; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID | artículo |
| openAccess |  | 29-jun-2020 | Mechanistic Models of Signaling Pathways Reveal the Drug Action Mechanisms behind Gender-Specific Gene Expression for Cancer Treatments | Çubuk, Cankut; Can, Fatma E.; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID | artículo |
| openAccess | | nov-2023 | microRNAs-mediated regulation of insulin signaling in white adipose tissue during aging: Role of caloric restriction | Corrales, Patricia; Martin-Taboada, Marina; Vivas-García, Yurena; Torres, Lucia; Ramírez-Jiménez, Laura; López, Yamila; Horrillo, Daniel; Vila-Bedmar, Rocío CSIC; Barber-Cano, Eloisa; Izquierdo-Lahuerta, Adriana; Peña-Chilet, María CSIC ORCID; Martínez, Carmen; Dopazo, Joaquín CSIC ORCID; Ros, Manuel; Medina-Gómez, Gema | artículo |
| openAccess | | nov-2023 | microRNAs-mediated regulation of insulin signaling in white adipose tissue during aging: Role of caloric restriction [Dataset] | Corrales, Patricia; Martin-Taboada, Marina; Vivas-García, Yurena; Torres, Lucia; Ramírez-Jiménez, Laura; López, Yamila; Horrillo, Daniel; Vila-Bedmar, Rocío CSIC; Barber-Cano, Eloisa; Izquierdo-Lahuerta, Adriana; Peña-Chilet, María CSIC ORCID; Martínez, Carmen; Dopazo, Joaquín CSIC ORCID; Ros, Manuel; Medina-Gómez, Gema | dataset |
| openAccess |  | 11-nov-2013 | Modelling MC1R rare variants: A structural evaluation of variants detected in a Mediterranean case-control study | Ibarrola-Villava, Maider; Peña-Chilet, María CSIC ORCID; Llorca-Cardeñosa, Marta J.; Oltra, Sara; Martinez-Cadenas, Conrado; Bravo, Jerónimo CSIC ORCID ; Ribas, Gloria | artículo |
| openAccess |  | 14-oct-2021 | Mutational Characterization of Cutaneous Melanoma Supports Divergent Pathways Model for Melanoma Development | Millán-Esteban, David; Peña-Chilet, María CSIC ORCID; García-Casado, Zaida; Manrique-Silva, Esperanza; Requena, Celia; Bañuls, José; López-Guerrero, José Antonio CSIC ORCID; Rodríguez-Hernández, Aranzazu; Traves, Víctor; Dopazo, Joaquín CSIC ORCID; Virós, Amaya; Kumar, Rajiv; Nagore, Eduardo | artículo |
| openAccess |  | 2020 | Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial | Martín-Broto, Javier CSIC ORCID; Hindi, Nadia CSIC ORCID; Grignani, Giovanni; Martínez-Trufero, Javier; Redondo, Andrés; Valverde, Claudia M.; Stacchiotti, Silvia; López-Pousa, Antonio; D'Ambrosio, Lorenzo; Gutiérrez, Antonio; Pérez-Vega, Herminia; Encinas-Tobajas, Víctor; Álava, Enrique de CSIC ORCID; Collini, Paola; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID; Carrasco-García, Irene; López-Álvarez, María; Moura, David S. CSIC ORCID; López-Martín, José A. | artículo |
| closedAccess |  | ene-2019 | Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial | Martín-Broto, Javier CSIC ORCID; Stacchiotti, Silvia; López-Pousa, Antonio; Redondo, Andrés; Bernabeu, Daniel; Álava, Enrique de CSIC ORCID; Casali, Paolo G.; Italiano, Antoine; Gutiérrez, Antonio; Moura, David S. CSIC ORCID; Peña-Chilet, María CSIC ORCID; Díaz-Martín, J. CSIC ORCID; Biscuola, Michele CSIC ORCID; Taron Roca, Miguel CSIC; Collini, Paola; Ranchere-Vince, Dominique; García del Muro, Xavier; Grignani, Giovanni; Dumont, Sarah; Martínez-Trufero, Javier; Palmerini, Emanuela; Hindi, Nadia CSIC ORCID; Sebio, Ana; Dopazo, Joaquín CSIC ORCID; Dei Tos, Angelo Paolo; LeCesne, Axel; Blay, Jean-Yves; Cruz Jurado, Josefina | artículo |
| closedAccess |  | mar-2020 | Pazopanib for treatment of typical solitary fibrous tumours: a multicentre, single-arm, phase 2 trial | Martín-Broto, Javier CSIC ORCID; Cruz Jurado, Josefina; Penel, Nicolas; Le Cesne, Axel; Hindi, Nadia CSIC ORCID; Luna, Pablo; Moura, David S. CSIC ORCID; Bernabeu, Daniel; Álava, Enrique de CSIC ORCID; López-Guerrero, José Antonio CSIC ORCID; Dopazo, Joaquín CSIC ORCID; Peña-Chilet, María CSIC ORCID; Gutiérrez, Antonio; Collini, Paola; Karanian, Marie; Redondo, Andrés; López-Pousa, Antonio; Grignani, Giovanni; Díaz-Martín, J. CSIC ORCID; Marcilla-Plaza, David; Fernández-Serra, Antonio; González-Aguilera, Cristina CSIC; Casali, Paolo G.; Blay, Jean-Yves; Stacchiotti, Silvia | artículo |
| openAccess |  | 3-dic-2021 | Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients | Loucera, Carlos CSIC ORCID; Peña-Chilet, María CSIC ORCID; Esteban-Medina, Marina CSIC ORCID; Muñoyerro-Muñiz, Dolores; Villegas-Portero, Román; López-Miranda, José; Rodríguez-Baño, Jesús CSIC ORCID; Túnez, Isaac; Bouillon, Roger; Dopazo, Joaquín CSIC ORCID; Quesada-Gómez, José Manuel | artículo |
| openAccess |  | 16-ago-2022 | Real-world evidence with a retrospective cohort of 15,968 Andalusian COVID-19 hospitalized patients suggests 21 new effective treatments and one drug that increases death risk | Loucera, Carlos CSIC ORCID; Carmona, Rosario CSIC ORCID; Esteban-Medina, Marina CSIC ORCID; Bostelmann, Gerrit; Muñoyerro-Muñiz, Dolores; Villegas-Portero, Román; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID | preprint |
| openAccess | | 6-oct-2023 | Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments | Loucera, Carlos CSIC ORCID; Carmona, Rosario CSIC ORCID; Esteban-Medina, Marina CSIC ORCID; Bostelmann, Gerrit; Muñoyerro-Muñiz, Dolores; Villegas, Román; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID | artículo |
| openAccess | | 6-oct-2023 | Supplementary Material: Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments | Loucera, Carlos CSIC ORCID; Carmona, Rosario CSIC ORCID; Esteban-Medina, Marina CSIC ORCID; Bostelmann, Gerrit; Muñoyerro-Muñiz, Dolores; Villegas, Román; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID | dataset |
| openAccess |  | 2022 | Towards a metagenomics machine learning interpretable model for understanding the transition from adenoma to colorectal cancer | Casimiro-Soriguer, Carlos S. CSIC ORCID CVN; Loucera, Carlos CSIC ORCID; Peña-Chilet, María CSIC ORCID; Dopazo, Joaquín CSIC ORCID | artículo |
