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Título: | Apoptosis in the trabecular meshwork of glaucomatous patients |
Autor: | Baleriola, Jimena CSIC ORCID; García-Feijóo, Julián; Martínez de la Casa, José M.; Fernández-Cruz, Arturo; De la Rosa, Enrique J. CSIC ORCID ; Fernández-Durango, Raquel | Fecha de publicación: | 2008 | Editor: | Molecular Vision | Citación: | Molecular Vision 14:1513-1516(2008) | Resumen: | We established and validated an in toto method to perform TdT-mediated dUTP nick end labeling to study apoptosis in human trabecular meshwork tissue obtained during trabeculectomy in glaucoma patients. In specimens from patients with primary open-angle glaucoma and primary angle-closure glaucoma, we detected a tendency for more apoptotic cells to accumulate in patients with primary open-angle glaucoma. The utility of this method to study apoptosis in the trabecular meshwork is discussed, as well as its application as a tool in biologic samples | Descripción: | 4 p.-2 fig.-1 tab. | URI: | http://hdl.handle.net/10261/59062 | ISSN: | 1090-0535 | E-ISSN: | 1090-0535 |
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