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Título: | Transcriptional dissection of pancreatic tumors engrafted in mice |
Autor: | Martinez-Garcia, Raquel; Juan, David CSIC ORCID ; Rausell, Antonio; Muñoz, Manuel; Baños, Natalia; Menéndez, Camino CSIC; Lopez-Casas, Pedro P; Rico, Daniel CSIC ORCID; Valencia, Alfonso; Hidalgo, Manuel CSIC ORCID | Palabras clave: | cancer|xenografts | Fecha de publicación: | 2014 | Editor: | Springer Nature | Citación: | Martinez-Garcia, R., Juan, D., Rausell, A. et al. Transcriptional dissection of pancreatic tumors engrafted in mice. 6, 27 (2014). https://doi.org/10.1186/gm544Genome Medicine | Resumen: | Engraftment of primary pancreas ductal adenocarcinomas (PDAC) in mice to generate patient-derived xenograft (PDX) models is a promising platform for biological and therapeutic studies in this disease. However, these models are still incompletely characterized. Here, we measured the impact of the murine tumor environment on the gene expression of the engrafted human tumoral cells. | Versión del editor: | https://genomemedicine.biomedcentral.com/articles/10.1186/gm544 | URI: | http://hdl.handle.net/10261/346768 | DOI: | 10.1186/gm544 | ISSN: | 1756-994X |
Aparece en las colecciones: | (CNB) Artículos |
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