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Título: | Plain Language Summary of the iNNOVATE study: ibrutinib plus rituximab is well-tolerated and effective in people with Waldenström's macroglobulinemia |
Autor: | Buske, Christian; Tedeschi, Alessandra; Trotman, Judith; García-Sanz, Ramón; MacDonald, David; Leblond, Véronique; Mahe, Beatrice; Herbaux, Charles; Matous, Jeffrey V.; Heffner, Leonard T.; Varettoni, Marzia; Palomba, M. Lia; Shustik, Chaim; Kastritis, Efstathios; Treon, Steven P.; Ping, Jerry; Hauns, Bernhard; Arango-Hisijara, Israel | Palabras clave: | B-cell lymphoma Ibrutinib Rituximab Waldenström's macroglobulinemia |
Fecha de publicación: | 23-feb-2023 | Editor: | Future Science | Citación: | Future Oncology 19(5): 345-353 (2023) | Resumen: | This article provides a short summary of 5-year results from the iNNOVATE trial. The original paper was published in the Journal of Clinical Oncology in October 2021. People with Waldenström's macroglobulinemia (WM) were randomly divided into two groups of 75 people each. One group received a combination treatment composed of two drugs, ibrutinib plus rituximab, and the other group took placebo (“sugar pill”) plus rituximab. Ibrutinib (also known by the brand name Imbruvica®) is a drug that reduces cancer cells' ability to multiply and survive. Ibrutinib is an FDA-approved drug for the treatment of WM. Rituximab is a drug that helps the immune system find and kill cancer cells. Participants in the trial were treated and their health monitored for up to 5 years (63 months). | Versión del editor: | https://doi.org/10.2217/fon-2022-1015 | URI: | http://hdl.handle.net/10261/352499 | DOI: | 10.2217/fon-2022-1015 | ISSN: | 1479-6694 | E-ISSN: | 1744-8301 |
Aparece en las colecciones: | (IBMCC) Artículos |
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iNNOVATE study_Busque_Art_2023.pdf | 1,68 MB | Adobe PDF | Visualizar/Abrir |
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