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| Título: | TSAO Derivatives: Highly Specific Inhibitors of Human Immunodeficiency Virus Type-1 (HIV-1) Replication |
Autor: | Camarasa Rius, María José CSIC ORCID; Peréz-Pérez, María-Jesús CSIC ORCID ; Velázquez, Sonsoles CSIC ORCID CVN; San-Félix, Ana CSIC ORCID ; Álvarez, Rosa; Jimeno, M. Luisa CSIC ORCID | Fecha de publicación: | 1995 | Editor: | Taylor & Francis | Citación: | Nucleosides, Nucleotides and Nucleic Acids 14 (3 & 5) : 585 - 594 (1995) | Resumen: | TSAO derivatives represent a unique class of nucleosides that are specifically targeted at HIV-1 RT. This overview is focussed on the chemical synthesis, the conformational studies, the antiviral and metabolic properties of TSAO derivatives, as well as their mechanism of antiviral action and the molecular basis of the rapid selection of resistant HIV-1 strains that emerge in cell culture in the presence of TSAO derivatives. | Versión del editor: | http://dx.doi.org/10.1080/15257779508012432 | URI: | http://hdl.handle.net/10261/36426 | DOI: | 10.1080/15257779508012432 |
| Aparece en las colecciones: | (CENQUIOR) Artículos (IQM) Artículos |
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